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Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance…

The magnitude of the pH of the surface of water continues to be a contentious topic in the physical chemistry of aqueous interfaces. Recent theoretical studies have shown little or no preference for the proton to be at the surface compared…

软凝聚态物质 · 物理学 2017-08-02 Federico Giberti , Ali A. Hassanali

Hyperpolarized water can be a valuable aid in protein NMR, leading to amide group 1H polarizations that are orders of magnitude larger than their thermal counterparts. Suitable procedures can exploit this to deliver 2D 1H-15N correlations…

化学物理 · 物理学 2020-04-28 Or Szekely , Gregory Lars Olsen , Mihajlo Novakovic , Rina Rosenzweig , Lucio Frydman

Achieving tritium self-sufficiency is a critical challenge for future fusion power plants. The BABY 1L experiment, part of the LIBRA project at MIT, aims to benchmark tritium breeding and release in molten salt breeder systems under…

We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…

We propose a series of simulations about the potential use of Boron isotopes to trigger neutron-free (aneutronic) nuclear reactions in cancer cells through the interaction with an incoming energetic proton beam, thus resulting in the…

医学物理 · 物理学 2016-08-25 L. Giuffrida , D. Margarone , G. A. P. Cirrone , A. Picciotto , G. Korn

In this work a series of analyses are performed on ab initio molecular dynamics (AIMD) simulations of a hydrated excess proton in water to quantify the relative occurrence of concerted hopping events and <span>rattling</span> events, and…

化学物理 · 物理学 2024-06-19 Christopher Arnsten , Chen Chen , Paul B. Calio , Chenghan Li , Gregory A. Voth

The kinetic energy of H and O nuclei has been studied by path integral molecular dynamics simulations of ice Ih and water at ambient pressure. The simulations were performed by using the q-TIP4P/F model, a point charge empirical potential…

材料科学 · 物理学 2011-09-01 R. Ramirez , C. P. Herrero

This study aims to assess the composition of scattered particles generated in proton therapy for tumours situated proximal to titanium dental implants. The investigation involves decomposing the mixed field and recording Linear Energy…

The emergence of habitable conditions on the early Earth and on rocky exoplanets requires persistent energy sources that can drive both prebiotic chemistry and climate warming under magnetically active young G to M stars. To quantify the…

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

图像与视频处理 · 电气工程与系统科学 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

AWAKE project, a proton driven plasma wakefield acceleration (PDPWA) experiment is approved by CERN. The PDPWA scheme consists of a seeding laser, a drive beam to establish the accelerating wakefields within the plasma cell; and a witness…

加速器物理 · 物理学 2014-06-06 Oznur Mete , Guoxing Xia , Graeme Burt , Swapan Chattopadhyay

Polluted white dwarfs offer a unique way to directly probe the compositions of exoplanetary bodies. We examine the water content of accreted material using the oxygen abundances of 51 highly polluted white dwarfs. Within this sample, we…

Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…

医学物理 · 物理学 2025-08-06 Hunter D. Ellis , Imteaz Rahaman , Apostoli Hillas , Botong Li , Vikren Sarkar , Kai Fu

Metabolic imaging with PET/CT using $^{18}$F-Fludeoxyglucose ($^{18}$F-FDG) as well as other imaging biomarkers has achieved wide acceptance in oncology, cardiology and neurology not only because of the unique metabolic information…

医学物理 · 物理学 2020-06-09 Zhenzhou Deng , Xin Zhao , Anyi Li

Various concentrations (8{\div}300 mmol/L) of NaCl, KCl and NaCl + KCl aqueous solutions were investigated using the positron annihilation lifetime spectroscopy (PALS). A strong dependence of the o-Ps intensity as a function of solution…

The missing mass spectroscopy of $\Xi^{-}$ hypernuclei with the $(K^{-},K^{+})$ reaction is planned to be performed at the J-PARC K1.8 beam line by using a new magnetic spectrometer, Strangeness $-2$ Spectrometer (S-2S). A $\v{C}$cerenkov…

仪器与探测器 · 物理学 2016-07-11 T. Gogami , N. Amano , S. Kanatsuki , T. Nagae , K. Takenaka

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

Proton therapy's full potential is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatment planning. Spatiotemporal Emission Reconstruction from…

Proton therapy is nowadays becoming a wide spread clinical practice in cancer therapy and sophisticated treatment planning systems are routinely used to exploit at best the ballistic properties of charged particles. The information on the…

医学物理 · 物理学 2015-05-14 S. Braccini , A. Ereditato , I. Kreslo , U. Moser , C. Pistillo , P. Scampoli , S. Studer