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Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to…

医学物理 · 物理学 2016-02-18 Huajie Han , Shenghao Wang , Kun Gao , Zhili Wang , Can Zhang , Meng Yang , Kai Zhang , Peiping Zhu

We present a multi-aperture analyser set-up for performing X-ray phase contrast imaging in planar and three-dimensional modalities. A multi-slice representation of the sample is used to establish a quantitative relation between projection…

仪器与探测器 · 物理学 2017-06-21 M. Endrizzi , F. A. Vittoria , L. Rigon , D. Dreossi , A. Olivo

One of the most powerful approaches to imaging at the nanometer or subnanometer length scale is coherent diffraction imaging using X-ray sources. For amorphous (non-crystalline) samples, the raw data can be interpreted as the modulus of the…

数值分析 · 数学 2020-04-02 Alexander Barnett , Charles L. Epstein , Leslie Greengard , Jeremy Magland

Differential phase contrast interior tomography allows for reconstruction of a refractive index distribution over a region of interest (ROI) for visualization and analysis of internal structures inside a large biological specimen. In this…

医学物理 · 物理学 2015-05-30 Wenxiang Cong , Ge Wang

X-ray ptychography is a cutting edge imaging technique providing ultra-high spatial resolutions. In ptychography, phase retrieval, i.e., the recovery of a complex valued signal from intensity-only measurements, is enabled by exploiting a…

图像与视频处理 · 电气工程与系统科学 2022-09-14 Felix Wittwer , Peter Modregger

Tilting planar samples for multi-zone-axes observation is a routine procedure in electron microscopy. However, this process invariably introduces optical path differences in the electron beam across different sample positions, significantly…

材料科学 · 物理学 2024-08-22 Jizhe Cui , Yi Zheng , Kang Sun , Wenfeng Yang , Haozhi Sha , Rong Yu

X-ray microtomography is a powerful non-destructive technique allowing 3D virtual histology of resected human tissue. The achievable imaging field-of-view, is however limited by the fixed number of detector elements, enforcing the…

Propagation-based X-ray phase contrast enables nanoscale imaging of biological tissue by probing not only the attenuation, but also the real part of the refractive index of the sample. Since only intensities of diffracted waves can be…

数值分析 · 数学 2017-09-11 Simon Maretzke , Thorsten Hohage

In the hard X rays domain, the phase shift of the wave passing through the soft materials like tissues is typically three orders of magnitude larger than the absorption. Therefore the phase-sensitive X-ray imaging methods can obtain…

仪器与探测器 · 物理学 2018-06-12 Lian Chen , Rongqi Sun , Ge Jin

X-ray phase-contrast imaging can provide greatly improved contrast over conventional absorption-based imaging for weakly absorbing samples, such as biological soft tissues and fibre composites. In this manuscript, we introduce an easy and…

软件工程 · 计算机科学 2015-04-21 Shenghao Wang , Huajie Han , Kun Gao , Zhili Wang , Can Zhang , Meng Yang , Zhao Wu , Augusto Marcelli , Ziyu Wu

Phase Contrast Imaging (PCI), Dark-Field (DF) and Directional Dark-Field (DDF) imaging are recent X-ray imaging modalities that have demonstrated their interest by providing access to information and contrasts different from those provided…

图像与视频处理 · 电气工程与系统科学 2023-04-25 Clara Magnin , Laurene Quenot , Sylvain Bohic , Dan Mihai Cenda , Manuel Fernández Martínez , Blandine Lantz , Bertrand Faure , Emmanuel Brun

We study an approach to solving the phase retrieval problem as it arises in a phase-less imaging modality known as ptychography. In ptychography, small overlapping sections of an unknown sample (or signal, say $x_0\in \mathbb{C}^d$) are…

数值分析 · 数学 2019-10-09 Brian Preskitt , Rayan Saab

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

图像与视频处理 · 电气工程与系统科学 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

Phase reconstruction is important in transmission electron microscopy for structural studies. We describe electron Fourier ptychography and its application to phase reconstruction of both radiation-resistant and beam-sensitive materials. We…

X-ray phase-contrast tomography (XPCT) is widely used for high contrast 3D imaging using either synchrotron or laboratory microfocus X-ray sources. XPCT enables an order of magnitude improvement in image contrast of the reconstructed…

图像与视频处理 · 电气工程与系统科学 2024-10-28 K. Aditya Mohan , Jean-Baptiste Forien , Venkatesh Sridhar , Jefferson A. Cuadra , Dilworth Parkinson

We present an alternative numerical reconstruction algorithm for direct tomographic reconstruction of a sample refractive indices from the measured intensities of its far-field coherent diffraction patterns. We formulate the well-known…

计算物理 · 物理学 2019-02-06 T. Ramos , Bastian E. Grønager , Martin Skovgaard Andersen , J. W. Andreasen

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

计算机视觉与模式识别 · 计算机科学 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

In Bragg Coherent Diffraction Imaging (BCDI), Phase Retrieval of highly strained crystals is often challenging with standard iterative algorithms. This computational obstacle limits the potential of the technique as it precludes the…

X-ray imaging has conventionally relied upon attenuation to provide contrast. In recent years, two complementary modalities have been added; phase contrast and dark-field x-ray imaging, capturing weakly attenuating and sub-pixel sample…

光学 · 物理学 2021-11-16 Kaye S. Morgan , David M. Paganin

Magnetic Resonance Imaging (MRI) is a powerful, non-invasive diagnostic tool; however, its clinical applicability is constrained by prolonged acquisition times. Whilst present deep learning-based approaches have demonstrated potential in…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Anurag Malyala , Zhenlin Zhang , Chengyan Wang , Chen Qin