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The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Accurate and fast assessment of resection margins is an essential part of a dermatopathologist's clinical routine. In this work, we successfully develop a deep learning method to assist the pathologists by marking critical regions that have…

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Whole Slide Imaging (WSI) has become an important topic during the last decade. Even though significant progress in both medical image processing and computational resources has been achieved, there are still problems in WSI that need to be…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Wafa Chenni , Habib Herbi , Morteza Babaie , H. R. Tizhoosh

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

计算机视觉与模式识别 · 计算机科学 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Rune Wetteland , Kjersti Engan , Trygve Eftestøl , Vebjørn Kvikstad , Emilius A. M. Janssen

Whole slide image (WSI) analysis has become increasingly important in the medical imaging community, enabling automated and objective diagnosis, prognosis, and therapeutic-response prediction. However, in clinical practice, the…

计算机视觉与模式识别 · 计算机科学 2023-08-28 Yanyan Huang , Weiqin Zhao , Shujun Wang , Yu Fu , Yuming Jiang , Lequan Yu

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Recent advancements in whole slide imaging (WSI) have moved pathology closer to digital practice. Existing systems require precise mechanical control and the cost is prohibitive for most individual pathologists. Here we report a low-cost…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Chengfei Guo , Zichao Bian , Shaowei Jiang , Michael Murphy , Jiakai Zhu , Ruihai Wang , Pengming Song , Xiaopeng Shao , Yongbing Zhang , Guoan Zheng

Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…

定量方法 · 定量生物学 2026-04-13 Muhammad Haseeb Ahmad , Sharmila Rajendran , Damion Young , Jon Mason

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Nucleus detection in histopathology whole slide images (WSIs) is crucial for a broad spectrum of clinical applications. The gigapixel size of WSIs necessitates the use of sliding window methodology for nucleus detection. However, mainstream…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Zhongyi Shui , Honglin Li , Yunlong Zhang , Yuxuan Sun , Yiwen Ye , Pingyi Chen , Ruizhe Guo , Lei Cui , Chenglu Zhu , Lin Yang

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Feng Gu , Nikolay Burlutskiy , Mats Andersson , Lena Kajland Wilen

Digital pathology is revolutionizing the field of pathology by enabling the digitization, storage, and analysis of tissue samples as whole slide images (WSIs). WSIs are gigapixel files that capture the intricate details of tissue samples,…

图像与视频处理 · 电气工程与系统科学 2024-09-10 S. Hemati , Krishna R. Kalari , H. R. Tizhoosh

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

图像与视频处理 · 电气工程与系统科学 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

计算机视觉与模式识别 · 计算机科学 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

图像与视频处理 · 电气工程与系统科学 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova