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This work proposes a framework for multistage adjustable robust optimization that unifies the treatment of three different types of endogenous uncertainty, where decisions, respectively, (i) alter the uncertainty set, (ii) affect the…

最优化与控制 · 数学 2020-08-31 Qi Zhang , Wei Feng

Stochastic process discovery is concerned with deriving a model capable of reproducing the stochastic character of observed executions of a given process, stored in a log. This leads to an optimisation problem in which the model's parameter…

形式语言与自动机理论 · 计算机科学 2025-05-01 Pierre Cry , Paolo Ballarini , András Horváth , Pascale Le Gall

We present an online stochastic model predictive control framework for demand charge management for a grid-connected consumer with attached electrical energy storage. The consumer we consider must satisfy an inflexible but stochastic…

系统与控制 · 电气工程与系统科学 2020-07-07 Benjamin Flamm , Guillermo Ramos , Annika Eichler , John Lygeros

Production planning must account for uncertainty in a production system, arising from fluctuating demand forecasts. Therefore, this article focuses on the integration of updated customer demand into the rolling horizon planning cycle. We…

计量经济学 · 经济学 2024-09-27 Manuel Schlenkrich , Wolfgang Seiringer , Klaus Altendorfer , Sophie N. Parragh

Plant biomass estimation is critical due to the variability of different environmental factors and crop management practices associated with it. The assessment is largely impacted by the accurate prediction of different environmental…

人工智能 · 计算机科学 2023-02-07 Syeda Nyma Ferdous , Xin Li , Kamalakanta Sahoo , Richard Bergman

The reduction of the computational effort is desirable for the simulation of marine ecosystem models. Using a marine ecosystem model, the assessment and the validation of annual periodic solutions (i.e., steady annual cycles) against…

种群与进化 · 定量生物学 2022-07-29 Markus Pfeil , Thomas Slawig

Any organism is embedded in an environment that changes over time. The timescale for and statistics of environmental change, the precision with which the organism can detect its environment, and the costs and benefits of particular protein…

定量方法 · 定量生物学 2023-07-19 David A. Sivak , Matt Thomson

Chemotherapy appointment scheduling is a challenging problem due to the uncertainty in pre-medication and infusion durations. In this paper, we formulate a two-stage stochastic mixed integer programming model for the chemotherapy…

最优化与控制 · 数学 2021-01-20 Nur Banu Demir , Serhat Gul , Melih Celik

Organisms adapt to volatile environments by integrating sensory information with internal memory, yet their information processing is constrained by resource limitations. Such limitations can fundamentally alter optimal estimation…

生物物理 · 物理学 2025-11-14 Takehiro Tottori , Tetsuya J. Kobayashi

In this study, we introduce a sensitivity analysis methodology for stochastic systems in chemistry, where dynamics are often governed by random processes. Our approach is based on gradient estimation via finite differences, averaging…

定量方法 · 定量生物学 2026-01-12 Erika M. Herrera Machado , Jakob L. Andersen , Rolf Fagerberg , Daniel Merkle

Temporal point processes have been widely applied to model event sequence data generated by online users. In this paper, we consider the problem of how to design the optimal control policy for point processes, such that the stochastic…

机器学习 · 计算机科学 2017-11-13 Yichen Wang , Grady Williams , Evangelos Theodorou , Le Song

Living systems often function with regulatory interactions, but the question of how activity, stochasticity and regulations work together for achieving different goals still remains puzzling. We propose a stochastic model of an active…

软凝聚态物质 · 物理学 2026-03-02 Tai Han , Fanlong Meng

A goal of systems biology is to understand the dynamics of intracellular systems. Stochastic chemical kinetic models are often utilized to accurately capture the stochastic nature of these systems due to low numbers of molecules. Collecting…

统计计算 · 统计学 2015-03-17 Jarad Niemi , Matthew Wheeler

Dynamical systems modeling, particularly via systems of ordinary differential equations, has been used to effectively capture the temporal behavior of different biochemical components in signal transduction networks. Despite the recent…

定量方法 · 定量生物学 2023-01-06 Nathaniel J. Linden , Boris Kramer , Padmini Rangamani

We derived a number of numerical methods to treat biomolecular systems with multiple time scales. Based on the splitting of the operators associated with the slow-varying and fast-varying forces, new multiple time-stepping (MTS) methods are…

数值分析 · 数学 2015-01-15 Chao Liang , Xiaolan Yuan , Xiantao Li

With the rapid growth of artificial intelligence (AI) and cloud services, data centers have become critical infrastructures driving digital economies, with increasing energy demand heightening concerns over electricity use and carbon…

系统与控制 · 电气工程与系统科学 2025-10-30 Zhentong Shao , Nanpeng Yu , Daniel Wong

In multistage decision problems, it is often the case that an initial strategic decision (such as investment) is followed by many operational ones (operating the investment). Such initial strategic decision can be seen as a parameter…

最优化与控制 · 数学 2026-03-17 Adrien Le Franc , Pierre Carpentier , Jean-Philippe Chancelier , Michel de Lara

This study presents a comprehensive approach to optimizing inventory management under stochastic demand by leveraging Monte Carlo Simulation (MCS) with grid search and Bayesian optimization. By using a business case of historical demand…

最优化与控制 · 数学 2024-07-01 Sarit Maitra

Wind farms can increase annual energy production (AEP) with advanced control algorithms by coordinating the set points of individual turbine controllers across the farm. However, it remains a significant challenge to achieve performance…

最优化与控制 · 数学 2020-03-18 Yi Guo , Mario Rotea , Tyler Summers

Software-intensive systems constantly evolve. To prevent software changes from unintentionally introducing costly system defects, it is important to understand their impact to reduce risk. However, it is in practice nearly impossible to…

软件工程 · 计算机科学 2022-05-18 Dennis Hendriks , Arjan van der Meer , Wytse Oortwijn