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Domain generalization in computational histopathology is hindered by heterogeneity in whole slide images (WSIs), caused by variations in tissue preparation, staining, and imaging conditions across institutions. Unlike machine learning…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Hikmat Khan , Syed Farhan Alam Zaidi , Pir Masoom Shah , Kiruthika Balakrishnan , Rabia Khan , Muhammad Waqas , Jia Wu

Machine learning algorithms have revolutionized different fields, including natural language processing, computer vision, signal processing, and medical data processing. Despite the excellent capabilities of machine learning algorithms in…

图像与视频处理 · 电气工程与系统科学 2022-12-07 Gita Sarafraz , Armin Behnamnia , Mehran Hosseinzadeh , Ali Balapour , Amin Meghrazi , Hamid R. Rabiee

We have tested recently published foundation models for histopathology for image retrieval. We report macro average of F1 score for top-1 retrieval, majority of top-3 retrievals, and majority of top-5 retrievals. We perform zero-shot…

图像与视频处理 · 电气工程与系统科学 2024-09-13 Saghir Alfasly , Ghazal Alabtah , Sobhan Hemati , Krishna Rani Kalari , H. R. Tizhoosh

Machine learning-based Android malware detectors often fail in real-world deployment due to domain shift, where models trained on one data source perform poorly on applications from another. This paper presents a comprehensive study on the…

机器学习 · 计算机科学 2026-05-15 Md Rafid Islam

Performance on benchmark datasets has drastically improved with advances in deep learning. Still, cross-dataset generalization performance remains relatively low due to the domain shift that can occur between two different datasets. This…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Alexandra Carlson , Katherine A. Skinner , Ram Vasudevan , Matthew Johnson-Roberson

Due to the recent advancements in machine vision, digital pathology has gained significant attention. Histopathology images are distinctly rich in visual information. The tissue glass slide images are utilized for disease diagnosis.…

图像与视频处理 · 电气工程与系统科学 2020-11-02 Danial Maleki , Mehdi Afshari , Morteza Babaie , H. R. Tizhoosh

Medical image analysis (MedIA) has become an essential tool in medicine and healthcare, aiding in disease diagnosis, prognosis, and treatment planning, and recent successes in deep learning (DL) have made significant contributions to its…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Jee Seok Yoon , Kwanseok Oh , Yooseung Shin , Maciej A. Mazurowski , Heung-Il Suk

In recent years, numerous domain adaptive strategies have been proposed to help deep learning models overcome the challenges posed by domain shift. However, even unsupervised domain adaptive strategies still require a large amount of target…

图像与视频处理 · 电气工程与系统科学 2024-07-11 Sumayya Inayat , Nimra Dilawar , Waqas Sultani , Mohsen Ali

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

图像与视频处理 · 电气工程与系统科学 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

In machine learning, research has traditionally focused on model development, with relatively less attention paid to training data. As model architectures have matured and marginal gains from further refinements diminish, data quality has…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Pei-Han Chen , Szu-Chi Chung

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Multi-source CT-scan classification suffers from domain shifts that impair cross-source generalization. While preprocessing pipelines combining Spatial-Slice Feature Learning (SSFL++) and Kernel-Density-based Slice Sampling (KDS) have shown…

图像与视频处理 · 电气工程与系统科学 2025-07-29 Chia-Ming Lee , Bo-Cheng Qiu , Ting-Yao Chen , Ming-Han Sun , Fang-Ying Lin , Jung-Tse Tsai , I-An Tsai , Yu-Fan Lin , Chih-Chung Hsu

While Wi-Fi sensing offers a compelling, privacy-preserving alternative to cameras, its practical utility has been fundamentally undermined by a lack of robustness across domains. Models trained in one setup fail to generalize to new…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Cheng Jiang , Yihe Yan , Yanxiang Wang , Chun Tung Chou , Wen Hu

Both limited annotation and domain shift are prevalent challenges in medical image segmentation. Traditional semi-supervised segmentation and unsupervised domain adaptation methods address one of these issues separately. However, the…

计算机视觉与模式识别 · 计算机科学 2025-06-02 Qinghe Ma , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

The automated analysis of medical images is currently limited by technical and biological noise and bias. The same source tissue can be represented by vastly different images if the image acquisition or processing protocols vary. For an…

Atypical mitotic figures (AMFs) are clinically relevant indicators of abnormal cell division, yet their reliable detection remains challenging due to morphological ambiguity and scanner variability. In this work, we investigated three…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Biwen Meng , Xi Long , Jingxin Liu

Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

计算机视觉与模式识别 · 计算机科学 2024-03-27 Eva Pachetti , Sotirios A. Tsaftaris , Sara Colantonio

The MIDOG 2025 challenge extends prior work on mitotic figure detection by introducing a new Track 2 on atypical mitosis classification. This task aims to distinguish normal from atypical mitotic figures in histopathology images, a…