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Understanding associations between paired high-dimensional longitudinal datasets is a fundamental yet challenging problem that arises across scientific domains, including longitudinal multi-omic studies. The difficulty stems from the…

统计方法学 · 统计学 2026-01-21 Jianbin Tan , Pixu Shi

Predictive modeling plays key role in providing accurate prognosis and enables us to take a step closer to personalized treatment. We identified two potential sources of human induced biases that can lead to disparate conclusions. We…

应用统计 · 统计学 2017-02-08 Madhuchhanda Bhattacharjee

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

We introduce a novel recurrent neural network (RNN) approach to account for temporal dynamics and dependencies in brain networks observed via functional magnetic resonance imaging (fMRI). Our approach directly parameterizes temporal…

神经与进化计算 · 计算机科学 2018-08-28 R Devon Hjelm , Eswar Damaraju , Kyunghyun Cho , Helmut Laufs , Sergey M. Plis , Vince Calhoun

Data-driven methods are emerging as efficient alternatives to traditional numerical forecasting, offering fast inference and lower computational cost. Yet, for complex systems, long-term accuracy often deteriorates due to error…

机器学习 · 计算机科学 2025-09-03 Hao Zhou , Sibo Cheng

A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different brain states is…

神经元与认知 · 定量生物学 2018-09-26 Enrico Amico , Alex Arenas , Joaquin Goni

Functional data analysis, which models data as realizations of random functions over a continuum, has emerged as a useful tool for time series data. Often, the goal is to infer the dynamic connections (or time-varying conditional…

统计方法学 · 统计学 2024-12-10 Chunshan Liu , Daniel R. Kowal , James Doss-Gollin , Marina Vannucci

Dynamic functional connectivity (dFC) is ubiquitously observed in the brain, but why functional networks should remain dynamic even at rest is unclear. We asked whether temporal reconfiguration becomes advantageous when keeping a functional…

生物物理 · 物理学 2026-04-14 Simachew Abebe Mengiste , Demian Battaglia

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

应用统计 · 统计学 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Building comprehensive brain connectomes has proved of fundamental importance in resting-state fMRI (rs-fMRI) analysis. Based on the foundation of brain network, spatial-temporal-based graph convolutional networks have dramatically improved…

机器学习 · 计算机科学 2023-12-19 Rui Yang , Wenrui Dai , Huajun She , Yiping P. Du , Dapeng Wu , Hongkai Xiong

Accurate prediction of spatially dependent functional data is critical for various engineering and scientific applications. In this study, a spatial functional deep neural network model was developed with a novel non-linear modeling…

统计方法学 · 统计学 2025-04-18 Merve Basaran , Ufuk Beyaztas , Han Lin Shang , Zaher Mundher Yaseen

This paper explores how large language models can leverage multi-level contextual information to predict group coordination patterns in collaborative mixed reality environments. We demonstrate that encoding individual behavioral profiles,…

人机交互 · 计算机科学 2025-11-19 Diana Romero , Xin Gao , Daniel Khalkhali , Salma Elmalaki

This work studies the entity-wise topical behavior from massive network logs. Both the temporal and the spatial relationships of the behavior are explored with the learning architectures combing the recurrent neural network (RNN) and the…

机器学习 · 计算机科学 2017-05-04 Shih-Chieh Su

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Deep learning methods achieve remarkable predictive performance in modeling complex, large-scale data. However, assessing the quality of derived models has become increasingly challenging, as more classical statistical assumptions may no…

机器学习 · 统计学 2026-03-02 Daniele Zambon , Cesare Alippi

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Integrating intelligent systems, such as robots, into dynamic group settings poses challenges due to the mutual influence of human behaviors and internal states. A robust representation of social interaction dynamics is essential for…

人机交互 · 计算机科学 2024-06-11 J. Taery Kim , Archit Naik , Isuru Jayarathne , Sehoon Ha , Jouh Yeong Chew

Behavior prediction based on historical behavioral data have practical real-world significance. It has been applied in recommendation, predicting academic performance, etc. With the refinement of user data description, the development of…

机器学习 · 计算机科学 2023-09-27 Haobing Liu , Yanmin Zhu , Chunyang Wang , Jianyu Ding , Jiadi Yu , Feilong Tang

The brain's structural connectome supports signal propagation between neuronal elements, shaping diverse coactivation patterns that can be captured as functional connectivity. While the link between structure and function remains an ongoing…

神经元与认知 · 定量生物学 2022-07-11 Yaqian Yang , Zhiming Zheng , Longzhao Liu , Hongwei Zheng , Yi Zhen , Yi Zheng , Xin Wang , Shaoting Tang

This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

机器学习 · 计算机科学 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao