相关论文: Understanding the factors driving the opioid epide…

Estimating the number of the number of people from hidden and/or marginalised populations - such as people dependent on opioids or cocaine - is important to guide policy decisions and provision of harm reduction services. Methods such as…

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Substance abuse is the unrestrained and detrimental use of psychoactive chemical substances, unauthorized drugs, and alcohol. Continuous use of these substances can ultimately lead a human to disastrous consequences. As patients display a…

Evidence from animal models and epidemiological studies has linked prenatal alcohol exposure (PAE) to a broad range of long-term cognitive and behavioral deficits. However, there is virtually no information in the scientific literature…

The drug overdose crisis in the United States continues to intensify. Fatalities have increased five-fold since 1999 reaching a record high of 108,000 deaths in 2021. The epidemic has unfolded through distinct waves of different drug types,…

Road fatalities pose significant public safety and health challenges worldwide, with pedestrians being particularly vulnerable in vehicle-pedestrian crashes due to disparities in physical and performance characteristics. This study employs…

Drug overdose has become a public health crisis in the United States with devastating consequences. However, most of the drug overdose incidences are the consequence of recitative polysubstance usage over a defined period of time which can…

The aim of this study is to look at predicting whether a person will complete a drug and alcohol rehabilitation program and the number of times a person attends. The study is based on demographic data obtained from Substance Abuse and…

Although prediction models for delirium, a commonly occurring condition during general hospitalization or post-surgery, have not gained huge popularity, their algorithmic bias evaluation is crucial due to the existing association between…

Understanding how urban socio-demographic and environmental factors relate with health is essential for public health and urban planning. However, traditional statistical methods struggle with nonlinear effects, while machine learning…

In recent years, techniques from Topological Data Analysis (TDA) have proven effective at capturing spatial features of multidimensional data. However, applying TDA to spatiotemporal data remains relatively underexplored. In this work, we…

In many fields, populations of interest are hidden from data for a variety of reasons, though their magnitude remains important in determining resource allocation and appropriate policy. In public health and epidemiology, linkages or…

The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

County-level estimates of opioid use disorder (OUD) are essential for understanding the influence of local economic and social conditions. They provide policymakers with the granular information needed to identify, target, and implement…

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

We use high resolution data to investigate the association between crime incidence and proximity to different types of public schools over the past fifteen years in the city of Philadelphia. We employ two statistical methods, regression…

Background: Psychedelic drugs facilitate profound changes in consciousness and have potential to provide insights into the nature of human mental processes and their relation to brain physiology. Yet published scientific literature reflects…

The opioid crisis has been one of the most critical society concerns in the United States. Although the medication assisted treatment (MAT) is recognized as the most effective treatment for opioid misuse and addiction, the various side…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

Naloxone, an opioid antagonist, has been widely used to save lives from opioid overdose, a leading cause for death in the opioid epidemic. However, naloxone has short brain retention ability, which limits its therapeutic efficacy.…