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Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…

图像与视频处理 · 电气工程与系统科学 2025-06-11 Charles Bricout , Samira Ebrahimi Kahou , Sylvain Bouix

The population is aging, and becoming more tech-savvy. The United Nations predicts that by 2050, one in six people in the world will be over age 65 (up from one in 11 in 2019), and this increases to one in four in Europe and Northern…

计算与语言 · 计算机科学 2021-10-19 Kathleen C. Fraser , Majid Komeili

INTRODUCTION: Mild cognitive impairment (MCI) is characterized by a decline in cognitive functions beyond typical age and education-related expectations. Since, MCI has been linked to reduced social interactions and increased aimless…

人工智能 · 计算机科学 2024-08-21 Chaitra Hegde , Yashar Kiarashi , Allan I Levey , Amy D Rodriguez , Hyeokhyen Kwon , Gari D Clifford

The human brain provides a range of functions such as expressing emotions, controlling the rate of breathing, etc., and its study has attracted the interest of scientists for many years. As machine learning models become more sophisticated,…

人机交互 · 计算机科学 2020-05-25 Felix G. Hamza-Lup , Adytia Suri , Ionut E. Iacob , Ioana R. Goldbach , Lateef Rasheed , Paul N. Borza

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

机器学习 · 计算机科学 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

Motor skill acquisition in fields like surgery, robotics, and sports involves learning complex task sequences through extensive training. Traditional performance metrics, like execution time and error rates, offer limited insight as they…

神经元与认知 · 定量生物学 2025-02-21 Anil Kamat , Rahul Rahul , Lora Cavuoto , Harry Burke , Matthew Hackett , Jack Norfleet , Steven Schwaitzberg , Suvranu De

Detection of subtle deficits in everyday functioning due to cognitive impairment is important for early detection of neurodegenerative diseases, particularly Alzheimer's disease. However, current standards for assessment of everyday…

音频与语音处理 · 电气工程与系统科学 2023-09-13 Yasunori Yamada , Kaoru Shinkawa , Masatomo Kobayashi , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Automated online and App-based cognitive assessment tasks are becoming increasingly popular in large-scale cohorts and biobanks due to advantages in affordability, scalability and repeatability. However, the summary scores that such tasks…

神经元与认知 · 定量生物学 2023-05-31 Valentina Giunchiglia , Sharon Curtis , Stephen Smith , Naomi Allen , Adam Hampshire

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

信号处理 · 电气工程与系统科学 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

As shown in computer vision, the power of deep learning lies in automatically learning relevant and powerful features for any perdition task, which is made possible through end-to-end architectures. However, deep learning approaches applied…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Soheil Esmaeilzadeh , Dimitrios Ioannis Belivanis , Kilian M. Pohl , Ehsan Adeli

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Agitation is one of the most common responsive behaviors in people living with dementia, particularly among those residing in community settings without continuous clinical supervision. Timely prediction of agitation can enable early…

信号处理 · 电气工程与系统科学 2025-06-10 Ali Abedi , Charlene H. Chu , Shehroz S. Khan

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

机器学习 · 计算机科学 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

计算机视觉与模式识别 · 计算机科学 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

Background: Impairment of visual spatial cognitive function is the most common early clinical manifestation of Alzheimer's Disease (AD). When the Montreal Cognitive Assessment (MoCA) uses the "0/1" binary method ("pass/fail") to evaluate…

Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in this early phase of disease are challenging due to the slow…

应用统计 · 统计学 2020-03-10 Dan Li , Samuel Iddi , Paul S. Aisen , Wesley K. Thompson , Michael C. Donohue

Human activity recognition using smart home sensors is one of the bases of ubiquitous computing in smart environments and a topic undergoing intense research in the field of ambient assisted living. The increasingly large amount of data…

神经与进化计算 · 计算机科学 2018-04-20 Deepika Singh , Erinc Merdivan , Ismini Psychoula , Johannes Kropf , Sten Hanke , Matthieu Geist , Andreas Holzinger

Accurate diagnosis of Alzheimer's Disease (AD) entails clinical evaluation of multiple cognition metrics and biomarkers. Metrics such as the Alzheimer's Disease Assessment Scale - Cognitive test (ADAS-cog) comprise multiple subscores that…

机器学习 · 统计学 2017-08-16 Lev E. Givon , Laura J. Mariano , David O'Dowd , John M. Irvine , Abraham R. Schneider

Background: Loneliness among students is increasing across the world, with potential consequences for mental health and academic success. To address this growing problem, accurate methods of detection are needed to identify loneliness and…

人机交互 · 计算机科学 2024-04-03 Malik Muhammad Qirtas , Evi Zafeirid , Dirk Pesch , Eleanor Bantry White

Traditional approaches to measurement in upper-limb therapy have gaps that electronic sensing and recording can help fill. We highlight shortcomings in current kinematic recording devices, and we introduce a wrist sensing device that…

机器人学 · 计算机科学 2024-11-20 Jacob Carducci , Jeremy D. Brown