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We present a simple and effective method to eliminate system aberrations and speckle noise in quantitative phase imaging. Using spiral integration, complete information about system aberration is calculated from three laterally shifted…

生物物理 · 物理学 2018-02-14 Inhyeok Choi , Kyeoreh Lee , YongKeun Park

Histopathology whole slide images (WSIs) can reveal significant inter-hospital variability such as illumination, color or optical artifacts. These variations, caused by the use of different scanning protocols across medical centers…

计算机视觉与模式识别 · 计算机科学 2022-07-01 Marin Scalbert , Maria Vakalopoulou , Florent Couzinié-Devy

Compressive imaging is an emerging application of compressed sensing, devoted to acquisition, encoding and reconstruction of images using random projections as measurements. In this paper we propose a novel method to provide a scalable…

信息论 · 计算机科学 2013-10-07 Diego Valsesia , Enrico Magli

Open-set 3D macromolecule detection in cryogenic electron tomography eliminates the need for target-specific model retraining. However, strict VRAM constraints prohibit processing an entire 3D tomogram, forcing current methods to rely on…

计算机视觉与模式识别 · 计算机科学 2026-05-04 Ming-Yang Ho , Alberto Bartesaghi

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

The difficulty of processing gigapixel whole slide images (WSIs) in clinical microscopy has been a long-standing barrier to implementing computer aided diagnostic systems. Since modern computing resources are unable to perform computations…

计算机视觉与模式识别 · 计算机科学 2020-08-13 Sam Maksoud , Kun Zhao , Peter Hobson , Anthony Jennings , Brian Lovell

One of the challenges facing the adoption of digital pathology workflows for clinical use is the need for automated quality control. As the scanners sometimes determine focus inaccurately, the resultant image blur deteriorates the scanned…

图像与视频处理 · 电气工程与系统科学 2018-11-16 Mahdi S. Hosseini , Yueyang Zhang , Lyndon Chan , Konstantinos N. Plataniotis , Jasper A. Z. Brawley-Hayes , Savvas Damaskinos

Time-resolved scanning near-field optical microscopy (tr-SNOM) enables the measurement of the dynamic optical response of functional surfaces beyond the diffraction limit. Experimental challenges are imposed both by the use of a pulsed…

光学 · 物理学 2026-04-16 Philipp Schwendke , Julia Stähler , Samuel Palato

Transient Photoluminescence Microscopy (TPLM) allows for the direct visualization of carrier transport in semiconductor materials with sub nanosecond and few nanometer resolution. The technique is based on measuring changes in the spatial…

We introduce a phase imaging mechanism for scanning transmission electron microscopy that exploits the complementary intensity changes of transmitted disks at different scattering angles. For scanning transmission electron microscopy, this…

仪器与探测器 · 物理学 2023-07-06 Binbin Wang , David W. McComb

Diffusion models are the current state-of-the-art for solving inverse problems in imaging. Their impressive generative capability allows them to approximate sampling from a prior distribution, which alongside a known likelihood function…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Samuel W. Remedios , Zhangxing Bian , Shuwen Wei , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

医学物理 · 物理学 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

We introduce a novel reflection-mode diffraction tomography technique that enables simultaneous recovery of forward and backward scattering information for high-resolution 3D refractive index reconstruction. Our technique works by imaging a…

光学 · 物理学 2025-02-12 Tongyu Li , Jiabei Zhu , Yi Shen , Lei Tian

A widely tested approach to overcoming the diffraction limit in microscopy without disturbing the sample relies on substituting widefield sample illumination with a structured light beam. This gives rise to confocal, image-scanning and…

光学 · 物理学 2024-06-03 Alexander Duplinskiy , Jernej Frank , Kaden Bearne , A. I. Lvovsky

Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive…

计算机视觉与模式识别 · 计算机科学 2023-01-03 Shizhan Gong , Cheng Chen , Yuqi Gong , Nga Yan Chan , Wenao Ma , Calvin Hoi-Kwan Mak , Jill Abrigo , Qi Dou

Recent developments in stimulated emission depletion (STED) microscopy achieved nanometer scale resolution and showed great potential in live cell imaging. Yet, STED nanoscopy techniques are based on single point-scanning. This constitutes…

生物物理 · 物理学 2015-06-16 Bin Yang , Frédéric Przybilla , Michael Mestre , Jean-Baptiste Trebbia , Brahim Lounis

Diffusion-based image translation guided by semantic texts or a single target image has enabled flexible style transfer which is not limited to the specific domains. Unfortunately, due to the stochastic nature of diffusion models, it is…

计算机视觉与模式识别 · 计算机科学 2023-02-02 Gihyun Kwon , Jong Chul Ye

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Optical sensing is one of the key-enablers of modern diagnostics. Especially label-free imaging modalities hold great promise as they eliminate labeling procedures prior to analysis. However, scattering signals of nanometric particles scale…

光学 · 物理学 2021-02-03 Unai Ortiz-Orruño , Ala Jo , Hakho Lee , Niek F. van Hulst , Matz Liebel