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In histopathology, scanner-induced domain shifts are known to impede the performance of trained neural networks when tested on unseen data. Multi-domain pre-training or dedicated domain-generalization techniques can help to develop…

The MIDOG 2025 challenge extends prior work on mitotic figure detection by introducing a new Track 2 on atypical mitosis classification. This task aims to distinguish normal from atypical mitotic figures in histopathology images, a…

Change detection has essential significance for the region's development, in which pseudo-changes between bitemporal images induced by imaging environmental factors are key challenges. Existing transformation-based methods regard…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Qi Zang , Shuang Wang , Dong Zhao , Dou Quan , Yang Hu , Licheng Jiao

Image normalization is a critical step in medical imaging. This step is often done on a per-dataset basis, preventing current segmentation algorithms from the full potential of exploiting jointly normalized information across multiple…

机器学习 · 计算机科学 2020-02-04 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert

The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

计算机视觉与模式识别 · 计算机科学 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

Foundation models (FMs), i.e., models trained on a vast amount of typically unlabeled data, have become popular and available recently for the domain of histopathology. The key idea is to extract semantically rich vectors from any input…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Jonathan Ganz , Jonas Ammeling , Emely Rosbach , Ludwig Lausser , Christof A. Bertram , Katharina Breininger , Marc Aubreville

We present a solution for the MIDOG 2025 Challenge Track~2, addressing binary classification of normal mitotic figures (NMFs) versus atypical mitotic figures (AMFs). The approach leverages pathology-specific foundation model H-optimus-0,…

Atypical mitotic figures (AMFs) are clinically relevant indicators of abnormal cell division, yet their reliable detection remains challenging due to morphological ambiguity and scanner variability. In this work, we investigated three…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Biwen Meng , Xi Long , Jingxin Liu

Domain shift in digital histopathology can occur when different stains or scanners are used, during stain translation, etc. A deep neural network trained on source data may not generalise well to data that has undergone some domain shift.…

图像与视频处理 · 电气工程与系统科学 2022-05-10 Zeeshan Nisar , Jelica Vasiljević , Pierre Gançarski , Thomas Lampert

This paper addresses domain adaptation for the pixel-wise classification of remotely sensed data using deep neural networks (DNN) as a strategy to reduce the requirements of DNN with respect to the availability of training data. We focus on…

计算机视觉与模式识别 · 计算机科学 2021-08-18 Dennis Wittich , Franz Rottensteiner

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

计算机视觉与模式识别 · 计算机科学 2022-02-18 Robin Elizabeth Yancey

Domain shift refers to the well known problem that a model trained in one source domain performs poorly when applied to a target domain with different statistics. {Domain Generalization} (DG) techniques attempt to alleviate this issue by…

机器学习 · 计算机科学 2017-10-11 Da Li , Yongxin Yang , Yi-Zhe Song , Timothy M. Hospedales

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

图像与视频处理 · 电气工程与系统科学 2023-05-10 Andrew Walker

The problem of domain generalization is to take knowledge acquired from a number of related domains where training data is available, and to then successfully apply it to previously unseen domains. We propose a new feature learning…

计算机视觉与模式识别 · 计算机科学 2016-07-28 Muhammad Ghifary , W. Bastiaan Kleijn , Mengjie Zhang , David Balduzzi

This study introduces a novel framework for enhancing domain generalization in medical imaging, specifically focusing on utilizing unlabelled multi-view colour fundus photographs. Unlike traditional approaches that rely on single-view…

The well known domain shift issue causes model performance to degrade when deployed to a new target domain with different statistics to training. Domain adaptation techniques alleviate this, but need some instances from the target domain to…

机器学习 · 计算机科学 2019-06-11 Yiying Li , Yongxin Yang , Wei Zhou , Timothy M. Hospedales

Discrepancy between training and testing domains is a fundamental problem in the generalization of machine learning techniques. Recently, several approaches have been proposed to learn domain invariant feature representations through…

机器学习 · 统计学 2019-03-18 Yitong Li , Michael Murias , Samantha Major , Geraldine Dawson , David E. Carlson

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Domain adaptation is an active area of research driven by the growing demand for robust machine learning models that perform well on real-world data. Adversarial learning for deep neural networks (DNNs) has emerged as a promising approach…

计算机视觉与模式识别 · 计算机科学 2025-01-08 Eugene Choi , Julian Rodriguez , Edmund Young