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Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

定量方法 · 定量生物学 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

计算机视觉与模式识别 · 计算机科学 2024-01-02 Christoph Reich , Tim Prangemeier , André O. Françani , Heinz Koeppl

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

计算机视觉与模式识别 · 计算机科学 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Wood comprises different cell types, such as fibers, tracheids and vessels, defining its properties. Studying cells' shape, size, and arrangement in microscopy images is crucial for understanding wood characteristics. Typically, this…

计算机视觉与模式识别 · 计算机科学 2024-06-19 Saqib Qamar , Abu Imran Baba , Stéphane Verger , Magnus Andersson

Accurate segmentation and precise morphological analysis of neuronal cells in fluorescence microscopy images are crucial steps in neuroscience and biomedical imaging applications. However, this process is labor-intensive and time-consuming,…

图像与视频处理 · 电气工程与系统科学 2025-10-23 Banan Alnemri , Arwa Basbrain

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

图像与视频处理 · 电气工程与系统科学 2022-11-29 Royden Wagner , Karl Rohr

Microscopy imaging techniques are instrumental for characterization and analysis of biological structures. As these techniques typically render 3D visualization of cells by stacking 2D projections, issues such as out-of-plane excitation and…

图像与视频处理 · 电气工程与系统科学 2023-02-16 Amirkoushyar Ziabari , Derek C. Rose , Abbas Shirinifard , David Solecki

Fluorescence microscopy is a widely used method among cell biologists for studying the localization and co-localization of fluorescent protein. For microbial cell biologists, these studies often include tedious and time-consuming manual…

计算机视觉与模式识别 · 计算机科学 2020-09-29 Jonathan Reiner , Guy Azran , Gal Hyams

This work examines the use of a fully convolutional net (FCN) to find an image segment, given a pixel within this segment region. The net receives an image, a point in the image and a region of interest (RoI ) mask. The net output is a…

计算机视觉与模式识别 · 计算机科学 2019-02-26 Sagi Eppel

Melanoma is one of the most serious skin cancers that can occur in any part of the human skin. Early diagnosis of melanoma lesions will significantly increase their chances of being cured. Improving melanoma segmentation will help doctors…

图像与视频处理 · 电气工程与系统科学 2023-01-12 Mohamad Taghizadeh , Karim Mohammadi

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

定量方法 · 定量生物学 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

The expanding applications, utilized by more users, enhance hardware performance and further develop cloud systems for big data processing. This leads to numerous unexplored deep learning applications, especially in advanced computer vision…

计算工程、金融与科学 · 计算机科学 2024-05-07 P. Veysi , M. Adeli , N. Peirov Naziri

Automatic detection of dicentric chromosomes is an essential step to estimate radiation exposure and development of end to end emergency bio dosimetry systems. During accidents, a large amount of data is required to be processed for…

计算机视觉与模式识别 · 计算机科学 2022-04-19 Angad Singh Wadhwa , Nikhil Tyagi , Pinaki Roy Chowdhury

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

计算机视觉与模式识别 · 计算机科学 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Manual peripheral blood smear (PBS) analysis is labor intensive and subjective. While deep learning offers a promising alternative, a systematic evaluation of state of the art models such as YOLOv11 for fine grained PBS detection is still…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Mohamad Abou Ali , Mariam Abdulfattah , Baraah Al Hussein , Fadi Dornaika , Ali Cherry , Mohamad Hajj-Hassan , Lara Hamawy

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method. The image processing…

医学物理 · 物理学 2014-01-06 Dandan Hu , Pinaki Sarder , Peter Ronhovde , Sandra Orthaus , Samuel Achilefu , Zohar Nussinov

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

图像与视频处理 · 电气工程与系统科学 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Convolutional neural networks (CNN) have achieved state of the art performance on both classification and segmentation tasks. Applying CNNs to microscopy images is challenging due to the lack of datasets labeled at the single cell level. We…

计算机视觉与模式识别 · 计算机科学 2017-05-25 Oren Z. Kraus , Lei Jimmy Ba , Brendan Frey
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