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We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Active soft matter frequently shows motility-induced phase separation (MIPS), where self-propelled particles condensate into clusters with an inner liquid-like structure. Such activity may also result in motility-induced crystallization…

软凝聚态物质 · 物理学 2026-02-24 Max Philipp Holl , Alina Barbar Steinberg , Uwe Thiele

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

We present a computational study of sliding between gold clusters and a highly oriented pyrolytic graphite substrate, a material system that exhibits ultra-low friction due to structural lubricity. By means of molecular dynamics, it is…

计算物理 · 物理学 2023-03-27 Wai H. Oo , Mehmet Z. Baykara , Hongyu Gao

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

软凝聚态物质 · 物理学 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

种群与进化 · 定量生物学 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

We consider collective dynamics of self-propelling particles in two dimensions. They can align themselves according to the direction of propulsion of their neighbours, together with a random perturbation (i.e. rotational fluctuation). They…

软凝聚态物质 · 物理学 2019-04-01 Shubhashis Rana , Md. Samsuzzaman , Arnab Saha

Cell invasion and spatial pattern formation are two distinct manifestations of cellular self-organisation in development, regeneration, and disease. Here, we develop and analyse a unified theoretical framework that links these two seemingly…

组织与器官 · 定量生物学 2026-04-30 Carles Falcó , Samuel W. S. Johnson , Mohit P. Dalwadi , Philip K. Maini

We propose a minimal off-lattice model of living organisms where just a very few dynamical rules of growth are assumed. The stable coexistence of many clusters is detected when we replace the global restriction rule by a locally applied…

物理与社会 · 物理学 2021-08-19 B. F. de Oliveira , M. V. de Moraes , D. Bazeia , A. Szolnoki

Chirality in shape and motility can evolve rapidly in microbes and cancer cells. To determine how chirality affects cell fitness, we developed a model of chiral growth in compact aggregates such as microbial colonies and solid tumors. Our…

种群与进化 · 定量生物学 2020-07-14 Ashish B. George , Kirill S. Korolev

We show that a scaling approach successfully characterizes clustering and intermittency in space and time, in systems of noninteracting particles driven by fluctuating surfaces. We study both the steady state and the approach to it, for…

软凝聚态物质 · 物理学 2019-01-15 Tapas Singha , Mustansir Barma

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

凝聚态物理 · 物理学 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

The behaviour and functioning of a variety of complex physical and biological systems depend on the spatial organisation of their constituent units, and on the presence and formation of clusters of functionally similar or related…

物理与社会 · 物理学 2023-08-16 Silvia Rognone , Vincenzo Nicosia

There are two modes by which clusters of aggregating particles can coalesce: The clusters can merge either (i) by the Ostwald ripening process in which particles diffuse from one cluster to the other whilst the cluster centres remain…

软凝聚态物质 · 物理学 2014-05-13 Andrey Pototsky , Uwe Thiele , Andrew J. Archer

The persistent motion of bacteria produces clusters with a stationary cluster size distribution (CSD). Here we develop a minimal model for bacteria in a narrow channel to assess the relative importance of motility diversity (i.e.…

软凝聚态物质 · 物理学 2020-11-19 Pablo de Castro , Saulo Diles , Rodrigo Soto , Peter Sollich

Dense monolayers of living cells display intriguing relaxation dynamics, reminiscent of soft and glassy materials close to the jamming transition, and migrate collectively when space is available, as in wound healing or in cancer invasion.…

We study the evolution of a collection of individuals subject to Brownian diffusion, reproduction and disappearance. In particular, we focus on the case where the individuals are initially prepared at equilibrium within a confined geometry.…

统计力学 · 物理学 2015-01-06 Andrea Zoia , Eric Dumonteil , Alain Mazzolo , Clélia de Mulatier , Alberto Rosso

This work focuses on the formation of mating aggregates in zooplankton. In particular, sexual encounters are behaviourally supported by males actively swimming in search for females, and approaching them for mating once they are found.…

种群与进化 · 定量生物学 2022-05-19 Ron Shnapp , François-Gaël Michalec , Markus Holzner

Depletion-induced aggregation of rods enhanced by clustering is observed to produce a novel model of attractive pairs of rods separated by a line of spheres in a quasi-2D, vertically-shaken, granular gas of rods and spheres. We show that…

软凝聚态物质 · 物理学 2016-08-08 Gustavo M. Rodríguez-Liñán , Yuri Nahmad-Molinari , Gabriel Pérez-Ángel

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

细胞行为 · 定量生物学 2018-08-02 Christèle Etchegaray , Nicolas Meunier