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Cell monolayers and epithelial tissues display slow dynamics during the liquid-glass transitions, a phenomenon with direct relevance to embryogenesis, tumor metastases, and wound healing. In active cells, persistent motion and cell…

软凝聚态物质 · 物理学 2024-01-25 Meng-Yuan Li , Yan-Wei Li

Elastic models of the glass transition relate the relaxation dynamics and the elastic properties of structural glasses. They are based on the assumption that the relaxation dynamics occurs through activated events in the energy landscape…

软凝聚态物质 · 物理学 2015-08-20 M. Pica Ciamarra , Peter Sollich

Many soft and biological materials display so-called 'soft glassy' dynamics; their constituents undergo anomalous random motions and complex cooperative rearrangements. A recent simulation model of one soft glassy material, a coarsening…

Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…

软凝聚态物质 · 物理学 2019-05-07 Michael Czajkowski , Daniel M. Sussman , M. Cristina Marchetti , M. Lisa Manning

In order to understand the mechanisms for glassy dynamics in biological tissues and shed light on those in non-biological materials, we study the low-temperature disordered phase of 2D vertex-like models. Recently it has been noted that…

软凝聚态物质 · 物理学 2018-05-09 Daniel M. Sussman , M. Paoluzzi , M. Cristina Marchetti , M. Lisa Manning

Observations of glassy dynamics in experiments on confluent cellular tissue have inspired a wealth of computational and theoretical research to model their emergent collective behavior. Initial studies of the physical properties of several…

软凝聚态物质 · 物理学 2024-09-04 Helen S. Ansell , Chengling Li , Daniel M. Sussman

A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

生物物理 · 物理学 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

Understanding the structural dynamics of many-particle glassy systems remains a key challenge in statistical physics. Over the last decade, glassy dynamics has also been reported in biological tissues, but is far from being understood. It…

软凝聚态物质 · 物理学 2024-09-30 Chengling Li , Matthias Merkel , Daniel M. Sussman

The description of activated relaxation of glassy systems in the multidimensional configurational space is a long-standing open problem. We develop a phenomenological description of the out-of-equilibrium dynamics of a model with a rough…

无序系统与神经网络 · 物理学 2014-10-09 Chiara Cammarota , Enzo Marinari

Foams and dense emulsions display complex mechanical behavior, including intermittent rearrangement dynamics, power-law rheology, and slow recovery after perturbation. These effects have long been considered evidence for glassy physics in…

软凝聚态物质 · 物理学 2025-08-01 Amruthesh Thirumalaiswamy , Clary Rodríguez-Cruz , Robert A. Riggleman , John C. Crocker

Generic glass formers exhibit at least two characteristic changes in their relaxation behavior, first to an Arrhenius-type relaxation at some characteristic temperature, and then at a lower characteristic temperature to a super-Arrhenius…

无序系统与神经网络 · 物理学 2012-03-08 H. George E. Hentschel , Smarajit Karmakar , Itamar Procaccia , Jacques Zylberg

We present a three-dimensional lattice-gas model with trivial thermodynamics, but nontrivial dynamics. The model is characterized by each particle having its own random energy landscape. The equilibrium dynamics of the model were…

软凝聚态物质 · 物理学 2012-03-27 Ulf R. Pedersen , Tina Hecksher , Jeppe C. Dyre , Thomas B. Schrøder

In the free energy landscape picture of glassy systems, the slow dynamics characteristic of these systems is believed to be due to the existence of a complicated free-energy landscape with many local minima. We show here that for a…

软凝聚态物质 · 物理学 2009-11-11 Sara Jabbari-Farouji , Gerard H. Wegdam , Daniel Bonn

Measuring, characterizing and modelling the slow dynamics of glassy soft matter is a great challenge, with an impact that ranges from industrial applications to fundamental issues in modern statistical physics, such as the glass transition…

软凝聚态物质 · 物理学 2009-11-11 Luca Cipelletti , Laurence Ramos

Particles undergoing Fickian diffusion within smooth energy landscapes exhibit Gaussian statistics. However, this Gaussian behavior is often elusive in complex liquids, where particle dynamics within spontaneously fluctuating or…

软凝聚态物质 · 物理学 2025-11-12 Vinay Vaibhav , Tamoghna Das , Suman Dutta

During the life of animals, epithelial tissues undergo extensive deformations--first to form organs during embryogensis and later to preserve integrity and function in adulthood. To what extent these deformations resemble that of non-living…

软凝聚态物质 · 物理学 2025-04-23 Urska Andrensek , Matej Krajnc

We identify a link between the glass transition and percolation of mobile regions in configuration space. We find that many hallmarks of glassy dynamics, for example stretched-exponential response functions and a diverging structural…

统计力学 · 物理学 2009-11-13 Gregg Lois , Jerzy Blawzdziewicz , Corey S. O'Hern

As wounds heal, embryos develop, cancer spreads, or asthma progresses, the cellular monolayer undergoes glass transition between solid-like jammed and fluid-like flowing states. During some of these processes, the cells undergo an…

Glasses are amorphous solids whose constituent particles are caged by their neighbors and thus cannot flow. This sluggishness is often ascribed to the free energy landscape containing multiple minima (basins) separated by high barriers.…

无序系统与神经网络 · 物理学 2014-04-29 Patrick Charbonneau , Jorge Kurchan , Giorgio Parisi , Pierfrancesco Urbani , Francesco Zamponi

The dynamical glass transition is typically taken to be the temperature at which a glassy liquid is no longer able to equilibrate on experimental timescales. Consequently, the physical properties of these systems just above or below the…

软凝聚态物质 · 物理学 2017-03-08 Samuel S. Schoenholz , Ekin D. Cubuk , Efthimios Kaxiras , Andrea J. Liu
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