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相关论文: Multiscale Model of Clogging in Microfluidic Devic…

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We study a reaction-diffusion model posed on two distinct spatial scales that accounts for diffusion, aggregation, fragmentation, and deposition of populations of colloidal particles within a porous material. In this model, the macroscopic…

偏微分方程分析 · 数学 2026-04-14 Christos Nikolopoulos , Michael Eden , Adrian Muntean

Stochastic models for pore collapse in granular materials are developed. First, a general fluctuating stress-strain relation for a plastic flow rule is derived. The fluctuations account for non-associativity in plastic deformations…

软凝聚态物质 · 物理学 2020-03-02 Joseph Bakarji , Daniel M. Tartakovsky

The objective of this work is to assess computationally efficient coarse-grained plasticity models against high-fidelity crystal plasticity simulations for magnesium polycrystals over a wide range of textures and grain sizes. A basic…

材料科学 · 物理学 2026-01-13 R. Vigneshwaran , Showren Datta , A. A. Benzerga , Shailendra P. Joshi

Clogging can occur whenever a suspension of particles flows through a confined system. The formation of clogs is often correlated to a reduction in the cross-section of the channel. In this study, we consider the clogging by bridging, i.e.,…

软凝聚态物质 · 物理学 2022-08-25 Nathan Vani , Sacha Escudier , Alban Sauret

A recent theory for stress transmission in isostatic granular and cellular systems predicts a constitutive equation that couples the stress field to the local microstructure. The theory could not be applied to macroscopic systems because…

软凝聚态物质 · 物理学 2009-11-10 Raphael Blumenfeld

We present simulations of granular flows in a modified Couette cell, using a continuum model recently proposed for dense granular flows. Based on a friction coefficient, which depends on an inertial number, the model captures the positions…

软凝聚态物质 · 物理学 2009-11-13 Pierre Jop

We review a few representative examples of granular experiments or models where phase separation, accompanied by domain coarsening, is a relevant phenomenon. We first elucidate the intrinsic non-equilibrium, or athermal, nature of granular…

统计力学 · 物理学 2015-04-29 Andrea Baldassarri , Andrea Puglisi , Alessandro Sarracino

Bioclogging, the clogging of pores with living particles, is a complex process that involves various coupled mechanisms such as hydrodynamics and particle properties. This article explores bioclogging at the microscale level. At this scale,…

The deformation and flow of disordered solids, such as metallic glasses and concentrated emulsions, involves swift localized rearrangements of particles that induce a long-range deformation field. To describe these heterogeneous processes,…

无序系统与神经网络 · 物理学 2019-01-02 Alexandre Nicolas , Ezequiel E. Ferrero , Kirsten Martens , Jean-Louis Barrat

The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and…

细胞行为 · 定量生物学 2016-01-11 Mohammad Aghaamoo , Zhifeng Zhang , Xiaolin Chen , Jie Xu

Soft colloids are increasingly used as model systems to address fundamental issues such as crystallisation and the glass and jamming transitions. Among the available classes of soft colloids, microgels are emerging as the gold standard.…

Thin films made of deformable micro- and nano-units, such as biological membranes, polymer interfaces, and particle-laden liquid surfaces, exhibit a complex behavior during drying, with consequences for various applications like wound…

The first paper of this series [J. Chem. Phys. 158, 034103 (2023)] demonstrated that excess entropy scaling holds for both fine-grained and corresponding coarse-grained (CG) systems. Despite its universality, a more exact determination of…

化学物理 · 物理学 2023-01-18 Jaehyeok Jin , Kenneth S. Schweizer , Gregory A. Voth

We describe an approach for modeling fluid concentration profiles in grid-based microfluidic chips for fluid mixing. This approach provides an algorithm that predicts fluid concentrations at the chip outlets. Our algorithm significantly…

计算工程、金融与科学 · 计算机科学 2019-11-19 Huong Luu , Marek Chrobak

Clogging of microchannels due to particle adhesion on the walls is a serious problem in many industrial processes. As such, the service life of microfluidic systems is determined by their ability to maintain flow without interruption over a…

流体动力学 · 物理学 2023-12-12 Lyudmila S. Klimenko , Boris S. Maryshev

Single cell and regularly cells docking inside the microstructure of microfluidic systems are advantageous in different analyses of single cells exposed to equal drug concentration and mechanical stimulus. In this study, we investigated…

生物物理 · 物理学 2020-08-05 Sina Ahandoust , Maryam Saadatmand

We report on experiments that consist in deforming a collection of monodisperse droplets produced by a microfluidic chip through a flow-focusing device. We show that a proper numerical modelling of the flow is necessary to access the stress…

软凝聚态物质 · 物理学 2018-05-23 Corentin Trégouët , Thomas Salez , Cécile Monteux , Mathilde Reyssat

This study investigates the coupled deformation and flow behavior of thin, hyper-elastic, porous membranes subjected to pressure loading. Using bulge test experiments, optical deformation measurements, and flow rate characterization, we…

流体动力学 · 物理学 2026-01-19 Alexander Gehrke , Zoe King , Kenneth S. Breuer

We present a single, unified, multi-scale model to study the attachment\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The…

细胞行为 · 定量生物学 2015-04-23 Sarthok Sircar , Anthony J. Roberts

Complex systems, in many different scientific sectors, show coarse-grain properties with simple growth laws with respect to fundamental microscopic algorithms. We propose a classification scheme of growth laws which includes human aging,…

生物物理 · 物理学 2012-07-17 P. Castorina , P. Blanchard