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Multimodal Large Language Models (MLLMs) are set to transform how machines process and generate human-like responses by integrating diverse modalities such as text, images, and code. Yet, effectively harnessing their capabilities hinges on…

人工智能 · 计算机科学 2025-04-15 Anwesha Mohanty , Venkatesh Balavadhani Parthasarathy , Arsalan Shahid

Predicting whether a molecule can cross the blood-brain barrier (BBB) is a key step in early-stage neuro-pharmaceutical design, directly influencing the efficiency and success rate of drug development. Traditional methods based on…

定量方法 · 定量生物学 2026-03-16 Zihan Yang , Yuchen Xiao

Large language model (LLM) evaluation is increasingly costly, prompting interest in methods that speed up evaluation by shrinking benchmark datasets. Benchmark prediction (also called efficient LLM evaluation) aims to select a small subset…

机器学习 · 计算机科学 2025-06-10 Guanhua Zhang , Florian E. Dorner , Moritz Hardt

Computational cognitive models, which formalize theories of cognition, enable researchers to quantify cognitive processes and arbitrate between competing theories by fitting models to behavioral data. Traditionally, these models are…

机器学习 · 计算机科学 2025-11-10 Milena Rmus , Akshay K. Jagadish , Marvin Mathony , Tobias Ludwig , Eric Schulz

Cardiovascular disease is one of the chronic diseases that is on the rise. The complications occur when cardiovascular disease is not discovered early and correctly diagnosed at the right time. Various machine learning approaches, including…

Mammalian whole-brain connectomes are a foundational ingredient for holistic understanding of brains. Indeed, imaging connectomes at sufficient resolution to densely reconstruct cellular morphology and synapses represents a longstanding…

神经元与认知 · 定量生物学 2025-02-03 Logan Thrasher Collins , Todd Huffman , Randal Koene

We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

机器学习 · 计算机科学 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

Machine learning (ML) is revolutionising drug discovery by expediting the prediction of small molecule properties essential for developing new drugs. These properties -- including absorption, distribution, metabolism and excretion (ADME)--…

机器学习 · 计算机科学 2024-08-02 Alex G. C. de Sá , David B. Ascher

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

神经元与认知 · 定量生物学 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

机器学习 · 计算机科学 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

人工智能 · 计算机科学 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Online learning and MOOCs have become increasingly popular in recent years, and the trend will continue, given the technology boom. There is a dire need to observe learners' behavior in these online courses, similar to what instructors do…

机器学习 · 计算机科学 2023-12-29 Aditya Panwar , Ashwin T S , Ramkumar Rajendran , Kavi Arya

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

神经元与认知 · 定量生物学 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Converging evidence shows that disease-relevant brain alterations do not appear in random brain locations, instead, its spatial pattern follows large scale brain networks. In this context, a powerful network analysis approach with a…

Brain connectivity analysis based on magnetic resonance imaging is crucial for understanding neurological mechanisms. However, edge-based connectivity inference faces significant challenges, particularly the curse of dimensionality when…

统计方法学 · 统计学 2025-12-23 Zijing Li , Chenhao Zeng , Shufei Ge

A great deal of effort has been devoted to discovering a particular genetic disorder, but its classification across a broad spectrum of disorder classes and types remains elusive. Early diagnosis of genetic disorders enables timely…

人工智能 · 计算机科学 2024-12-04 Abu Bakar Siddik , Faisal R. Badal , Afroza Islam

Automating machine learning has achieved remarkable technological developments in recent years, and building an automated machine learning pipeline is now an essential task. The model ensemble is the technique of combining multiple models…

机器学习 · 计算机科学 2022-07-21 Yunpu Zhao , Rui Zhang , Xiaqing Li

We consider the problem of predicting link formation in Social Learning Networks (SLN), a type of social network that forms when people learn from one another through structured interactions. While link prediction has been studied for…

社会与信息网络 · 计算机科学 2023-01-05 Rajeev Sahay , Serena Nicoll , Minjun Zhang , Tsung-Yen Yang , Carlee Joe-Wong , Kerrie A. Douglas , Christopher G Brinton

Active Queue Management (AQM), a network-layer congestion control technique endorsed by the Internet Engineering Task Force (IETF), encourages routers to discard packets before the occurrence of buffer overflow. Traditional AQM techniques…

网络与互联网体系结构 · 计算机科学 2024-10-04 Mohammad Parsa Toopchinezhad , Mahmood Ahmadi

Deep-learning models such as Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) have been successfully used for process-mining tasks. They have achieved better performance for different predictive tasks than traditional…

机器学习 · 计算机科学 2021-05-04 Ishwar Venugopal , Jessica Töllich , Michael Fairbank , Ansgar Scherp