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Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

In the absence of sufficient medication for COVID patients due to the increased demand, disused drugs have been employed or the doses of those available were modified by hospital pharmacists. Some evidences for the use of alternative drugs…

The novel coronavirus (SARS-CoV-2) which causes COVID-19 is an ongoing pandemic. There are ongoing studies with up to hundreds of publications uploaded to databases daily. We are exploring the use-case of artificial intelligence and natural…

信息检索 · 计算机科学 2021-02-16 Yutong Jin , Jie Li , Xinyu Wang , Peiyao Li , Jinjiang Guo , Junfeng Wu , Dawei Leng , Lurong Pan

The world has witnessed unprecedented human and economic loss from the COVID-19 disease, caused by the novel coronavirus SARS-CoV-2. Extensive research is being conducted across the globe to identify therapeutic agents against the…

The integration of machine learning methods into bioinformatics provides particular benefits in identifying how therapeutics effective in one context might have utility in an unknown clinical context or against a novel pathology. We aim to…

机器学习 · 计算机科学 2020-06-29 Semih Cantürk , Aman Singh , Patrick St-Amant , Jason Behrmann

Severe acute respiratory syndrome coronavirus two (SARS-CoV-2), the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, represents an unprecedented global health challenge. Consequently, a large amount of research into…

Coronavirus disease (COVID-19) has been declared as a pandemic by WHO with thousands of cases being reported each day. Numerous scientific articles are being published on the disease raising the need for a service which can organize, and…

Automated information extraction with natural language processing (NLP) tools is required to gain systematic insights from the large number of COVID-19 publications, reports and social media posts, which far exceed human processing…

其他定量生物学 · 定量生物学 2025-06-16 Salma Kazemi Rashed , Rafsan Ahmed , Johan Frid , Sonja Aits

The novel coronavirus disease (COVID-19) began in Wuhan, China, in late 2019 and to date has infected over 148M people worldwide, resulting in 3.12M deaths. On March 10, 2020, the World Health Organisation (WHO) declared it as a global…

信息检索 · 计算机科学 2022-05-31 Sanku Satya Uday , Satti Thanuja Pavani , T. Jaya Lakshmi , Rohit Chivukula

In the past several months, COVID-19 has spread over the globe and caused severe damage to the people and the society. In the context of this severe situation, an effective drug discovery method to generate potential drugs is extremely…

机器学习 · 计算机科学 2021-04-26 Tianyue Cheng , Tianchi Fan , Landi Wang

SARS-COV-2 is a positive single-strand RNA-based macromolecule that has caused the death of more than 6.3 million people since June 2022. Moreover, by disturbing global supply chains through lockdown, the virus has indirectly caused…

生物大分子 · 定量生物学 2022-11-01 Imra Aqeel , Abdul Majid

Drug development is time-consuming and expensive. Repurposing existing drugs for new therapies is an attractive solution that accelerates drug development at reduced experimental costs, specifically for Coronavirus Disease 2019 (COVID-19),…

生物大分子 · 定量生物学 2022-02-11 Xiaoqin Pan , Xuan Lin , Dongsheng Cao , Xiangxiang Zeng , Philip S. Yu , Lifang He , Ruth Nussinov , Feixiong Cheng

The outbreak of COVID-19 caused millions of deaths worldwide, and the number of total infections is still rising. It is necessary to identify some potentially effective drugs that can be used to prevent the development of severe symptoms or…

分子网络 · 定量生物学 2022-09-07 Fan Hu , Jiaxin Jiang , Peng Yin

There have been more than 850,000 confirmed cases and over 48,000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone.…

定量方法 · 定量生物学 2020-05-25 Xiangxiang Zeng , Xiang Song , Tengfei Ma , Xiaoqin Pan , Yadi Zhou , Yuan Hou , Zheng Zhang , George Karypis , Feixiong Cheng

The unprecedented outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), or COVID-19, continues to be a significant worldwide problem. As a result, a surge of new COVID-19 related research has followed suit. The growing…

机器学习 · 计算机科学 2021-07-21 Maksim E. Eren , Nick Solovyev , Chris Hamer , Renee McDonald , Boian S. Alexandrov , Charles Nicholas

The COVID-19 global pandemic has resulted in international efforts to understand, track, and mitigate the disease, yielding a significant corpus of COVID-19 and SARS-CoV-2-related publications across scientific disciplines. As of May 2020,…

信息检索 · 计算机科学 2020-06-18 Andre Esteva , Anuprit Kale , Romain Paulus , Kazuma Hashimoto , Wenpeng Yin , Dragomir Radev , Richard Socher

With the COVID-19 pandemic, there is a growing urgency for medical community to keep up with the accelerating growth in the new coronavirus-related literature. As a result, the COVID-19 Open Research Dataset Challenge has released a corpus…

计算与语言 · 计算机科学 2020-06-04 Virapat Kieuvongngam , Bowen Tan , Yiming Niu

A new coronavirus identified as SARS-CoV-2 virus has brought the world to a state of crisis, causing a major pandemic, claiming more than 433,000 lives and instigating major financial damage to the global economy. Despite current efforts,…

生物大分子 · 定量生物学 2020-06-18 Mohsen Chitsaz

Amid the pandemic of 2019 novel coronavirus disease (COVID-19) infected by SARS-CoV-2, a vast amount of drug research for prevention and treatment has been quickly conducted, but these efforts have been unsuccessful thus far. Our objective…

定量方法 · 定量生物学 2022-02-03 Kanglin Hsieh , Yinyin Wang , Luyao Chen , Zhongming Zhao , Sean Savitz , Xiaoqian Jiang , Jing Tang , Yejin Kim

The coronavirus disease (COVID-19) has claimed the lives of over 350,000 people and infected more than 6 million people worldwide. Several search engines have surfaced to provide researchers with additional tools to find and retrieve…

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