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Finding the most likely path to a set of failure states is important to the analysis of safety-critical systems that operate over a sequence of time steps, such as aircraft collision avoidance systems and autonomous cars. In many…

In this paper we consider two-stage adaptive dose-response study designs, where the study design is changed at an interim analysis based on the information collected so far. In a simulation study, two approaches will be compared for these…

统计方法学 · 统计学 2016-02-08 Emma McCallum , Björn Bornkamp

Conformal prediction is a powerful distribution-free tool for uncertainty quantification, establishing valid prediction intervals with finite-sample guarantees. To produce valid intervals which are also adaptive to the difficulty of each…

机器学习 · 计算机科学 2023-02-24 Nabeel Seedat , Alan Jeffares , Fergus Imrie , Mihaela van der Schaar

Contrastive representation learning has been recently proved to be very efficient for self-supervised training. These methods have been successfully used to train encoders which perform comparably to supervised training on downstream…

机器学习 · 计算机科学 2020-12-03 Ibrahim Merad , Yiyang Yu , Emmanuel Bacry , Stéphane Gaïffas

With the escalated demand of human-machine interfaces for intelligent systems, development of gaze controlled system have become a necessity. Gaze, being the non-intrusive form of human interaction, is one of the best suited approach.…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Somsukla Maiti , Akshansh Gupta

In adaptive clinical trials, the conventional end-of-trial point estimate of a treatment effect is prone to bias, that is, a systematic tendency to deviate from its true value. As stated in recent FDA guidance on adaptive designs, it is…

Modality representation learning is an important problem for multimodal sentiment analysis (MSA), since the highly distinguishable representations can contribute to improving the analysis effect. Previous works of MSA have usually focused…

多媒体 · 计算机科学 2023-01-31 Peipei Liu , Xin Zheng , Hong Li , Jie Liu , Yimo Ren , Hongsong Zhu , Limin Sun

We develop a unified $L$-statistic testing framework for high-dimensional regression coefficients that adapts to unknown sparsity. The proposed statistics rank coordinate-wise evidence measures and aggregate the top $k$ signals, bridging…

应用统计 · 统计学 2026-02-10 Ping Zhao , Fengyi Song , Huifang Ma

Adaptive experiments use preliminary analyses of the data to inform further course of action and are commonly used in many disciplines including medical and social sciences. Because the null hypothesis and experimental design are…

统计方法学 · 统计学 2026-05-26 Tobias Freidling , Qingyuan Zhao , Zijun Gao

The ability to accurately predict the contrast achieved from high contrast imagers is important for efficient scheduling and quality control measures in modern observatories. We aim to consistently predict and measure the raw contrast…

天体物理仪器与方法 · 物理学 2023-12-06 Benjamin Courtney-Barre , Robert De Rosa , Rosita Kokotanekova , Cristian Romero , Matias Jones , Julien Milli , Zahed Wahhaj

Adapting the final sample size of a trial to the evidence accruing during the trial is a natural way to address planning uncertainty. Designs with adaptive sample size need to account for their optional stopping to guarantee strict type-I…

Planning empirical experiments such as clinical trials or A/B tests requires sample size determination, which in many interesting cases has no closed-form solution (e.g. factorial or adaptive designs). adsasi is a new R package that enables…

统计方法学 · 统计学 2026-04-16 Skerdi Haviari

Regression on observational data can fail to capture a causal relationship in the presence of unobserved confounding. Confounding strength measures this mismatch, but estimating it requires itself additional assumptions. A common assumption…

Classic adaptive designs for time-to-event trials are based on the log-rank statistic and its increments. Thereby, only information from the time-to-event endpoint on which the selected log-rank statistic is based may be used for…

统计方法学 · 统计学 2025-09-03 Rene Schmidt , Moritz Fabian Danzer

The comparison of different medical treatments from observational studies or across different clinical studies is often biased by confounding factors such as systematic differences in patient demographics or in the inclusion criteria for…

统计方法学 · 统计学 2025-05-15 Ekkehard Glimm , Lillian Yau

In regression problems where covariates can be naturally grouped, the group Lasso is an attractive method for variable selection since it respects the grouping structure in the data. We study the selection and estimation properties of the…

统计理论 · 数学 2010-11-30 Fengrong Wei , Jian Huang

We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive…

医学物理 · 物理学 2012-02-16 Jagdish Ramakrishnan , David Craft , Thomas Bortfeld , John N. Tsitsiklis

We propose Adaptive Randomized Smoothing (ARS) to certify the predictions of our test-time adaptive models against adversarial examples. ARS extends the analysis of randomized smoothing using $f$-Differential Privacy to certify the adaptive…

机器学习 · 计算机科学 2025-07-11 Saiyue Lyu , Shadab Shaikh , Frederick Shpilevskiy , Evan Shelhamer , Mathias Lécuyer

Dose-response models express the effect of different dose or exposure levels on a specific outcome. In meta-analysis, where aggregated-level data is available, dose-response evidence is synthesized using either one-stage or two-stage models…

Supervised learning can improve the design of state-of-the-art solvers for combinatorial problems, but labelling large numbers of combinatorial instances is often impractical due to exponential worst-case complexity. Inspired by the recent…

机器学习 · 计算机科学 2022-06-22 Haonan Duan , Pashootan Vaezipoor , Max B. Paulus , Yangjun Ruan , Chris J. Maddison
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