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Mitotic figure detection in histology images is a hard-to-define, yet clinically significant task, where labels are generated with pathologist interpretations and where there is no ``gold-standard'' independent ground-truth. However, it is…

计算机视觉与模式识别 · 计算机科学 2023-10-09 Cagla Deniz Bahadir , Benjamin Liechty , David J. Pisapia , Mert R. Sabuncu

The integration of machine learning (ML) models enhances the efficiency, affordability, and reliability of feature detection in microscopy, yet their development and applicability are hindered by the dependency on scarce and often flawed…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Matthew J. Lynch , Ryan Jacobs , Gabriella Bruno , Priyam Patki , Dane Morgan , Kevin G. Field

In multi-center randomized clinical trials imaging data can be diverse due to acquisition technology or scanning protocols. Models predicting future outcome of patients are impaired by this data heterogeneity. Here, we propose a prediction…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Matthias Perkonigg , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Ahmed Ba-Ssalamah , Georg Langs

Deep learning models tend to underperform in the presence of domain shifts. Domain transfer has recently emerged as a promising approach wherein images exhibiting a domain shift are transformed into other domains for augmentation or…

图像与视频处理 · 电气工程与系统科学 2022-10-27 Weinan Song , Gaurav Fotedar , Nima Tajbakhsh , Ziheng Zhou , Lei He , Xiaowei Ding

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

图像与视频处理 · 电气工程与系统科学 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Domain shift is a well known problem where a model trained on a particular domain (source) does not perform well when exposed to samples from a different domain (target). Unsupervised methods that can adapt to domain shift are highly…

计算机视觉与模式识别 · 计算机科学 2021-08-04 Botos Csaba , Xiaojuan Qi , Arslan Chaudhry , Puneet Dokania , Philip Torr

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

计算机视觉与模式识别 · 计算机科学 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…

计算机视觉与模式识别 · 计算机科学 2021-11-19 Thong Vo , Naimul Khan

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

计算机视觉与模式识别 · 计算机科学 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Domain shifts in medical image segmentation, particularly when data comes from different centers, pose significant challenges. Intra-center variability, such as differences in scanner models or imaging protocols, can cause domain shifts as…

图像与视频处理 · 电气工程与系统科学 2026-03-24 Jin Hong , Bo Liu

Source-free test-time adaptation for medical image segmentation aims to enhance the adaptability of segmentation models to diverse and previously unseen test sets of the target domain, which contributes to the generalizability and…

计算机视觉与模式识别 · 计算机科学 2023-10-19 Yanyu Ye , Zhenxi Zhang , Wei Wei , Chunna Tian

Mitotic count (MC) is an important histological parameter for cancer diagnosis and grading, but the manual process for obtaining MC from whole-slide histopathological images is very time-consuming and prone to error. Therefore, deep…

计算机视觉与模式识别 · 计算机科学 2022-03-01 Chawan Piansaddhayanon , Sakun Santisukwongchote , Shanop Shuangshoti , Qingyi Tao , Sira Sriswasdi , Ekapol Chuangsuwanich

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Multi contrast MRI synthesis is inherently challenging due to the complex and nonlinear relationships among different contrasts. Each MRI contrast highlights unique tissue properties, but their complementary information is difficult to…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Sanuwani Dayarathna , Himashi Peiris , Kh Tohidul Islam , Tien-Tsin Wong , Zhaolin Chen

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

计算机视觉与模式识别 · 计算机科学 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Object detection models trained on a source domain often exhibit significant performance degradation when deployed in unseen target domains, due to various kinds of variations, such as sensing conditions, environments and data…

计算机视觉与模式识别 · 计算机科学 2026-04-10 Saniya M. Deshmukh , Kailash A. Hambarde , Hugo Proença

Magnetic Resonance Imaging (MRI) scans acquired from different scanners or institutions often suffer from domain shifts owing to variations in hardware, protocols, and acquisition parameters. This discrepancy degrades the performance of…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Mohd Usama , Belal Ahmad , Faleh Menawer R Althiyabi

Domain shift in histopathology, often caused by differences in acquisition processes or data sources, poses a major challenge to the generalization ability of deep learning models. Existing methods primarily rely on modeling statistical…

计算机视觉与模式识别 · 计算机科学 2026-03-30 Kieu-Anh Truong Thi , Huy-Hieu Pham , Duc-Trong Le

Both limited annotation and domain shift are prevalent challenges in medical image segmentation. Traditional semi-supervised segmentation and unsupervised domain adaptation methods address one of these issues separately. However, the…

计算机视觉与模式识别 · 计算机科学 2024-08-19 Qinghe Ma , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao