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We propose a discrete transition-based reweighting analysis method (dTRAM) for analyzing configuration-space-discretized simulation trajectories produced at different thermodynamic states (temperatures, Hamiltonians, etc.) dTRAM provides…

数据分析、统计与概率 · 物理学 2015-06-23 Hao Wu , Antonia S. J. S. Mey , Edina Rosta , Frank Noé

One of the key limitations of Molecular Dynamics simulations is the computational intractability of sampling protein conformational landscapes associated with either large system size or long timescales. To overcome this bottleneck, we…

生物大分子 · 定量生物学 2018-07-09 Zahra Shamsi , Kevin J. Cheng , Diwakar Shukla

Wireless sensor networks are often designed to perform two tasks: sensing a physical field and transmitting the data to end-users. A crucial aspect of the design of a WSN is the minimization of the overall energy consumption. Previous…

信息论 · 计算机科学 2014-01-07 Zichong Chen , Juri Ranieri , Runwei Zhang , Martin Vetterli

Diffusion models have been successful on a range of conditional generation tasks including molecular design and text-to-image generation. However, these achievements have primarily depended on task-specific conditional training or…

机器学习 · 统计学 2024-11-26 Luhuan Wu , Brian L. Trippe , Christian A. Naesseth , David M. Blei , John P. Cunningham

We report a systematic and accurate approach for deriving the bulk free energy surface (FES), a function of temperature, polarization, and strain, from the first-principles density functional theory (DFT) of proper ferroelectrics. The core…

材料科学 · 物理学 2026-02-10 Pinchen Xie , Yixiao Chen , Xinyu Xu , Zhi Yao , Weinan E , Roberto Car

Ensuring a satisfactory statistical convergence of anharmonic thermodynamic properties requires sampling of many atomic configurations, however the methods to obtain those necessarily produce correlated samples, thereby reducing the…

统计力学 · 物理学 2022-06-07 Erki Metsanurk

Calculating transition probabilities between different states of multistable climate tipping systems is computationally challenging in high-dimensional models. Targeted algorithms, such as the Trajectory-Adaptive Multilevel Splitting (TAMS)…

大气与海洋物理 · 物理学 2026-03-24 Lucas Esclapez , Valérian Jacques-Dumas , Reyk Börner , Laurent Soucasse , Henk A. Dijkstra

Temporal Action Segmentation (TAS) is an essential task in video analysis, aiming to segment and classify continuous frames into distinct action segments. However, the ambiguous boundaries between actions pose a significant challenge for…

计算机视觉与模式识别 · 计算机科学 2024-08-06 Shuaibing Wang , Shunli Wang , Mingcheng Li , Dingkang Yang , Haopeng Kuang , Ziyun Qian , Lihua Zhang

We presented an efficient algorithm, fast adaptive flat-histogram ensemble (FAFE), to estimate the density of states (DOS) and to enhance sampling in large systems. FAFE calculates the means of an arbitrary extensive variable $U$ in…

统计力学 · 物理学 2008-11-13 Xin Zhou , Yi Jiang

We address the issue of the exploding computational requirements of recent State-of-the-art (SOTA) open set multimodel 3D mapping (dense 3D mapping) algorithms and present Voxel-Aggregated Feature Synthesis (VAFS), a novel approach to dense…

计算机视觉与模式识别 · 计算机科学 2025-01-10 Owen Burns , Rizwan Qureshi

Sampling from constrained distributions has a wide range of applications, including in Bayesian optimization and robotics. Prior work establishes convergence and feasibility guarantees for constrained sampling, but assumes that the feasible…

机器学习 · 计算机科学 2026-05-13 Cornelius V. Braun , Tilman Burghoff , Marc Toussaint

We show how thermodynamic properties of molecular models can be computed over a large, multidimensional parameter space by combining multistate reweighting analysis with a linear basis function approach. This approach reduces the…

化学物理 · 物理学 2016-05-18 Levi N. Naden , Michael R. Shirts

Recently, nanofluidics experiments have been used to characterize the behavior of single DNA molecules confined to narrow slits etched with arrays of nanopits. Analysis of the experimental data relies on analytical estimates of the…

软凝聚态物质 · 物理学 2024-09-09 James M. Polson , Matthew Kozma

The sliced Wasserstein (SW) distance has been widely recognized as a statistically effective and computationally efficient metric between two probability measures. A key component of the SW distance is the slicing distribution. There are…

机器学习 · 统计学 2024-01-02 Khai Nguyen , Nhat Ho

Importance Sampling methods are broadly used to approximate posterior distributions or some of their moments. In its standard approach, samples are drawn from a single proposal distribution and weighted properly. However, since the…

统计计算 · 统计学 2019-11-05 Víctor Elvira , Luca Martino , David Luengo , Mónica F. Bugallo

Recent Lyman-$\alpha$ forest tomography measurements of the intergalactic medium (IGM) have revealed a wealth of cosmic structures at high redshift ($z\sim 2.5$). In this work, we present the Tomographic Absorption Reconstruction and…

宇宙学与河外天体物理 · 物理学 2020-05-18 Benjamin Horowitz , Khee-Gan Lee , Martin White , Alex Krolewski , Metin Ata

Data assimilation (DA) estimates the state of an evolving dynamical system from noisy, partial observations, and is widely used in scientific simulation as well as weather and climate science. In practice, filtering methods rely on…

图像与视频处理 · 电气工程与系统科学 2026-05-15 Yixuan Jia , Siyi Chen , Yida Pan , Xiao Li , Lianghe Shi , Chanyong Jung , Haijie Yuan , Ismail Alkhouri , Yue Cynthia Wu , Saiprasad Ravishankar , Jeffrey A Fessler , Qing Qu

We extend the weighted ensemble (WE) path sampling method to perform rigorous statistical sampling for systems at steady state. The straightforward steady-state implementation of WE is directly practical for simple landscapes, but not when…

生物物理 · 物理学 2015-05-14 Divesh Bhatt , Bin W. Zhang , Daniel M. Zuckerman

Sparsely annotated semantic segmentation (SASS) aims to train a segmentation network with coarse-grained (i.e., point-, scribble-, and block-wise) supervisions, where only a small proportion of pixels are labeled in each image. In this…

计算机视觉与模式识别 · 计算机科学 2022-03-23 Zhiyuan Liang , Tiancai Wang , Xiangyu Zhang , Jian Sun , Jianbing Shen

In this paper we introduce Farthest Sampling Segmentation (FSS), a new method for segmentation of triangulated surfaces, which consists of two fundamental steps: the computation of a submatrix $W^k$ of the affinity matrix $W$ and the…