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In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…

Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

During spinal fusion surgery, screws are placed close to critical nerves suggesting the need for highly accurate screw placement. Verifying screw placement on high-quality tomographic imaging is essential. C-arm Cone-beam CT (CBCT) provides…

This research considers potential dose increase in target due to cisplatin (Pt) concentration and radiation type. Cisplatin concentrations from 0.003 to 120 mM were used. Monte-Carlo simulation of Linear accelerator (Elekta Synergy) and…

Aiming to measure the difference in arrival times of two coincident gamma-photons with an accuracy in the order of 200 ps, time-of-flight positron emission tomography systems commonly employ silicon photomultipliers (SiPMs) and…

FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…

The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

Monte Carlo simulations have been performed in order to evaluate the efficiencies of several light ions identification techniques. The detection system was composed with layers of scintillating material to measure either the deposited…

Cone Beam CT (CBCT) plays a crucial role in Adaptive Radiation Therapy (ART) by accurately providing radiation treatment when organ anatomy changes occur. However, CBCT images suffer from scatter noise and artifacts, making relying solely…

The CMS Beam Conditions and Radiation Monitoring System, BRM, will support beam tuning, protect the CMS detector from adverse beam conditions, and measure the accumulated dose close to or inside all sub-detectors. It is composed of…

The use of Time-over-Threshold (TOT) for the discrimination between fast neutrons and gamma-rays is advantageous when large number of detection channels are required due to the simplicity of its implementation. However, the results obtained…

Wedemonstratedeep-learningneuralnetwork(NN)-baseddynamicopticalcoherence tomography (DOCT), which generates high-quality logarithmic-intensity-variance (LIV) DOCT images from only four OCT frames. The NN model is trained for tumor spheroid…

Full detector simulation was among the largest CPU consumer in all CERN experiment software stacks for the first two runs of the Large Hadron Collider (LHC). In the early 2010's, the projections were that simulation demands would scale…

The Fast Beam Condition Monitor (FBCM) is a standalone luminometer for the High Luminosity LHC (HL-LHC) program of the CMS Experiment at CERN. The detector is under development and features a new, radiation-hard, front-end…

We evaluate the performance of an LHCb-like detector using a fast simulation of proton-proton collisions at center-of-mass energies of 50 and 100 TeV. The study shows that detector acceptances and resolutions could be similar to those at…

Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…

Vision transformers (ViTs) have dominated computer vision in recent years. However, ViTs are computationally expensive and not well suited for mobile devices; this led to the prevalence of convolutional neural network (CNN) and ViT-based…

The Compton Spectrometer and Imager (COSI) is an upcoming NASA Small Explorer satellite mission, designed for all-sky observations in the soft gamma-ray domain with the use of germanium detectors (GeDs). An active Anticoincidence System…