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Radiomics is an exciting new area of texture research for extracting quantitative and morphological characteristics of pathological tissue. However, to date, only single images have been used for texture analysis. We have extended radiomic…

图像与视频处理 · 电气工程与系统科学 2019-06-11 Vishwa S. Parekh , John Laterra , Chetan Bettegowda , Alex E. Bocchieri , Jay J. Pillai , Michael A. Jacobs

Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

图像与视频处理 · 电气工程与系统科学 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

医学物理 · 物理学 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

图像与视频处理 · 电气工程与系统科学 2025-07-22 Zhijin He , Alan B. McMillan

Background: Radiomics shows promise in characterizing glioblastoma, but its added value over clinical and molecular predictors has yet to be proven. This study assessed the added value of conventional radiomics (CR) and deep learning (DL)…

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

计算机视觉与模式识别 · 计算机科学 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

机器学习 · 计算机科学 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Radiomics analysis has achieved great success in recent years. However, conventional Radiomics analysis suffers from insufficiently expressive hand-crafted features. Recently, emerging deep learning techniques, e.g., convolutional neural…

图像与视频处理 · 电气工程与系统科学 2019-10-22 Jiancheng Yang , Rongyao Fang , Bingbing Ni , Yamin Li , Yi Xu , Linguo Li

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

计算机视觉与模式识别 · 计算机科学 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Head and neck cancers are the fifth most common cancer worldwide, and recently, analysis of Positron Emission Tomography (PET) and Computed Tomography (CT) images has been proposed to identify patients with a prognosis. Even though the…

图像与视频处理 · 电气工程与系统科学 2022-12-01 Vajira Thambawita , Andrea M. Storås , Steven A. Hicks , Pål Halvorsen , Michael A. Riegler

The prediction of pancreatic ductal adenocarcinoma therapy response is a clinically challenging and important task in this high-mortality tumour entity. The training of neural networks able to tackle this challenge is impeded by a lack of…

图像与视频处理 · 电气工程与系统科学 2023-03-31 Alexander Ziller , Ayhan Can Erdur , Friederike Jungmann , Daniel Rueckert , Rickmer Braren , Georgios Kaissis

In this work, we develop an attention convolutional neural network (CNN) to segment brain tumors from Magnetic Resonance Images (MRI). Further, we predict the survival rate using various machine learning methods. We adopt a 3D UNet…

图像与视频处理 · 电气工程与系统科学 2021-04-05 Mobarakol Islam , Vibashan VS , V Jeya Maria Jose , Navodini Wijethilake , Uppal Utkarsh , Hongliang Ren

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

机器学习 · 计算机科学 2015-09-29 Mohnish Chakravarti , Tanay Kothari

Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a…

图像与视频处理 · 电气工程与系统科学 2023-01-13 Siteng Chen , Xiyue Wang , Jun Zhang , Liren Jiang , Ning Zhang , Feng Gao , Wei Yang , Jinxi Xiang , Sen Yang , Junhua Zheng , Xiao Han

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

计算工程、金融与科学 · 计算机科学 2025-05-16 Binesh Sadanandan , Vahid Behzadan

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

机器学习 · 计算机科学 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

Multiple Myeloma (MM) is a blood cancer implying bone marrow involvement, renal damages and osteolytic lesions. The skeleton involvement of MM is at the core of the present paper, exploiting radiomics and artificial intelligence to identify…