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Unraveling the co-expression of genes across studies enhances the understanding of cellular processes. Inferring gene co-expression networks from transcriptome data presents many challenges, including spurious gene correlations, sample…

机器学习 · 统计学 2024-10-01 Teodora Pandeva , Martijs Jonker , Leendert Hamoen , Joris Mooij , Patrick Forré

The paper introduces a generalization for known probabilistic models such as log-linear and graphical models, called here multiplicative models. These models, that express probabilities via product of parameters are shown to capture…

人工智能 · 计算机科学 2012-06-18 Ydo Wexler , Christopher Meek

Linear structural equation models, which relate random variables via linear interdependencies and Gaussian noise, are a popular tool for modeling multivariate joint distributions. These models correspond to mixed graphs that include both…

统计计算 · 统计学 2015-04-14 Mathias Drton , Luca Weihs

Graph neural networks are increasingly applied to multimodal medical diagnosis for their inherent relational modeling capabilities. However, their efficacy is often compromised by the prevailing reliance on a single, static graph built from…

计算机视觉与模式识别 · 计算机科学 2025-12-24 Ziwei Qin , Xuhui Song , Deqing Huang , Na Qin , Jun Li

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

机器学习 · 计算机科学 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Promising results have driven a recent surge of interest in continuous optimization methods for Bayesian network structure learning from observational data. However, there are theoretical limitations on the identifiability of underlying…

Heterogeneous molecular entities and their interactions, commonly depicted as a network, are crucial for advancing our systems-level understanding of biology. With recent advancements in high-throughput data generation and a significant…

定量方法 · 定量生物学 2026-03-18 Kishan KC , Rui Li , Paribesh Regmi , Anne R. Haake

In the presented work, we propose to apply the framework of graph neural networks (GNNs) to predict the dynamics of a rolling element bearing. This approach offers generalizability and interpretability, having the potential for scalable use…

机器学习 · 计算机科学 2023-09-20 Vinay Sharma , Jens Ravesloot , Cees Taal , Olga Fink

Reducing a graph while preserving its overall properties is an important problem with many applications. Typically, reduction approaches either remove edges (sparsification) or merge nodes (coarsening) in an unsupervised way with no…

机器学习 · 计算机科学 2025-04-09 Maria Bånkestad , Jennifer R. Andersson , Sebastian Mair , Jens Sjölund

A central question in neuroscience is how self-organizing dynamic interactions in the brain emerge on their relatively static structural backbone. Due to the complexity of spatial and temporal dependencies between different brain areas,…

The deep learning framework is witnessing expansive growth into diverse applications such as biological systems, human cognition, robotics, and the social sciences, thanks to its immense ability to extract essential features from…

无序系统与神经网络 · 物理学 2017-10-16 Zhaocheng Liu , Sean P. Rodrigues , Wenshan Cai

This paper studies causal inference with observational data from a single large network. We consider a nonparametric model with interference in both potential outcomes and selection into treatment. Specifically, both stages may be the…

计量经济学 · 经济学 2025-12-30 Michael P. Leung , Pantelis Loupos

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

种群与进化 · 定量生物学 2014-12-10 Benedikt Obermayer , Erel Levine

Time series forecasting is an extensively studied subject in statistics, economics, and computer science. Exploration of the correlation and causation among the variables in a multivariate time series shows promise in enhancing the…

机器学习 · 计算机科学 2021-04-22 Chao Shang , Jie Chen , Jinbo Bi

A wide range of models have been proposed for Graph Generative Models, necessitating effective methods to evaluate their quality. So far, most techniques use either traditional metrics based on subgraph counting, or the representations of…

机器学习 · 统计学 2022-06-14 Hamed Shirzad , Kaveh Hassani , Danica J. Sutherland

We propose an efficient algorithm to visualise symmetries in neural networks. Typically, models are defined with respect to a parameter space, where non-equal parameters can produce the same input-output map. Our proposed method, GENNI,…

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

统计方法学 · 统计学 2016-06-09 Mathias Drton , Marloes H. Maathuis

Interacting systems are prevalent in nature, from dynamical systems in physics to complex societal dynamics. The interplay of components can give rise to complex behavior, which can often be explained using a simple model of the system's…

机器学习 · 统计学 2018-06-07 Thomas Kipf , Ethan Fetaya , Kuan-Chieh Wang , Max Welling , Richard Zemel

Data imputation is an effective way to handle missing data, which is common in practical applications. In this study, we propose and test a novel data imputation process that achieve two important goals: (1) preserve the row-wise…

机器学习 · 计算机科学 2023-09-13 Katrina Chen , Xiuqin Liang , Zheng Ma , Zhibin Zhang

Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the…

基因组学 · 定量生物学 2015-04-09 Andrew L. Beam , Alison Motsinger-Reif , Jon Doyle