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Confounding variables are a well known source of nuisance in biomedical studies. They present an even greater challenge when we combine them with black-box machine learning techniques that operate on raw data. This work presents two case…

We develop a systematic, omnibus approach to goodness-of-fit testing for parametric distributional models when the variable of interest is only partially observed due to censoring and/or truncation. In many such designs, tests based on the…

统计方法学 · 统计学 2026-02-10 Juan Carlos Escanciano , Jacobo de Uña-Álvarez

Recently, Saeb et al (2017) showed that, in diagnostic machine learning applications, having data of each subject randomly assigned to both training and test sets (record-wise data split) can lead to massive underestimation of the…

To unbiasedly estimate a causal effect on an outcome unconfoundedness is often assumed. If there is sufficient knowledge on the underlying causal structure then existing confounder selection criteria can be used to select subsets of the…

统计方法学 · 统计学 2017-03-20 Jenny Häggström

The desire to train complex machine learning algorithms and to increase the statistical power in association studies drives neuroimaging research to use ever-larger datasets. The most obvious way to increase sample size is by pooling scans…

计算机视觉与模式识别 · 计算机科学 2020-10-29 Christian Wachinger , Anna Rieckmann , Sebastian Pölsterl

Confirmation bias, the tendency to interpret information in a way that aligns with one's preconceptions, can profoundly impact scientific research, leading to conclusions that reflect the researcher's hypotheses even when the observational…

机器学习 · 统计学 2025-09-09 Amnon Balanov , Tamir Bendory , Wasim Huleihel

Machine learning models are central to people's lives and impact society in ways as fundamental as determining how people access information. The gravity of these models imparts a responsibility to model developers to ensure that they are…

应用统计 · 统计学 2020-07-13 Cyrus DiCiccio , Sriram Vasudevan , Kinjal Basu , Krishnaram Kenthapadi , Deepak Agarwal

Observational data is increasingly used as a means for making individual-level causal predictions and intervention recommendations. The foremost challenge of causal inference from observational data is hidden confounding, whose presence…

机器学习 · 统计学 2018-10-30 Nathan Kallus , Aahlad Manas Puli , Uri Shalit

Statistical modeling plays a fundamental role in understanding the underlying mechanism of massive data (statistical inference) and predicting the future (statistical prediction). Although all models are wrong, researchers try their best to…

统计方法学 · 统计学 2020-06-17 Hangjin Jiang

Causal inference necessarily relies upon untestable assumptions; hence, it is crucial to assess the robustness of obtained results to violations of identification assumptions. However, such sensitivity analysis is only occasionally…

统计方法学 · 统计学 2025-05-19 Tobias Freidling , Qingyuan Zhao

Statistical methods are based on model assumptions, and it is statistical folklore that a method's model assumptions should be checked before applying it. This can be formally done by running one or more misspecification tests of model…

统计方法学 · 统计学 2023-04-18 M. Iqbal Shamsudheen , Christian Hennig

Marginal structural models are a popular tool for investigating the effects of time-varying treatments, but they require an assumption of no unobserved confounders between the treatment and outcome. With observational data, this assumption…

统计方法学 · 统计学 2021-06-10 Matthew Blackwell , Soichiro Yamauchi

Statistics is sometimes described as the science of reasoning under uncertainty. Statistical models provide one view of this uncertainty, but what is frequently neglected is the 'invisible' portion of uncertainty: that assumed not to exist…

统计方法学 · 统计学 2026-03-18 Oliver L. Pescott , Robin J. Boyd , Gary D. Powney , Gavin B. Stewart

Commonsense reasoning is intuitive for humans but has been a long-term challenge for artificial intelligence (AI). Recent advancements in pretrained language models have shown promising results on several commonsense benchmark datasets.…

计算与语言 · 计算机科学 2021-06-03 Shikhar Singh , Nuan Wen , Yu Hou , Pegah Alipoormolabashi , Te-Lin Wu , Xuezhe Ma , Nanyun Peng

Most supervised machine learning tasks are subject to irreducible prediction errors. Probabilistic predictive models address this limitation by providing probability distributions that represent a belief over plausible targets, rather than…

机器学习 · 统计学 2022-10-25 David Widmann , Fredrik Lindsten , Dave Zachariah

In this paper, we investigate the hypothesis testing problem that checks whether part of covariates / confounders significantly affect the heterogeneous treatment effect given all covariates. This model checking is particularly useful in…

统计理论 · 数学 2020-09-24 Niwen Zhou , Xu Guo , Lixing Zhu

Parametric Bayesian modeling offers a powerful and flexible toolbox for machine learning. Yet the model, however detailed, may still be wrong, and this can make inferences untrustworthy. In this paper we introduce a new class of…

统计方法学 · 统计学 2026-04-03 Bohan Wu , Eli N. Weinstein , Sohrab Salehi , Yixin Wang , David M. Blei

Several problems in statistics involve the combination of high-variance unbiased estimators with low-variance estimators that are only unbiased under strong assumptions. A notable example is the estimation of causal effects while combining…

统计方法学 · 统计学 2023-05-25 Michael Oberst , Alexander D'Amour , Minmin Chen , Yuyan Wang , David Sontag , Steve Yadlowsky

Many applications of computational social science aim to infer causal conclusions from non-experimental data. Such observational data often contains confounders, variables that influence both potential causes and potential effects.…

计算与语言 · 计算机科学 2020-05-05 Katherine A. Keith , David Jensen , Brendan O'Connor

One central goal of design of observational studies is to embed non-experimental data into an approximate randomized controlled trial using statistical matching. Despite empirical researchers' best intention and effort to create…

统计方法学 · 统计学 2022-06-22 Kan Chen , Siyu Heng , Qi Long , Bo Zhang