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The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

应用统计 · 统计学 2021-04-15 Claire Donnat , Susan Holmes

The beta model is the most important distribution for fitting data with the unit interval. However, the beta distribution is not suitable to model bimodal unit interval data. In this paper, we propose a bimodal beta distribution constructed…

统计方法学 · 统计学 2021-08-19 Roberto Vila , Lucas Alfaia , André F. B. Menezes , Mehmet N. Çankaya , Marcelo Bourguignon

This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of…

Epidemiological models contain a set of parameters that must be adjusted based on available observations. Once a model has been calibrated, it can be used as a forecasting tool to make predictions and to evaluate contingency plans. It is…

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

种群与进化 · 定量生物学 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc.…

应用统计 · 统计学 2026-02-10 Donghui Yan , Aiyou Chen , Buqing Yang

We present a new non-parametric estimator of the conditional density of the kernel type. It is based on an efficient transformation of the data by quantile transform. By use of the copula representation, it turns out to have a remarkable…

统计方法学 · 统计学 2008-06-13 Olivier P. Faugeras

We propose a high dimensional Bayesian inference framework for learning heterogeneous dynamics of a COVID-19 model, with a specific application to the dynamics and severity of COVID-19 inside and outside long-term care (LTC) facilities. We…

统计方法学 · 统计学 2021-08-04 Peng Chen , Keyi Wu , Omar Ghattas

We propose a new method for estimating the extreme quantiles for a function of several dependent random variables. In contrast to the conventional approach based on extreme value theory, we do not impose the condition that the tail of the…

统计方法学 · 统计学 2013-11-25 Jinguo Gong , Yadong Li , Liang Peng , Qiwei Yao

The analysis of complex longitudinal data such as COVID-19 deaths is challenging due to several inherent features: (i) Similarly-shaped profiles with different decay patterns; (ii) Unexplained variation among repeated measurements within…

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

其他定量生物学 · 定量生物学 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

We develop a maximum-likelihood based method for regression in a setting where the dependent variable is a random graph and covariates are available on a graph-level. The model generalizes the well-known $\beta$-model for random graphs by…

统计方法学 · 统计学 2017-05-24 Johan Wahlström , Isaac Skog , Patricio S. La Rosa , Peter Händel , Arye Nehorai

Estimating the structures at high or low quantiles has become an important subject and attracted increasing attention across numerous fields. However, due to data sparsity at tails, it usually is a challenging task to obtain reliable…

统计方法学 · 统计学 2021-11-08 Yingying Zhang , Yuefeng Si , Guodong Li , Chil-Ling Tsai

Classical epidemiological models assume homogeneous populations. There have been important extensions to model heterogeneous populations, when the identity of the sub-populations is known, such as age group or geographical location. Here,…

机器学习 · 计算机科学 2023-02-10 Roberto Vega , Zehra Shah , Pouria Ramazi , Russell Greiner

We propose novel estimators for categorical and continuous treatments by using an optimal covariate balancing strategy for inverse probability weighting. The resulting estimators are shown to be consistent and asymptotically normal for…

统计方法学 · 统计学 2025-09-08 Seong-ho Lee , Yanyuan Ma , Xavier de Luna

The cumulative incidence is the probability of failure from the cause of interest over a certain time period in the presence of other risks. A semiparametric regression model proposed by Fine and Gray (1999) has become the method of choice…

统计方法学 · 统计学 2016-03-02 Lu Mao , D. Y. Lin

The ultimate goal of regression analysis is to obtain information about the conditional distribution of a response given a set of explanatory variables. This goal is, however, seldom achieved because most established regression models only…

统计方法学 · 统计学 2017-12-13 Torsten Hothorn , Thomas Kneib , Peter Bühlmann

The need to forecast COVID-19 related variables continues to be pressing as the epidemic unfolds. Different efforts have been made, with compartmental models in epidemiology and statistical models such as AutoRegressive Integrated Moving…

应用统计 · 统计学 2020-10-07 Bahman Rostami-Tabar , Juan F. Rendon-Sanchez

Conditional quantiles provide a natural tool for reporting results from regression analyses based on semiparametric transformation models. We consider their estimation and construction of confidence sets in the presence of censoring.

统计理论 · 数学 2007-06-13 Dorota M. Dabrowska