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Classification and differentiation of small pathological objects may greatly vary among human raters due to differences in training, expertise and their consistency over time. In a radiological setting, objects commonly have high…

Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image…

计算机视觉与模式识别 · 计算机科学 2018-06-08 Alain Jungo , Raphael Meier , Ekin Ermis , Marcela Blatti-Moreno , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

The problem of inter-rater variability is often discussed in the context of manual labeling of medical images. The emergence of data-driven approaches such as Deep Neural Networks (DNNs) brought this issue of raters' disagreement to the…

图像与视频处理 · 电气工程与系统科学 2020-06-02 Or Shwartzman , Harel Gazit , Ilan Shelef , Tammy Riklin-Raviv

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

图像与视频处理 · 电气工程与系统科学 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Medical tasks are prone to inter-rater variability due to multiple factors such as image quality, professional experience and training, or guideline clarity. Training deep learning networks with annotations from multiple raters is a common…

图像与视频处理 · 电气工程与系统科学 2023-01-13 Andreanne Lemay , Charley Gros , Enamundram Naga Karthik , Julien Cohen-Adad

Recent developments in deep learning (DL) techniques have led to great performance improvement in medical image segmentation tasks, especially with the latest Transformer model and its variants. While labels from fusing multi-rater manual…

图像与视频处理 · 电气工程与系统科学 2023-08-15 Parinaz Roshanzamir , Hassan Rivaz , Joshua Ahn , Hamza Mirza , Neda Naghdi , Meagan Anstruther , Michele C. Battié , Maryse Fortin , Yiming Xiao

Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

计算机视觉与模式识别 · 计算机科学 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

Measuring uncertainties in the output of a deep learning method is useful in several ways, such as in assisting with interpretation of the outputs, helping build confidence with end users, and for improving the training and performance of…

机器学习 · 计算机科学 2022-09-20 Luke Whitbread , Mark Jenkinson

Despite the recent improvements in overall accuracy, deep learning systems still exhibit low levels of robustness. Detecting possible failures is critical for a successful clinical integration of these systems, where each data point…

图像与视频处理 · 电气工程与系统科学 2019-10-14 Alain Jungo , Mauricio Reyes

Medical images are generally labeled by multiple experts before the final ground-truth labels are determined. Consensus or disagreement among experts regarding individual images reflects the gradeability and difficulty levels of the image.…

计算机视觉与模式识别 · 计算机科学 2020-07-30 Shuang Yu , Hong-Yu Zhou , Kai Ma , Cheng Bian , Chunyan Chu , Hanruo Liu , Yefeng Zheng

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

图像与视频处理 · 电气工程与系统科学 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

计算机视觉与模式识别 · 计算机科学 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

图像与视频处理 · 电气工程与系统科学 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Segmentation uncertainty models predict a distribution over plausible segmentations for a given input, which they learn from the annotator variation in the training set. However, in practice these annotations can differ systematically in…

计算机视觉与模式识别 · 计算机科学 2023-03-29 Kilian Zepf , Eike Petersen , Jes Frellsen , Aasa Feragen

Automated detection of anatomical landmarks plays a crucial role in many diagnostic and surgical applications. Progresses in deep learning (DL) methods have resulted in significant performance enhancement in tasks related to anatomical…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Soorena Salari , Hassan Rivaz , Yiming Xiao

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

计算机视觉与模式识别 · 计算机科学 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Performance metrics for medical image segmentation models are used to measure the agreement between the reference annotation and the predicted segmentation. Usually, overlap metrics, such as the Dice, are used as a metric to evaluate the…

图像与视频处理 · 电气工程与系统科学 2024-03-26 Sophie Ostmeier , Brian Axelrod , Jeroen Bertels , Fabian Isensee , Maarten G. Lansberg , Soren Christensen , Gregory W. Albers , Li-Jia Li , Jeremy J. Heit

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

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