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相关论文: Sample size re-estimation in Phase 2 Dose-Finding:…

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We consider a Bayesian persuasion or information design problem where the sender tries to persuade the receiver to take a particular action via a sequence of signals. This we model by considering multi-phase trials with different…

理论经济学 · 经济学 2021-11-24 Shih-Tang Su , Vijay G. Subramanian , Grant Schoenebeck

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for all'' approach for causal inference with survival outcomes…

统计方法学 · 统计学 2021-12-21 Shuxi Zeng , Fan Li , Liangyuan Hu , Fan Li

Surrogate markers are often employed in clinical trials to replace primary outcomes that may be difficult, expensive, or time-consuming to measure directly. These markers can accelerate the evaluation of new treatments, provided they…

统计方法学 · 统计学 2026-03-17 Pietro Carlotti , Layla Parast

Propensity score (PS) methods are widely used to estimate treatment effects in non-randomized studies. Variance is typically estimated using sandwich or bootstrap methods, which can either treat the PS as estimated or fixed. The latter is…

统计方法学 · 统计学 2025-11-17 Baoshan Zhang , Sean M. O'Brien , Yuan Wu , Laine E. Thomas

We consider supervised dimension reduction problems, namely to identify a low dimensional projection of the predictors $\-x$ which can retain the statistical relationship between $\-x$ and the response variable $y$. We follow the idea of…

统计计算 · 统计学 2019-10-31 Xin Cai , Guang Lin , Jinglai Li

Bayesian simulation-based inference (SBI) methods are used in statistical models where simulation is feasible but the likelihood is intractable. Standard SBI methods can perform poorly in cases of model misspecification, and there has been…

统计方法学 · 统计学 2025-04-15 Wang Yuyan , Michael Evans , David J. Nott

We consider the problem of state estimation from limited discrete and noisy measurements. In particular, we focus on modal state estimation, which approximates the unknown state of the system within a prescribed basis. We estimate the…

数值分析 · 数学 2025-05-08 Lev Kakasenko , Alen Alexanderian , Mohammad Farazmand , Arvind K. Saibaba

In Bayesian statistics, horseshoe prior has attracted increasing attention as an approach to the sparse estimation. The estimation accuracy of compressed sensing with the horseshoe prior is evaluated by statistical mechanical method. It is…

无序系统与神经网络 · 物理学 2023-03-29 Yasushi Nagano , Koji Hukushima

An informative sampling design leads to unit inclusion probabilities that are correlated with the response variable of interest. However, multistage sampling designs may also induce higher order dependencies, which are typically ignored in…

统计方法学 · 统计学 2019-01-23 Matthew R. Williams , Terrance D. Savitsky

The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical…

统计方法学 · 统计学 2024-09-11 Kaoru Babasaki , Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn

Predictive models ground many state-of-the-art developments in statistical brain image analysis: decoding, MVPA, searchlight, or extraction of biomarkers. The principled approach to establish their validity and usefulness is…

定量方法 · 定量生物学 2017-06-26 Gaël Varoquaux

Bayesian hypothesis tests leverage posterior probabilities, Bayes factors, or credible intervals to inform data-driven decision making. We propose a framework for power curve approximation with such hypothesis tests. We present a fast…

统计方法学 · 统计学 2024-10-08 Luke Hagar , Nathaniel T. Stevens

Determining the sample size of an experiment can be challenging, even more so when incorporating external information via a prior distribution. Such information is increasingly used to reduce the size of the control group in randomized…

应用统计 · 统计学 2019-07-10 Beat Neuenschwander , Sebastian Weber , Heinz Schmidli , Anthony O'Hagan

We consider the nonparametric regression problem with multiple predictors and an additive error, where the regression function is assumed to be coordinatewise nondecreasing. We propose a Bayesian approach to make an inference on the…

统计理论 · 数学 2022-11-24 Kang Wang , Subhashis Ghosal

Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

统计方法学 · 统计学 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

The United States Bureau of Labor Statistics collects data using survey instruments under informative sampling designs that assign probabilities of inclusion to be correlated with the response. The bureau extensively uses Bayesian…

统计方法学 · 统计学 2017-10-26 Terrance D. Savitsky , Sanvesh Srivastava

In this paper, we develop a semiparametric sensitivity analysis approach designed to address unmeasured confounding in observational studies with time-to-event outcomes. We target estimation of the marginal distributions of potential…

统计方法学 · 统计学 2025-11-21 Linda Amoafo , Shiyao Xu , Elizabeth Platz , Daniel Scharfstein

We cover how to determine a sufficiently large sample size for a $K$-armed randomized experiment in order to estimate conditional counterfactual expectations in data-driven subgroups. The sub-groups can be output by any feature space…

机器学习 · 计算机科学 2024-03-08 Gabriel Ruiz

We investigate the utility of pretraining by contrastive self supervised learning on both natural-scene and medical imaging datasets when the unlabeled dataset size is small, or when the diversity within the unlabeled set does not lead to…

图像与视频处理 · 电气工程与系统科学 2021-09-07 Ozan Ciga , Tony Xu , Anne L. Martel

Randomized Controlled Trials (RCTs) may suffer from limited scope. In particular, samples may be unrepresentative: some RCTs over- or under- sample individuals with certain characteristics compared to the target population, for which one…

统计方法学 · 统计学 2024-03-15 Bénédicte Colnet , Julie Josse , Gaël Varoquaux , Erwan Scornet
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