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The long duration of the COVID-19 pandemic allowed for multiple bursts in the infection and death rates, the so-called epidemic waves. This complex behavior is no longer tractable by simple compartmental model and requires more…

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

机器学习 · 计算机科学 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

Mathematical models are instrumental to forecast the spread of pathogens and to evaluate the effectiveness of non-pharmaceutical measures. A plethora of optimal strategies has been recently developed to minimize either the infected peak…

动力系统 · 数学 2021-11-11 J. Sereno , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

Epidemiological compartmental models are useful for understanding infectious disease propagation and directing public health policy decisions. Calibration of these models is an important step in offering accurate forecasts of disease…

机器学习 · 计算机科学 2023-12-12 Nikunj Gupta , Anh Mai , Azza Abouzied , Dennis Shasha

Downsizing the US public health workforce throughout 2025 amplifies potential risks during public health crises. Expert judgment from public health officials represents a vital information source, distinct from traditional surveillance…

种群与进化 · 定量生物学 2025-08-22 Garrik Hoyt , Eleanor Bergren , Gabrielle String , Thomas McAndrew

Nowadays, time series forecasting is predominantly approached through the end-to-end training of deep learning architectures using error-based objectives. While this is effective at minimizing average loss, it encourages the encoder to…

机器学习 · 计算机科学 2026-03-26 Jiacheng Wang , Liang Fan , Baihua Li , Luyan Zhang

Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…

应用统计 · 统计学 2020-06-02 Stephen A Lauer , Alexandria C Brown , Nicholas G Reich

Accurate forecasting of infectious disease incidence is critical for public health planning and timely intervention. While most data-driven forecasting approaches rely primarily on historical data from a single country, such data are often…

种群与进化 · 定量生物学 2026-01-29 Zacharias Komodromos , Kleanthis Malialis , Artemis Kontou , Panayiotis Kolios

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…

物理与社会 · 物理学 2021-07-26 Hugo Dolan , Riccardo Rastelli

Integrating heterogeneous data sources and expert knowledge is essential for overcoming data scarcity and enhancing estimation accuracy. Two main frameworks naturally arise to perform the integration of these multiple sources: sequential…

统计方法学 · 统计学 2025-11-26 Mario Figueira , David Conesa , Antonio López-Quílez , Håvard Rue

The evolution of the hemagglutinin amino acids sequences of Influenza A virus is studied by a method based on an informational metrics, originally introduced by Rohlin for partitions in abstract probability spaces. This metrics does not…

种群与进化 · 定量生物学 2015-06-03 Raffaella Burioni , Riccardo Scalco , Mario Casartelli

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

统计方法学 · 统计学 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

We consider a remote inference system with multiple modalities, where a multimodal machine learning (ML) model performs real-time inference using features collected from remote sensors. When sensor observations evolve dynamically over time,…

机器学习 · 计算机科学 2026-04-28 Keyuan Zhang , Yin Sun , Bo Ji

Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with…

机器学习 · 计算机科学 2024-04-11 Unnseo Park , Venkatesh Sivaraman , Adam Perer

Performative prediction characterizes environments where predictive models alter the very data distributions they aim to forecast, triggering complex feedback loops. While prior research treats single-agent and multi-agent performativity as…

机器学习 · 统计学 2026-02-04 Zhixian Zhang , Xiaotian Hou , Linjun Zhang

This article describes a new method for estimating weekly incidence (new onset) of symptoms consistent with Influenza and COVID-19, using data from the Flutracking survey. The method mitigates some of the known self-selection and…

统计方法学 · 统计学 2022-09-01 Emily P. Harvey , Joel A. Trent , Frank Mackenzie , Steven M. Turnbull , Dion R. J. O'Neale

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, culture, and experience, suggesting their presence may be…

人工智能 · 计算机科学 2026-03-05 Farhad Abtahi , Mehdi Astaraki , Fernando Seoane

Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of…

Contemporary Epidemiological Surveillance (ES) relies heavily on data analytics. These analytics are critical input for pandemics preparedness networks; however, this input is not integrated into a form suitable for decision makers or…

人工智能 · 计算机科学 2020-08-11 Svetlana Yanushkevich , Vlad Shmerko

Forecasting the future course of epidemics has always been one of the main goals of epidemic modelling. This chapter reviews statistical methods to quantify the accuracy of epidemic forecasts. We distinguish point and probabilistic…

统计方法学 · 统计学 2019-12-19 Leonhard Held , Sebastian Meyer