相关论文: TargetNet: Functional microRNA Target Prediction w…

MicroRNAs (miRNAs) are short sequences of ribonucleic acids that control the expression of target messenger RNAs (mRNAs) by binding them. Robust prediction of miRNA-mRNA pairs is of utmost importance in deciphering gene regulations but has…

MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression at the post-transcriptional level through complementary base pairing with the target mRNA, leading to mRNA degradation and blocking translation process. Any…

Since microRNAs (miRNAs) play a crucial role in post-transcriptional gene regulation, miRNA identification is one of the most essential problems in computational biology. miRNAs are usually short in length ranging between 20 and 23 base…

MicroRNAs (miRNAs) are a class of small noncoding RNAs that can regulate many genes by base pairing to sites in mRNAs. The functionality of miRNAs overlaps that of short interfering RNAs (siRNAs), and many features of miRNA targeting have…

MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play an important role in post-transcriptional gene regulation. However, the experimental determination of miRNA sequence and structure is both expensive and time-consuming.…

MicroRNA (miRNA) are small non-coding RNAs that regulates the gene expression at the post-transcriptional level. Determining whether a sequence segment is miRNA is experimentally challenging. Also, experimental results are sensitive to the…

Multi-target tracking (MTT) is a classical signal processing task, where the goal is to estimate the states of an unknown number of moving targets from noisy sensor measurements. In this paper, we revisit MTT from a deep learning…

It has been estimated that about 30% of the genes in the human genome are regulated by microRNAs (miRNAs). These are short RNA sequences that can down-regulate the levels of mRNAs or proteins in animals and plants. Genes regulated by miRNAs…

Click-through rate (CTR) prediction tasks play a pivotal role in real-world applications, particularly in recommendation systems and online advertising. A significant research branch in this domain focuses on user behavior modeling. Current…

Activity cliff prediction is a critical task in drug discovery and material design. Existing computational methods are limited to handling single binding targets, which restricts the applicability of these prediction models. In this paper,…

Click-Through Rate (CTR) prediction is a core task in nowadays commercial recommender systems. Feature crossing, as the mainline of research on CTR prediction, has shown a promising way to enhance predictive performance. Even though various…

Most uses of machine learning today involve training a model from scratch for a particular task, or sometimes starting with a model pretrained on a related task and then fine-tuning on a downstream task. Both approaches offer limited…

MicroRNAs (miRs) are robust regulators of gene expression, implicated in most biological processes. microRNAs predominantly downregulate the expression of genes post-transcriptionally and each miR is predicted to target several hundred…

We developed an online database, ExprTargetDB, of human miRNA targets predicted by an approach that integrates gene expression profiling into a broader framework involving important features of miRNA target site predictions.

Advertising and feed ranking are essential to many Internet companies such as Facebook. Among many real-world advertising and feed ranking systems, click through rate (CTR) prediction plays a central role. In recent years, many neural…

Over the past few years, microRNAs (miRNAs) have emerged as a new prominent class of gene regulatory factors that negatively regulate expression of approximately one-third of the genes in animal genomes at post-transcriptional level.…

Click-through rate (CTR) estimation is a fundamental task in personalized advertising and recommender systems and it's important for ranking models to effectively capture complex high-order features.Inspired by the success of ELMO and Bert…

The CTR (Click-Through Rate) prediction plays a central role in the domain of computational advertising and recommender systems. There exists several kinds of methods proposed in this field, such as Logistic Regression (LR), Factorization…

Almost all the state-of-the-art neural networks for computer vision tasks are trained by (1) pre-training on a large-scale dataset and (2) finetuning on the target dataset. This strategy helps reduce dependence on the target dataset and…

The Human Genome Project has led to an exponential increase in data related to the sequence, structure, and function of biomolecules. Bioinformatics is an interdisciplinary research field that primarily uses computational methods to analyze…