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While electronic health records (EHRs) are widely used across various applications in healthcare, most applications use the EHRs in their raw (tabular) format. Relying on raw or simple data pre-processing can greatly limit the performance…

机器学习 · 计算机科学 2024-03-28 Fahmida Liza Piya , Mehak Gupta , Rahmatollah Beheshti

Electronic health records (EHR) are widely believed to hold a profusion of actionable insights, encrypted in an irregular, semi-structured format, amidst a loud noise background. To simplify learning patterns of health and disease, medical…

计算与语言 · 计算机科学 2022-12-13 David A. Bloore , Romane Gauriau , Anna L. Decker , Jacob Oppenheim

Panoramic image segmentation in computational pathology presents a remarkable challenge due to the morphologically complex and variably scaled anatomy. For instance, the intricate organization in kidney pathology spans multiple layers, from…

图像与视频处理 · 电气工程与系统科学 2024-07-02 Ruining Deng , Quan Liu , Can Cui , Tianyuan Yao , Juming Xiong , Shunxing Bao , Hao Li , Mengmeng Yin , Yu Wang , Shilin Zhao , Yucheng Tang , Haichun Yang , Yuankai Huo

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Bo Hu , Ye Tang , Eric I-Chao Chang , Yubo Fan , Maode Lai , Yan Xu

Cell detection is a fundamental task in computational pathology that can be used for extracting high-level medical information from whole-slide images. For accurate cell detection, pathologists often zoom out to understand the tissue-level…

Histopathology image segmentation is essential for delineating tissue structures in skin cancer diagnostics, but modeling spatial context and inter-tissue relationships remains a challenge, especially in regions with overlapping or…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Shravan Venkatraman , Muthu Subash Kavitha , Joe Dhanith P R , V Manikandarajan , Jia Wu

Robust segmentation for non-elongated tissues in medical images is hard to realize due to the large variation of the shape, size, and appearance of these tissues in different patients. In this paper, we present an end-to-end trainable deep…

图像与视频处理 · 电气工程与系统科学 2020-04-06 Qian Yu , Yinghuan Shi , Yefeng Zheng , Yang Gao , Jianbing Zhu , Yakang Dai

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

机器学习 · 计算机科学 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

Recent advances in biological technologies, such as multi-way chromosome conformation capture (3C), require development of methods for analysis of multi-way interactions. Hypergraphs are mathematically tractable objects that can be utilized…

定量方法 · 定量生物学 2023-07-19 Joshua Pickard , Can Chen , Rahmy Salman , Cooper Stansbury , Sion Kim , Amit Surana , Anthony Bloch , Indika Rajapakse

Bone metastasis analysis is a significant challenge in pathology and plays a critical role in determining patient quality of life and treatment strategies. The microenvironment and specific tissue structures are essential for pathologists…

计算机视觉与模式识别 · 计算机科学 2025-01-29 Yuxuan Chen , Jiawen Li , Huijuan Shi , Yang Xu , Tian Guan , Lianghui Zhu , Yonghong He , Anjia Han

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

图像与视频处理 · 电气工程与系统科学 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

We present HARP, a novel method for learning low dimensional embeddings of a graph's nodes which preserves higher-order structural features. Our proposed method achieves this by compressing the input graph prior to embedding it, effectively…

社会与信息网络 · 计算机科学 2017-11-17 Haochen Chen , Bryan Perozzi , Yifan Hu , Steven Skiena

Purpose: Accurate identification of hepatocystic anatomy is critical to preventing surgical complications during laparoscopic cholecystectomy. Deep learning models often struggle with occlusions, long-range dependencies, and capturing the…

计算机视觉与模式识别 · 计算机科学 2025-11-21 Yihan Li , Nikhil Churamani , Maria Robu , Imanol Luengo , Danail Stoyanov

Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Ying Xiao , Shimiao Tang , Xitong Ling , Weiming Chen , Jun Wang , Jiawen Li , Huaitian Yuan , Jianghui Yang , Bowen Li , Huan Li , Yiting Meng , Tian Guan , Yonghong He , Hongfang Yin

Many researchers both in academia and industry have long been interested in the stock market. Numerous approaches were developed to accurately predict future trends in stock prices. Recently, there has been a growing interest in utilizing…

统计金融 · 定量金融 2019-11-13 Raehyun Kim , Chan Ho So , Minbyul Jeong , Sanghoon Lee , Jinkyu Kim , Jaewoo Kang

We introduce a graph-theoretic approach to extract clusters and hierarchies in complex data-sets in an unsupervised and deterministic manner, without the use of any prior information. This is achieved by building topologically embedded…

数据分析、统计与概率 · 物理学 2014-02-13 Won-Min Song , T. Di Matteo , Tomaso Aste

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

In clinical practice, many diagnosis tasks rely on the identification of cells in histopathology images. While supervised machine learning techniques require labels, providing manual cell annotations is time-consuming due to the large…

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

计算机视觉与模式识别 · 计算机科学 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim

The topological (or graph) structures of real-world networks are known to be predictive of multiple dynamic properties of the networks. Conventionally, a graph structure is represented using an adjacency matrix or a set of hand-crafted…

社会与信息网络 · 计算机科学 2016-10-21 Cheng Li , Xiaoxiao Guo , Qiaozhu Mei