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Researchers are often interested in estimating effects of generalized time-varying treatment strategies on the mean of an outcome at one or more selected follow-up times of interest. For example, the Medications and Weight Gain in PCORnet…

Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation…

统计方法学 · 统计学 2024-08-19 Yihan Bao , Lauren Bell , Elizabeth Williamson , Claire Garnett , Tianchen Qian

In test equating, ensuring score comparability across different test forms is crucial but particularly challenging when test groups are non-equivalent and no anchor test is available. Local test equating aims to satisfy Lord's equity…

统计方法学 · 统计学 2026-04-10 Gabriel Wallin , Marie Wiberg

Mendelian randomization uses genetic variants as instrumental variables to make causal inferences about the effects of modifiable risk factors on diseases from observational data. One of the major challenges in Mendelian randomization is…

统计方法学 · 统计学 2024-10-29 Youpeng Su , Siqi Xu , Yilei Ma , Ping Yin , Wing Kam Fung , Hongwei Jiang , Peng Wang

Mendelian randomization (MR) has become a popular approach to study the effect of a modifiable exposure on an outcome by using genetic variants as instrumental variables. A challenge in MR is that each genetic variant explains a relatively…

统计方法学 · 统计学 2020-10-13 Ting Ye , Jun Shao , Hyunseung Kang

Marginal structural models (MSMs) with inverse probability weighting offer an approach to estimating causal effects of treatment sequences on repeated outcome measures in the presence of time-varying confounding and dependent censoring.…

统计方法学 · 统计学 2018-07-02 Sean Yiu , Li Su

Inverse weighting with an estimated propensity score is widely used by estimation methods in causal inference to adjust for confounding bias. However, directly inverting propensity score estimates can lead to instability, bias, and…

统计方法学 · 统计学 2025-04-11 Lars van der Laan , Ziming Lin , Marco Carone , Alex Luedtke

Propensity score methods are increasingly being used to reduce estimation bias of treatment effects for observational studies. Previous research has shown that propensity score methods consistently estimate the marginal hazard ratio for…

统计方法学 · 统计学 2019-11-19 Haodi Liang , Cecilia Cotton

Combining information from multiple samples is often needed in biomedical and economic studies, but the differences between these samples must be appropriately taken into account in the analysis of the combined data. We study estimation for…

统计方法学 · 统计学 2018-08-14 Heng Shu , Zhiqiang Tan

We study off-policy evaluation in the setting of contextual bandits, where we aim to evaluate a new policy using historical data that consists of contexts, actions and received rewards. This historical data typically does not faithfully…

机器学习 · 计算机科学 2026-03-11 Rong J. B. Zhu

This paper develops methods for estimating the natural direct and indirect effects in causal mediation analysis. The efficient influence function-based estimator (EIF-based estimator) and the inverse probability weighting estimator (IPW…

统计方法学 · 统计学 2025-12-11 Kentaro Kawato

Causal inference requires evaluating models on balanced distributions between treatment and control groups, while training data often exhibits imbalance due to historical decision-making policies. Most conventional statistical methods…

机器学习 · 统计学 2025-11-21 Akira Tanimoto

Sequential estimation of the success probability $p$ in inverse binomial sampling is considered in this paper. For any estimator $\hat p$, its quality is measured by the risk associated with normalized loss functions of linear-linear or…

统计理论 · 数学 2018-12-18 Luis Mendo

The inverse probability (IPW) and doubly robust (DR) estimators are often used to estimate the average causal effect (ATE), but are vulnerable to outliers. The IPW/DR median can be used for outlier-resistant estimation of the ATE, but the…

统计方法学 · 统计学 2024-09-16 Kazuharu Harada , Hironori Fujisawa

In a widely cited paper, Xie and Liu (henceforth XL) proposed to use inverse probability of treatment weighting (IPTW) to account for possible confounding in observational studies with survival endpoints subject to right censoring. Their…

统计方法学 · 统计学 2025-11-04 Zhiwei Zhang , Yongwu Shao , Zhishen Ye

We consider estimation of average treatment effects given observational data with high-dimensional pretreatment variables. Existing methods for this problem typically assume some form of sparsity for the regression functions. In this work,…

统计方法学 · 统计学 2024-04-12 Yuhao Wang , Rajen D. Shah

Observational data have been actively used to estimate treatment effect, driven by the growing availability of electronic health records (EHRs). However, EHRs typically consist of longitudinal records, often introducing time-dependent…

机器学习 · 计算机科学 2024-06-14 Junghwan Lee , Simin Ma , Nicoleta Serban , Shihao Yang

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration…

统计方法学 · 统计学 2026-03-31 Mst Moushumi Pervin , Hengfang Wang , Jae Kwang Kim

A key methodological challenge in observational studies with interference between units is twofold: (1) each unit's outcome may depend on many others' treatments, and (2) treatment assignments may exhibit complex dependencies across units.…

统计方法学 · 统计学 2025-12-17 Souhardya Sengupta , Kosuke Imai , Georgia Papadogeorgou

RCTs sometimes test interventions that aim to improve existing services targeted to a subset of individuals identified after randomization. Accordingly, the treatment could affect the composition of service recipients and the offered…

统计方法学 · 统计学 2022-05-18 Peter Z. Schochet