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The transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of paramount importance to the controlling and combating of coronavirus disease 2019 (COVID-19) pandemic. Currently, near 15,000 SARS-CoV-2…

基因组学 · 定量生物学 2020-08-21 Rui Wang , Yuta Hozumi , Yong-Hui Zheng , Changchuan Yin , Guo-Wei Wei

The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December…

基因组学 · 定量生物学 2020-03-25 Changchuan Yin

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been mutating since it was first sequenced in early January 2020. The genetic variants have developed into a few distinct clusters with different properties. Since the…

基因组学 · 定量生物学 2020-07-28 Rui Wang , Jiahui Chen , Kaifu Gao , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Coronavirus disease 2019 (CoViD-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Among many symptoms, cough, fever and tiredness are the most common. People over 60 years old and with…

动力系统 · 数学 2021-08-25 João P. S. Maurício de Carvalho , Beatriz Moreira-Pinto

A novel bioinspired metaheuristic is proposed in this work, simulating how the coronavirus spreads and infects healthy people. From an initial individual (the patient zero), the coronavirus infects new patients at known rates, creating new…

A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dynamics to provide…

Proteins play a key role in facilitating the infectiousness of the 2019 novel coronavirus. A specific spike protein enables this virus to bind to human cells, and a thorough understanding of its 3-dimensional structure is therefore critical…

生物大分子 · 定量生物学 2020-10-28 Samuel W. K. Wong

In an increasingly interconnected world, a key scientific challenge is to examine mechanisms that lead to the widespread propagation of contagions, such as misinformation and pathogens, and identify risk factors that can trigger large-scale…

社会与信息网络 · 计算机科学 2024-09-27 Mansi Sood , Hejin Gu , Rashad Eletreby , Swarun Kumar , Chai Wah Wu , Osman Yagan

The reason of significantly higher transmissibility of SARS Covid (2019 CoV-2) compared to SARS Covid (2003 CoV) and MERS Covid (2012 MERS) can be attributed to mutations reported in structural proteins, and the role played by…

生物大分子 · 定量生物学 2022-02-25 Raju Hazari , P Pal Chaudhuri

At the end of 2020, policy responses to the SARS-CoV-2 outbreak have been shaken by the emergence of virus variants, impacting public health and policy measures worldwide. The emergence of these strains suspected to be more contagious, more…

神经与进化计算 · 计算机科学 2021-02-25 Aymeric Vie

The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…

物理与社会 · 物理学 2019-10-02 Wei Wang , Quan-Hui Liu , Junhao Liang , Yanqing Hu , Tao Zhou

A world-wide COVID-19 pandemic intensified strongly the studies of molecular mechanisms related to the coronaviruses. The origin of coronaviruses and the risks of human-to-human, animal-to-human, and human-to-animal transmission of…

其他定量生物学 · 定量生物学 2021-08-25 Vladimir R. Chechetkin , Vasily V. Lobzin

Phase transition theory, implemented quantitatively by thermodynamic scaling, has explained the evolution of Coronavirus extremely high contagiousness caused by a few key mutations from CoV2003 to CoV2019 identified among hundreds, as well…

其他定量生物学 · 定量生物学 2023-10-05 J. C. Phillips

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

种群与进化 · 定量生物学 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared for future waves of infections. The last three waves of…

种群与进化 · 定量生物学 2022-10-19 Jiahui Chen , Rui Wang , Yuta Hozumi , Gengzhuo Liu , Yuchi Qiu , Xiaoqi Wei , Guo-Wei Wei

The novel coronavirus (2019-nCoV) is a recently emerged human pathogen that has spread widely since January 2020. Initially, the basic reproductive number, R0, was estimated to be 2.2 to 2.7. Here we provide a new estimate of this quantity.…

种群与进化 · 定量生物学 2020-02-11 Steven Sanche , Yen Ting Lin , Chonggang Xu , Ethan Romero-Severson , Nicolas W. Hengartner , Ruian Ke

Human behavior is a dynamic process that evolves with experience. Understanding the evolution of individual's risk propensity is critical to design public health interventions to propitiate the adoption of better biosecurity protocols and…

Compartmental epidemiological models categorize individuals based on their disease status, such as the SEIRD model (Susceptible-Exposed-Infected-Recovered-Dead). These models determine the parameters that influence the magnitude of an…

The appearance of the coronavirus (COVID-19) in late 2019 has dominated the news in the last few months as it developed into a pandemic. In many mathematics and physics classrooms, instructors are using the time series of the number of…

物理教育 · 物理学 2020-07-24 Paulo H. Acioli

Infectious pathogens often propagate by superspreading, which focusses onward transmission on disproportionately few infected individuals. At the same time, infector-infectee pairs tend to have more similar transmission potentials than…

种群与进化 · 定量生物学 2025-09-22 Noah Silva de Leonardi , Benjamin D. Dalziel