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We introduce a tensor-based clustering method to extract sparse, low-dimensional structure from high-dimensional, multi-indexed datasets. This framework is designed to enable detection of clusters of data in the presence of structural…

定量方法 · 定量生物学 2019-02-11 Anna Seigal , Mariano Beguerisse-Díaz , Birgit Schoeberl , Mario Niepel , Heather A. Harrington

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

应用统计 · 统计学 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

统计计算 · 统计学 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

Cancer has become one of the most widespread diseases in the world. Specifically, breast cancer is diagnosed more often than any other type of cancer. However, breast cancer patients and their individual tumors are often unique. Identifying…

定量方法 · 定量生物学 2016-12-06 Chenzhe Qian

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

机器学习 · 统计学 2015-12-01 Eric F. Lock , David B. Dunson

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…

机器学习 · 统计学 2023-10-20 Dimitrios Saligkaras , Vasileios E. Papageorgiou

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

统计方法学 · 统计学 2025-07-22 Kazeem Kareem , Fan Dai

Breast cancer is a significant global health issue, and the diagnosis of breast cancer through imaging remains challenging. Mammography images are characterized by extremely high resolution, while lesions often occupy only a small portion…

组织与器官 · 定量生物学 2025-07-28 Shilong Yang , Chulong Zhang , Xiaokun Liang , Qi Zang , Juan Yu , Liang Zeng , Xiao Luo , Yexuan Xing , Xin Pan , Qi Li , Linlin Shen , Yaoqin Xie

This paper presents a comprehensive comparative analysis of prominent clustering algorithms K-means, DBSCAN, and Spectral Clustering on high-dimensional datasets. We introduce a novel evaluation framework that assesses clustering…

机器学习 · 计算机科学 2025-07-31 Vishnu Vardhan Baligodugula , Fathi Amsaad

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

图像与视频处理 · 电气工程与系统科学 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Clustering is a core task in machine learning with wide-ranging applications in data mining and pattern recognition. However, its unsupervised nature makes it inherently challenging. Many existing clustering algorithms suffer from critical…

机器学习 · 计算机科学 2025-07-29 Ahmed Shokry , Ayman Khalafallah

In data containing heterogeneous subpopulations, classification performance benefits from incorporating the knowledge of cluster structure in the classifier. Previous methods for such combined clustering and classification either 1) are…

机器学习 · 计算机科学 2023-01-04 Shivin Srivastava , Siddharth Bhatia , Lingxiao Huang , Lim Jun Heng , Kenji Kawaguchi , Vaibhav Rajan

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

机器学习 · 计算机科学 2023-05-05 Juan Zuluaga-Gomez

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

数据结构与算法 · 计算机科学 2015-12-01 Ka-Chun Wong

Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

机器学习 · 统计学 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…

统计方法学 · 统计学 2016-09-23 Sheila Gaynor , Eric Bair

Clustering large, mixed data is a central problem in data mining. Many approaches adopt the idea of k-means, and hence are sensitive to initialisation, detect only spherical clusters, and require a priori the unknown number of clusters. We…

机器学习 · 统计学 2020-11-13 Joshua Tobin , Mimi Zhang

Cluster analysis methods seek to partition a data set into homogeneous subgroups. It is useful in a wide variety of applications, including document processing and modern genetics. Conventional clustering methods are unsupervised, meaning…

统计方法学 · 统计学 2014-07-11 Eric Bair
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