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Coronavirus disease 2019 (COVID-19) has created an unprecedented need for breathing assistance devices. Since the demand for commercial, full-featured ventilators is far higher than the supply capacity, many rapid-response ventilators are…

Background: At the beginning of 2020, a high number of COVID-19 cases affected Italy in a short period, causing a difficult supply of medical equipment. To deal with the problem, many healthcare operators readapted different masks to…

HEV is a low-cost, versatile, high-quality ventilator, which has been designed in response to the COVID-19 pandemic. The ventilator is intended to be used both in and out of hospital intensive care units, and for both invasive and…

Cardiac arrest is very common nowadays. Sudden heart attack is a condition where the heart suddenly stops beating causing a significant decrease in blood flow to the brain. The first step in medical point of view is for a patient…

We present a viable prototype of a simple mechanical ventilator intended as a last resort to ventilate COVID-19 patients. The prototype implements the pressure-controlled continuous mandatory ventilation mode (PC-CMV) with settable…

During the beginning of 2020, the Covid-19 pandemic took the world by surprise, rapidly spreading undetected between and within many countries and wreaking havoc on the global economy both through death tolls and lockdowns. Healthcare…

Patients suffering from obstructive sleep apnea are mainly treated with continuous positive airway pressure (CPAP). Good compliance with this therapy is broadly accepted as more than 4h of CPAP average use nightly. Although it is a highly…

Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to…

We propose the design of a ventilator which can be easily manufactured and integrated into the hospital environment to support COVID-19 patients. The unit is designed to support standard ventilator modes of operation, most importantly PRVC…

Heart failure (HF) is one of the most prevalent life-threatening cardiovascular diseases in which 6.5 million people are suffering in the USA and more than 23 million worldwide. Mechanical circulatory support of HF patients can be achieved…

Following up a recent study describing a flexible plasma source operated in planar geometry, the performance of a cold atmospheric plasma jet (CAPJ) matrix emanating radially from a soft cylindrical surface in the open air is presented. The…

Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…

Non-thermal atmospheric pressure plasma jets (APPJs) are increasingly used in biomedical applications due to their low temperatures and ability to generate reactive oxygen and nitrogen species (RONS), making them suitable for sensitive…

We propose a data-driven approach for deep convolutional neural network compression that achieves high accuracy with high throughput and low memory requirements. Current network compression methods either find a low-rank factorization of…

Fontan operation as the current standard of care for the palliation of single ventricle defects results in significant late complications. Using a mechanical circulatory device for the right circulation to serve the function of the missing…

In this research, we presented the method of inhalation therapy with noble gas micro-doses and results of clinical studies in hospital of Russian Academy of Sciences (RAS). We have designed a device that allows dosed injection of noble gas…

Accurately and precisely characterizing the morphology of small pulmonary structures from Computed Tomography (CT) images, such as airways and vessels, is becoming of great importance for diagnosis of pulmonary diseases. The smaller…

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

Plasma sources suitable to generate low temperature plasmas has been fundamental for the advances in plasma medicine. In this research field, plasma sources must comply with stringent conditions for clinical applications. The main…

Cold atmospheric pressure plasmas are crucial for applications in medicine, agriculture, and material processing, where their interaction with ambient air generates reactive oxygen and nitrogen species for disinfection and treatment…