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Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Neuroblastoma (NB), a leading cause of childhood cancer mortality, exhibits significant histopathological variability, necessitating precise subtyping for accurate prognosis and treatment. Traditional diagnostic methods rely on subjective…

计算机视觉与模式识别 · 计算机科学 2025-03-20 Huangwei Chen , Yifei Chen , Zhenyu Yan , Mingyang Ding , Chenlei Li , Zhu Zhu , Feiwei Qin

We study multimodal survival analysis integrating clinical text, tabular covariates, and genomic profiles using locally deployable large language models (LLMs). As many institutions face tight computational and privacy constraints, this…

机器学习 · 计算机科学 2026-03-24 Moritz Gögl , Christopher Yau

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

计算机视觉与模式识别 · 计算机科学 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

计算机视觉与模式识别 · 计算机科学 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

Cancer is the uncontrollable cell division of abnormal cells inside the human body, which can spread to other body organs. It is one of the non-communicable diseases (NCDs) and NCDs accounts for 71% of total deaths worldwide whereas lung…

图像与视频处理 · 电气工程与系统科学 2021-12-28 Neha Baranwal , Preethi Doravari , Renu Kachhoria

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

计算机视觉与模式识别 · 计算机科学 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography…

计算机视觉与模式识别 · 计算机科学 2025-04-10 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza

Nasopharyngeal Carcinoma (NPC) is a malignant epithelial cancer arising from the nasopharynx. Survival prediction is a major concern for NPC patients, as it provides early prognostic information to plan treatments. Recently, deep survival…

图像与视频处理 · 电气工程与系统科学 2022-09-20 Mingyuan Meng , Bingxin Gu , Lei Bi , Shaoli Song , David Dagan Feng , Jinman Kim

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

Several deep learning algorithms have been developed to predict survival of cancer patients using whole slide images (WSIs).However, identification of image phenotypes within the WSIs that are relevant to patient survival and disease…

图像与视频处理 · 电气工程与系统科学 2022-11-30 Xingyu Li , Jitendra Jonnagaddala , Min Cen , Hong Zhang , Xu Steven Xu

As advancements in technology and medicine are being made, many countries are still unable to access quality medical care due to cost and lack of qualified medical personnel. This discrepancy in healthcare has caused many preventable…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Kyler Larsen

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

机器学习 · 计算机科学 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

声音 · 计算机科学 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Cardiovascular disease (CVD) is a leading cause of death in the lung cancer screening population. Chest CT scans made in lung cancer screening are suitable for identification of participants at risk of CVD. Existing methods analyzing CT…

计算机视觉与模式识别 · 计算机科学 2018-10-05 Sanne G. M. van Velzen , Majd Zreik , Nikolas Lessmann , Max A. Viergever , Pim A. de Jong , Helena M. Verkooijen , Ivana Išgum

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

定量方法 · 定量生物学 2016-11-29 He Yang , Hengyong Yu , Ge Wang