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Imaging and genomic data offer distinct and rich features, and their integration can unveil new insights into the complex landscape of diseases. In this study, we present a novel approach utilizing radiogenomic data including structural MRI…

机器学习 · 计算机科学 2025-05-16 Aditya Raj , Golrokh Mirzaei

Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Ángel de la Vega Jiménez

Early diagnosis of Alzheimer's disease is a challenge because the existing methodologies do not identify the patients in their preclinical stage, which can last up to a decade prior to the onset of clinical symptoms. Several research…

机器学习 · 计算机科学 2024-01-03 Vivek Kumar Tiwari , Premananda Indic , Shawana Tabassum

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

图像与视频处理 · 电气工程与系统科学 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…

We propose to apply a 2D CNN architecture to 3D MRI image Alzheimer's disease classification. Training a 3D convolutional neural network (CNN) is time-consuming and computationally expensive. We make use of approximate rank pooling to…

计算机视觉与模式识别 · 计算机科学 2021-01-14 Xin Xing , Gongbo Liang , Hunter Blanton , Muhammad Usman Rafique , Chris Wang , Ai-Ling Lin , Nathan Jacobs

Motivation. While recent studies show high accuracy in the classification of Alzheimer's disease using deep neural networks, the underlying learned concepts have not been investigated. Goals. To systematically identify changes in brain…

Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to…

图像与视频处理 · 电气工程与系统科学 2020-12-01 Fatih Altay , Guillermo Ramon Sanchez , Yanli James , Stephen V. Faraone , Senem Velipasalar , Asif Salekin

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…

图像与视频处理 · 电气工程与系统科学 2024-01-09 Taymaz Akan , Sait Alp , Mohammad A. N Bhuiyanb

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

机器学习 · 计算机科学 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

图像与视频处理 · 电气工程与系统科学 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Audrey Paleczny , Shubham Parab , Maxwell Zhang

Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…

图像与视频处理 · 电气工程与系统科学 2022-07-06 Marla Narazani , Ignacio Sarasua , Sebastian Pölsterl , Aldana Lizarraga , Igor Yakushev , Christian Wachinger