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The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Functional Magnetic Resonance Imaging (fMRI) is predominantly harnessed for spatially mapping activation foci along distributed pathways. However, resolving dynamic information on activation sequence remains elusive. Here, we show an…

医学物理 · 物理学 2020-02-04 Rita Gil , Francisca F. Fernandes , Noam Shemesh

Resting-state functional magnetic resonance imaging (rsfMRI) is a powerful tool for investigating the relationship between brain function and cognitive processes as it allows for the functional organization of the brain to be captured…

机器学习 · 计算机科学 2025-02-25 Bishal Thapaliya , Esra Akbas , Jiayu Chen , Raam Sapkota , Bhaskar Ray , Pranav Suresh , Vince Calhoun , Jingyu Liu

The fetal cortical plate undergoes drastic morphological changes throughout early in utero development that can be observed using magnetic resonance (MR) imaging. An accurate MR image segmentation, and more importantly a topologically…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Priscille de Dumast , Hamza Kebiri , Chirine Atat , Vincent Dunet , Mériam Koob , Meritxell Bach Cuadra

Dementia poses a growing challenge in our aging society. Frontotemporal dementia (FTD) and Alzheimer disease (AD) are the leading causes of early-onset dementia. FTD and AD display unique traits in their onset, progression, and treatment…

信号处理 · 电气工程与系统科学 2024-09-26 Shivani Ranjan , Lalan Kumar

For multivariate data, dependence beyond pair-wise can be important. This is true, for example, in using functional MRI (fMRI) data to investigate brain functional connectivity. When one has more than a few variables, however, the number of…

统计方法学 · 统计学 2015-08-04 Steven P. Ellis , Arno Klein

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao

Sleep behavior significantly impacts health and acts as an indicator of physical and mental well-being. Monitoring and predicting sleep behavior with ubiquitous sensors may therefore assist in both sleep management and tracking of related…

机器学习 · 计算机科学 2024-01-30 Maryam Khalid , Elizabeth B. Klerman , Andrew W. Mchill , Andrew J. K. Phillips , Akane Sano

The available evidence suggests that dynamic functional connectivity (dFC) can capture time-varying abnormalities in brain activity in resting-state cerebral functional magnetic resonance imaging (rs-fMRI) data and has a natural advantage…

神经元与认知 · 定量生物学 2023-09-13 Cheng Zhu , Ying Tan , Shuqi Yang , Jiaqing Miao , Jiayi Zhu , Huan Huang , Dezhong Yao , Cheng Luo

Over the past two decades, complex network theory provided the ideal framework for investigating the intimate relationships between the topological properties characterizing the wiring of connections among a system's unitary components and…

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

神经元与认知 · 定量生物学 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Loss of cortical integration and changes in the dynamics of electrophysiological brain signals characterize the transition from wakefulness towards unconsciousness. The common mechanism underlying these observations remains unknown. In this…

Although numerous studies report significant sex differences in functional connectivity, these differences do not sufficient to reveal specific functional disparities among brain regions or the topological differences in brain networks.…

定量方法 · 定量生物学 2024-10-10 Wenyu Chen , Ling Zhan , Yunsong Luo , Jiang Qiu , Tao Jia

The global functional brain network (graph) is more suitable for characterizing brain states than local analysis of the connectivity of brain regions. Therefore, graph-theoretic approaches are the natural methods to study the brain.…

统计方法学 · 统计学 2015-12-22 André Fujita , Daniel Yasumasa Takahashi , Joana Bisol Balardin , João Ricardo Sato

The interplay between circadian and reward function is well understood in animal models, and is of growing interest as an aetiological explanation in psychopathologies. Circadian modulation of reward function has been demonstrated in human…

神经元与认知 · 定量生物学 2018-12-12 Greg Murray , Catherine Orr , Jamie E. M. Byrne , Matthew E. Hughes , Susan L. Rossell , Sheri L. Johnson

A biophysical model of arousal dynamics is used to study mechanisms of synchronisation and loss of synchrony among the three key oscillators controlling sleep-wake cycles: the circadian, homeostatic, and light oscillators. Synchronisation…

生物物理 · 物理学 2021-01-22 Dmitry E. Postnov , Ksenia O. Merkulova , Svetlana Postnova

The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain…

神经元与认知 · 定量生物学 2023-10-30 Qiang Li , Vince D. Calhoun , Adithya Ram Ballem , Shujian Yu , Jesus Malo , Armin Iraji

Objective: We aimed to determine the relationship between day-to-day sleep efficiency variability and cognitive function among older adults using accelerometer data and three cognitive tests. Methods: Older adults aged 65+ with 5 days of…

应用统计 · 统计学 2023-11-07 Collin Sakal , Tingyou Li , Juan Li , Xinyue Li
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