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Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

{Introduction: } Dementia is a neurological disorder associated with aging that can cause a loss of cognitive functions, impacting daily life. Alzheimer's disease (AD) is the most common cause of dementia, accounting for 50--70\% of cases,…

神经元与认知 · 定量生物学 2023-11-07 Zaineb Ajra , Binbin Xu , Gérard Dray , Jacky Montmain , Stéphane Perrey

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

计算机视觉与模式识别 · 计算机科学 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

计算与语言 · 计算机科学 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

医学物理 · 物理学 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

神经元与认知 · 定量生物学 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care to delay further progression. This paper presents the development of a state-of-the-art Conformer based speech recognition system built on the…

音频与语音处理 · 电气工程与系统科学 2022-06-28 Tianzi Wang , Jiajun Deng , Mengzhe Geng , Zi Ye , Shoukang Hu , Yi Wang , Mingyu Cui , Zengrui Jin , Xunying Liu , Helen Meng

Early diagnosis of Alzheimer's Disease (AD), particularly at the mild cognitive impairment stage, is essential for timely intervention. However, this process faces significant barriers, including reliance on subjective assessments and the…

计算机视觉与模式识别 · 计算机科学 2025-12-19 Changwei Wu , Yifei Chen , Yuxin Du , Jinying Zong , Jie Dong , Mingxuan Liu , Feiwei Qin , Yong Peng , Jin Fan , Changmiao Wang

In recent years there has been a burgeoning interest in the use of computational methods to distinguish between elicited speech samples produced by patients with dementia, and those from healthy controls. The difference between perplexity…

计算与语言 · 计算机科学 2020-06-30 Trevor Cohen , Serguei Pakhomov

Alzheimer's Disease (AD), as the most devastating neurodegenerative disease worldwide, has reached nearly 10 million new cases annually. Current technology provides unprecedented opportunities to study the progression and etiology of this…

神经元与认知 · 定量生物学 2022-11-14 Zibin Zhao

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

图像与视频处理 · 电气工程与系统科学 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers. However, to…

机器学习 · 计算机科学 2021-09-28 Raphael Ronge , Kwangsik Nho , Christian Wachinger , Sebastian Pölsterl

Alzheimer's disease is a neurogenerative disease that alters memories, cognitive functions leading to death. Early diagnosis of the disease, by detection of the preliminary stage, called Mild Cognitive Impairment (MCI), remains a…

图像与视频处理 · 电气工程与系统科学 2020-12-03 Achraf Ben Miled , Taoufik Yeferny , Amira ben Rabeh

Alzheimer's disease (AD) causes alterations of brain network structure and function. The latter consists of connectivity changes between oscillatory processes at different frequency channels. We proposed a multi-layer network approach to…

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

机器学习 · 计算机科学 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Alzheimer's Disease (AD) is a progressive neurodegenerative condition that adversely affects cognitive abilities. Language-related changes can be automatically identified through the analysis of outputs from linguistic assessment tasks,…

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

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