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Multiple hypothesis testing, a situation when we wish to consider many hypotheses, is a core problem in statistical inference that arises in almost every scientific field. In this setting, controlling the false discovery rate (FDR), which…

统计理论 · 数学 2019-03-19 Shiyun Chen , Shiva Kasiviswanathan

In the context of high-dimensional Gaussian linear regression for ordered variables, we study the variable selection procedure via the minimization of the penalized least-squares criterion. We focus on model selection where the penalty…

统计理论 · 数学 2024-07-01 Perrine Lacroix , Marie-Laure Martin

The False Discovery Rate (FDR) is a new statistical procedure to control the number of mistakes made when performing multiple hypothesis tests, i.e. when comparing many data against a given model hypothesis. The key advantage of FDR is that…

In large-scale multiple hypothesis testing problems, the false discovery exceedance (FDX) provides a desirable alternative to the widely used false discovery rate (FDR) when the false discovery proportion (FDP) is highly variable. We…

统计方法学 · 统计学 2023-04-21 Pallavi Basu , Luella Fu , Alessio Saretto , Wenguang Sun

As the volume and complexity of data continue to expand across various scientific disciplines, the need for robust methods to account for the multiplicity of comparisons has grown widespread. A popular measure of type 1 error rate in…

统计方法学 · 统计学 2024-11-19 Jianliang He , Bowen Gang , Luella Fu

We develop a new class of distribution--free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the…

统计方法学 · 统计学 2021-05-27 Lilun Du , Xu Guo , Wenguang Sun , Changliang Zou

Controlling false discovery rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring possible…

机器学习 · 统计学 2021-01-26 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

Effectively controlling the false discovery rate (FDR) in high-dimensional variable selection is a fundamental statistical problem that has garnered significant research interest. In this paper, we propose a novel, user-friendly, and…

统计方法学 · 统计学 2026-04-28 Yujia Wu , Panxu Yuan , Binyan Jiang

False discovery rate (FDR) has been widely used as an error measure in large scale multiple testing problems, but most research in the area has been focused on procedures for controlling the FDR based on independent test statistics or the…

统计方法学 · 统计学 2009-09-29 Weihua Tang , Cun-Hui Zhang

In modern scientific experiments, we frequently encounter data that have large dimensions, and in some experiments, such high dimensional data arrive sequentially rather than full data being available all at a time. We develop multiple…

统计方法学 · 统计学 2023-06-09 Rahul Roy , Shyamal K. De , Subir Kumar Bhandari

Multivariate statistics are often available as well as necessary in hypothesis tests. We study how to use such statistics to control not only false discovery rate (FDR) but also positive FDR (pFDR) with good power. We show that FDR can be…

统计理论 · 数学 2008-05-21 Zhiyi Chi

We develop a flexible feature selection framework based on deep neural networks that approximately controls the false discovery rate (FDR), a measure of Type-I error. The method applies to architectures whose first layer is fully connected.…

机器学习 · 统计学 2026-02-10 Kazuma Sawaya

Balancing false discovery rate (FDR) control with high statistical power remains a central challenge in high-dimensional variable selection. While several FDR-controlling methods have been proposed, many degrade the original data -- by…

统计方法学 · 统计学 2025-07-16 Changhu Wang , Ziheng Zhang , Jingyi Jessica Li

The simultaneous analysis of many statistical tests is ubiquitous in applications. Perhaps the most popular error rate used for avoiding type one error inflation is the false discovery rate (FDR). However, most theoretical and software…

统计计算 · 统计学 2019-04-04 Guillermo Durand , Florian Junge , Sebastian Döhler , Etienne Roquain

This paper proposes a model-free and data-adaptive feature screening method for ultra-high dimensional datasets. The proposed method is based on the projection correlation which measures the dependence between two random vectors. This…

统计方法学 · 统计学 2021-02-16 Wanjun Liu , Yuan Ke , Jingyuan Liu , Runze Li

The horseshoe prior, a widely used handy alternative to the spike-and-slab prior, has proven to be an exceptional default global-local shrinkage prior in Bayesian inference and machine learning. However, designing tests with frequentist…

统计方法学 · 统计学 2025-02-19 Qiaoyu Liang , Zihan Zhu , Ziang Fu , Michael Evans

False discovery rate (FDR) is a common way to control the number of false discoveries in multiple testing. There are a number of approaches available for controlling FDR. However, for functional test statistics, which are discretized into…

统计方法学 · 统计学 2024-12-03 Tomáš Mrkvička , Mari Myllymäki

False discovery rates (FDR) are an essential component of statistical inference, representing the propensity for an observed result to be mistaken. FDR estimates should accompany observed results to help the user contextualize the relevance…

统计方法学 · 统计学 2020-10-12 Megan Hollister Murray , Jeffrey D. Blume

The false discovery rate (FDR)---the expected fraction of spurious discoveries among all the discoveries---provides a popular statistical assessment of the reproducibility of scientific studies in various disciplines. In this work, we…

机器学习 · 统计学 2015-11-10 Weijie Su , Junyang Qian , Linxi Liu

Testing composite null hypotheses arises in various applications, such as mediation and replicability analyses. The problem becomes more challenging in high-throughput experiments where tens of thousands of features are examined…

统计方法学 · 统计学 2025-04-29 Pengfei Lyu , Xianyang Zhang , Hongyuan Cao