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Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…

The simultaneous application of multiple treatments is increasingly common in many fields, such as healthcare and marketing. In such scenarios, it is important to estimate the single treatment effects and the interaction treatment effects…

In the fight against the COVID-19 pandemic, leveraging artificial intelligence to predict disease outcomes from chest radiographic images represents a significant scientific aim. The challenge, however, lies in the scarcity of large,…

Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Many real-world problems exhibit the coexistence of multiple types of heterogeneity, such as view heterogeneity (i.e., multi-view property) and task heterogeneity (i.e., multi-task property). For example, in an image classification problem…

Cardiovascular diseases (CVD) and depression exhibit significant comorbidity, which is highly predictive of poor clinical outcomes. Yet, the underlying biological pathways remain challenging to decipher, presumably due to the non-linear…

Melanoma is considered to be the most aggressive form of skin cancer. Due to the similar shape of malignant and benign cancerous lesions, doctors spend considerably more time when diagnosing these findings. At present, the evaluation of…

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Radiologists interpret mammography exams by jointly analyzing all four views, as correlations among them are crucial for accurate diagnosis. Recent methods employ dedicated fusion blocks to capture such dependencies, but these are often…

A fundamental challenge in federated learning lies in mixing heterogeneous datasets and classification tasks while minimizing the high communication cost caused by clients as well as the exchange of weight updates with the server over a…