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Breast cancer is a leading cause of cancer-related mortality worldwide, and timely accurate diagnosis is critical to improving survival outcomes. While convolutional neural networks (CNNs) have demonstrated strong performance on…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Aditya Shribhagwan Khandelwal , Mohammad Samar Ansari , Asra Aslam

The medical image is characterized by the inter-class indistinction, high variability, and noise, where the recognition of pixels is challenging. Unlike previous self-attention based methods that capture context information from one level,…

计算机视觉与模式识别 · 计算机科学 2019-11-26 Fei Ding , Gang Yang , Jinlu Liu , Jun Wu , Dayong Ding , Jie Xv , Gangwei Cheng , Xirong Li

The diagnosis and prognosis of cancer are typically based on multi-modal clinical data, including histology images and genomic data, due to the complex pathogenesis and high heterogeneity. Despite the advancements in digital pathology and…

定量方法 · 定量生物学 2024-04-15 Zeyu Zhang , Yuanshen Zhao , Jingxian Duan , Yaou Liu , Hairong Zheng , Dong Liang , Zhenyu Zhang , Zhi-Cheng Li

Complex networks can be used to analyze structures and systems in the embryo. Not only can we characterize growth and the emergence of form, but also differentiation. The process of differentiation from precursor cell populations to…

定量方法 · 定量生物学 2023-11-30 Bradly Alicea

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…

Understanding the encoding and decoding mechanisms of dynamic neural responses to different visual stimuli is an important topic in exploring how the brain represents visual information. Currently, hierarchically deep neural networks (DNNs)…

神经元与认知 · 定量生物学 2025-12-24 Jingyi Feng , Xiang Feng

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

计算机视觉与模式识别 · 计算机科学 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

计算机视觉与模式识别 · 计算机科学 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

图像与视频处理 · 电气工程与系统科学 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

Graph Auto-Encoders (GAEs) are powerful tools for graph representation learning. In this paper, we develop a novel Hierarchical Cluster-based GAE (HC-GAE), that can learn effective structural characteristics for graph data analysis. To this…

机器学习 · 计算机科学 2024-05-24 Zhuo Xu , Lu Bai , Lixin Cui , Ming Li , Yue Wang , Edwin R. Hancock

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Spatial transcriptomics has the potential to transform our understanding of RNA expression in tissues. Classical array-based technologies produce multiple-cell-scale measurements requiring deconvolution to recover single cell information.…

Graph representation learning has made major strides over the past decade. However, in many relational domains, the input data are not suited for simple graph representations as the relationships between entities go beyond pairwise…

机器学习 · 计算机科学 2021-01-20 Balasubramaniam Srinivasan , Da Zheng , George Karypis

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

图像与视频处理 · 电气工程与系统科学 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

计算机视觉与模式识别 · 计算机科学 2021-01-01 Mo Zhang , Quanzheng Li

Accurate segmentation of brain tumors from 3D multimodal MRI is vital for diagnosis and treatment planning across diverse brain tumors. This paper addresses the challenges posed by the BraTS 2023, presenting a unified transfer learning…

图像与视频处理 · 电气工程与系统科学 2024-12-12 Ramy A. Zeineldin , Franziska Mathis-Ullrich

In clinical practice, human radiologists actually review medical images with high resolution monitors and zoom into region of interests (ROIs) for a close-up examination. Inspired by this observation, we propose a hierarchical graph neural…

图像与视频处理 · 电气工程与系统科学 2019-12-17 Hao Du , Jiashi Feng , Mengling Feng

Microscopic examination of tissues or histopathology is one of the diagnostic procedures for detecting colorectal cancer. The pathologist involved in such an examination usually identifies tissue type based on texture analysis, especially…

图像与视频处理 · 电气工程与系统科学 2020-04-06 Srinath Jayachandran , Ashlin Ghosh

Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Chen Zhang , Yilu An , Ying Chen , Hao Li , Xitong Ling , Lihao Liu , Junjun He , Yuxiang Lin , Zihui Wang , Rongshan Yu