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Confounding seriously impairs our ability to learn about causal relations from observational data. Confounding can be defined as a statistical association between two variables due to inputs from a common source (the confounder). For…

统计方法学 · 统计学 2018-05-17 Anders Ledberg

Causal inference from observational data often assumes "ignorability," that all confounders are observed. This assumption is standard yet untestable. However, many scientific studies involve multiple causes, different variables whose…

机器学习 · 统计学 2019-04-16 Yixin Wang , David M. Blei

Recent work has focused on the potential and pitfalls of causal identification in observational studies with multiple simultaneous treatments. Building on previous work, we show that even if the conditional distribution of unmeasured…

统计方法学 · 统计学 2025-03-28 Jiajing Zheng , Alexander D'Amour , Alexander Franks

Propensity score matching has been a long-standing tradition for handling confounding in causal inference, however requiring stringent model assumptions. In this article, we propose double score matching(DSM) for general causal estimands…

统计方法学 · 统计学 2020-07-07 Shu Yang , Yunshu Zhang

Sensitivity analysis for the unconfoundedness assumption is crucial in observational studies. For this purpose, the marginal sensitivity model (MSM) gained popularity recently due to its good interpretability and mathematical properties.…

统计方法学 · 统计学 2024-02-27 Yao Zhang , Qingyuan Zhao

Conditioning on some set of confounders that causally affect both treatment and outcome variables can be sufficient for eliminating bias introduced by all such confounders when estimating causal effect of the treatment on the outcome from…

统计方法学 · 统计学 2018-04-24 Priyantha Wijayatunga

Estimating causal effects from observational data is challenging due to selection bias, which leads to imbalanced covariate distributions across treatment groups. Propensity score-based weighting methods are widely used to address this…

机器学习 · 计算机科学 2025-08-08 Ahmad Saeed Khan , Erik Schaffernicht , Johannes Andreas Stork

Estimating the causal effects of an intervention in the presence of confounding is a frequently occurring problem in applications such as medicine. The task is challenging since there may be multiple confounding factors, some of which may…

统计方法学 · 统计学 2018-11-28 Sonali Parbhoo , Mario Wieser , Volker Roth

Propensity score methods are increasingly being used to reduce estimation bias of treatment effects for observational studies. Previous research has shown that propensity score methods consistently estimate the marginal hazard ratio for…

统计方法学 · 统计学 2019-11-19 Haodi Liang , Cecilia Cotton

No unmeasured confounding is often assumed in estimating treatment effects in observational data when using approaches such as propensity scores and inverse probability weighting. However, in many such studies due to the limitation of the…

应用统计 · 统计学 2019-08-06 Rong Huang , Ronghui Xu , Parambir S. Dulai

Inference for high-dimensional logistic regression models using penalized methods has been a challenging research problem. As an illustration, a major difficulty is the significant bias of the Lasso estimator, which limits its direct…

统计方法学 · 统计学 2024-10-29 Yuming Zhang , Stéphane Guerrier , Runze Li

Measurement error arises through a variety of mechanisms. A rich literature exists on the bias introduced by covariate measurement error and on methods of analysis to address this bias. By comparison, less attention has been given to errors…

统计方法学 · 统计学 2018-11-27 Pamela Shaw , Jiwei He , Bryan Shepherd

Compositional data arise in many areas of research in the natural and biomedical sciences. One prominent example is in the study of the human gut microbiome, where one can measure the relative abundance of many distinct microorganisms in a…

统计方法学 · 统计学 2024-04-26 Aaron J. Molstad , Karl Oskar Ekvall , Piotr M. Suder

In biomedical research, repeated measurements within each subject are often processed to remove artifacts and unwanted sources of variation. The resulting data are used to construct derived outcomes that act as proxies for scientific…

统计方法学 · 统计学 2026-02-03 Zihang Wang , Razieh Nabi , Benjamin B. Risk

Estimating average causal effect (ACE) is useful whenever we want to know the effect of an intervention on a given outcome. In the absence of a randomized experiment, many methods such as stratification and inverse propensity weighting have…

机器学习 · 计算机科学 2019-07-11 Rathin Desai , Amit Sharma

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

统计方法学 · 统计学 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

The purpose of many health studies is to estimate the effect of an exposure on an outcome. It is not always ethical to assign an exposure to individuals in randomised controlled trials, instead observational data and appropriate study…

In many contexts it is extremely costly to perform enough high quality experimental measurements to accurately parameterize a predictive quantitative model. However, it is often much easier to carry out large numbers of experiments that…

数据分析、统计与概率 · 物理学 2017-11-22 Alpha A. Lee , Michael P. Brenner , Lucy J. Colwell

Functional data analysis, which handles data arising from curves, surfaces, volumes, manifolds and beyond in a variety of scientific fields, is a rapidly developing area in modern statistics and data science in the recent decades. The…

统计方法学 · 统计学 2020-08-21 Xiaoke Zhang , Wu Xue , Qiyue Wang

Studies in environmental and epidemiological sciences are often spatially varying and observational in nature with the aim of establishing cause and effect relationships. One of the major challenges with such studies is the presence of…

统计方法学 · 统计学 2023-05-16 Sayli Pokal , Yawen Guan , Honglang Wang , Yuzhen Zhou