相关论文: A pH-based bio-rheostat: a proof-of-concept
This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to…
Selectivity and sensitivity are important figures of merit in the design and optimization of electrochemical biosensors. The efficiency of the fabricated immunosensing surface can easily be influenced by several factors, such as detection…
We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand…
Resistive Plate Chambers (RPCs) featuring 1 mm gas volumes combined with high-pressure phenolic laminate (HPL) electrodes provide excellent timing resolution down to a few hundred picoseconds, along with spatial resolution on the order of a…
The first realization of a designed, rather than natural, biochemical filter process is reported and analyzed as a promising network component for increasing the complexity of biomolecular logic systems. Key challenge in biochemical logic…
The Integration Host Factor (IHF) is a nucleoid-associated protein critical for both DNA compaction and biofilm stability. While its role in DNA packaging within the cell is well understood, its structural role in scaffolding biofilms is…
Resistive Plate Chambers (RPCs) are gaseous detectors widely used in high energy physics experiments, operating with a gas mixture primarily containing Tetrafluoroethane (C$_{2}$H$_{2}$F$_{4}$), commonly known as R-134a, which has a global…
The development of highly-sensitive and miniaturized sensors that capable of real-time analytes detection is highly desirable. Nowadays, toxic or colorless gas detection, air pollution monitoring, harmful chemical, pressure, strain,…
Photonic crystals (PCs) with localized optical cavity modes arising from topological domain-wall line defects are simulated for optical biosensing by numerical solution of Maxwell's equations. These consist of a square lattice of square…
Resistive Plate Chambers (RPCs) are essential active media of large-scale experiments as part of the muon systems and (semi-)digital hadron calorimeters. Among the several outstanding issues associated with the RPCs, the loss of efficiency…
The interaction of light with photosynthetic proteins is an extremely efficient process and has been thoroughly investigated. However, exploring light-matter interactions in hybrid nano-solid-photosynthetic proteins is a relatively new and…
The objective of this project is to develop an automated device used to spot protein samples on a hydrophobic membrane to be used for the patented electrophoresis method developed by Chang and Yonan in 2008 [1]. This novel method performs…
The reaction dynamics for the H + HeH$^+$ $\rightarrow$ He + H$_2^+$ reaction in its electronic ground state is investigated using two different representations of the potential energy surface (PES). The first uses a combined kernel and…
The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…
Next-generation touch panels are poised to benefit from the use of stretchable and transparent soft ionic conductors, but these materials face several challenges in practical application, including structural damage, loss of functionality,…
Inspired by the classic theory, we suggest that the performance of a D-shaped fiber optical surface plasmon resonance (SPR) sensor can be improved by manipulating the fiber core mode. To demonstrate this, we propose a novel fiber SPR sensor…
Low concentration hydrogen gas detection is of paramount importance both in space applications as well as medical applications. It is also critically important for safe handling of hydrogen below the explosive limit. Here, we report a novel…
There is currently a growing interest in understanding the origins of intrinsic fluorescence as a way to design non-invasive probes for biophysical processes. In this regard, understanding how pH influences fluorescence in non-aromatic…
Bioimpedance measurements are a non-invasive method to determine the composition of organic tissue. For measuring the complex bioimpedance between two electrodes, an alternating current with a constant amplitude is injected into the tissue.…
Electrostatic interactions play a fundamental role in the structure and function of proteins. Due to ionizable amino acid residues present on the solvent-exposed surfaces of proteins, the protein charge is not constant but varies with the…