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Graph Neural Networks (GNNs) are widely used deep learning models that learn meaningful representations from graph-structured data. Due to the finite nature of the underlying recurrent structure, current GNN methods may struggle to capture…

机器学习 · 计算机科学 2021-06-02 Fangda Gu , Heng Chang , Wenwu Zhu , Somayeh Sojoudi , Laurent El Ghaoui

COVID-19 has created a global pandemic with high morbidity and mortality in 2020. Novel coronavirus (nCoV), also known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), is responsible for this deadly disease. International…

The problem of identifying important players in a given network is of pivotal importance for viral marketing, public health management, network security and various other fields of social network analysis. In this work we find the most…

离散数学 · 计算机科学 2017-11-03 Juvaria Tariq , Muhammad Ahmad , Imdadullah Khan , Mudassir Shabbir

Protein-protein interactions (PPIs) play key roles in a broad range of biological processes. Numerous strategies have been proposed for predicting PPIs, and among them, graph-based methods have demonstrated promising outcomes owing to the…

机器学习 · 计算机科学 2024-04-19 Mingda Xu , Peisheng Qian , Ziyuan Zhao , Zeng Zeng , Jianguo Chen , Weide Liu , Xulei Yang

The investment of time and resources for better strategies and methodologies to tackle a potential pandemic is key to deal with potential outbreaks of new variants or other viruses in the future. In this work, we recreated the scene of a…

机器学习 · 计算机科学 2021-04-22 Andrés L. Suárez-Cetrulo , Ankit Kumar , Luis Miralles-Pechuán

Recurring outbreaks of COVID-19 have posed enduring effects on global society, which calls for a predictor of pandemic waves using various data with early availability. Existing prediction models that forecast the first outbreak wave using…

社会与信息网络 · 计算机科学 2022-06-13 J. Xue , T. Yabe , K. Tsubouchi , J. Ma , S. V. Ukkusuri

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

物理与社会 · 物理学 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Graphs are a powerful tool for representing and analyzing unstructured, non-Euclidean data ubiquitous in the healthcare domain. Two prominent examples are molecule property prediction and brain connectome analysis. Importantly, recent works…

机器学习 · 计算机科学 2022-04-04 Kamilia Mullakaeva , Luca Cosmo , Anees Kazi , Seyed-Ahmad Ahmadi , Nassir Navab , Michael M. Bronstein

Given a network of nodes, minimizing the spread of a contagion using a limited budget is a well-studied problem with applications in network security, viral marketing, social networks, and public health. In real graphs, virus may infect a…

离散数学 · 计算机科学 2017-11-03 Muhammad Ahmad , Juvaria Tariq , Mudassir Shabbir , Imdadullah Khan

Graph neural networks (GNNs) are increasingly used to model biological systems, yet the reliability of post-hoc explanation methods for recovering meaningful molecular mechanisms remains unclear. Here, we systematically evaluate four widely…

分子网络 · 定量生物学 2026-05-22 Kyle Higgins , Ivan Laponogov , Dennis Veselkov , Kirill Veselkov

Background: Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily…

机器学习 · 计算机科学 2024-06-11 Xinyue Hu , Zenan Sun , Yi Nian , Yichen Wang , Yifang Dang , Fang Li , Jingna Feng , Evan Yu , Cui Tao

Deep neural networks (DNNs) are increasingly being deployed in high-stakes applications, from self-driving cars to biometric authentication. However, their unpredictable and unreliable behaviors in real-world settings require new approaches…

密码学与安全 · 计算机科学 2025-10-01 Firas Ben Hmida , Abderrahmen Amich , Ata Kaboudi , Birhanu Eshete

Social influence prediction has permeated many domains, including marketing, behavior prediction, recommendation systems, and more. However, traditional methods of predicting social influence not only require domain expertise,they also rely…

社会与信息网络 · 计算机科学 2022-07-27 Yufei Liu , Jie Cao , Dechang Pi

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

动力系统 · 数学 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

When designing control strategies for an infectious disease it is critical to identify the key pathways of transmission. Data on infected hosts - when they were born, where they lived and with whom they interacted - can help infer sources…

定量方法 · 定量生物学 2026-03-27 Anthony J Wood , Aeron R Sanchez , Rowland R Kao

In this work, we provide a new formulation for Graph Convolutional Neural Networks (GCNNs) for link prediction on graph data that addresses common challenges for biomedical knowledge graphs (KGs). We introduce a regularized attention…

机器学习 · 计算机科学 2018-12-04 Daniel Neil , Joss Briody , Alix Lacoste , Aaron Sim , Paidi Creed , Amir Saffari

In the research, we developed a computer vision solution to support diagnostic radiology in differentiating between COVID-19 pneumonia, influenza virus pneumonia, and normal biomarkers. The chest radiograph appearance of COVID-19 pneumonia…

图像与视频处理 · 电气工程与系统科学 2021-12-15 Julianna Antonchuk , Benjamin Prescott , Philip Melanchthon , Robin Singh

Under the epidemic of the novel coronavirus disease 2019 (COVID-19), chest X-ray computed tomography imaging is being used for effectively screening COVID-19 patients. The development of computer-aided systems based on deep neural networks…

计算机视觉与模式识别 · 计算机科学 2020-12-21 Hokuto Hirano , Kazuki Koga , Kazuhiro Takemoto

Graph neural networks (GNNs) appear to be powerful tools to learn state representations for agents in distributed, decentralized multi-agent systems, but generate catastrophically incorrect predictions when nodes update asynchronously…

机器学习 · 计算机科学 2025-07-23 Olga Solodova , Nick Richardson , Deniz Oktay , Ryan P. Adams

Protein-ligand interactions (PLIs) are fundamental to biochemical research and their identification is crucial for estimating biophysical and biochemical properties for rational therapeutic design. Currently, experimental characterization…

机器学习 · 统计学 2021-12-01 Carter Knutson , Mridula Bontha , Jenna A. Bilbrey , Neeraj Kumar