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The structure of molecular networks derives from dynamical processes on evolutionary time scales. For protein interaction networks, global statistical features of their structure can now be inferred consistently from several…

统计力学 · 物理学 2007-05-23 Johannes Berg , Michael Lässig , Andreas Wagner

Shaped by natural selection and other evolutionary forces, an organism's evolutionary history is reflected through its genome sequence, content of functional elements and organization. Consequently, organisms connected through phylogeny,…

基因组学 · 定量生物学 2023-06-16 Serena Lam , Giorgio Gonnella

Evolution is often understood through genetic mutations driving changes in an organism's fitness, but there is potential to extend this understanding beyond the genetic code. We propose that natural products - complex molecules central to…

种群与进化 · 定量生物学 2024-09-11 Sebastian Pagel , Abhishek Sharma , Leroy Cronin

In the principles-and-parameters framework, the structural features of languages depend on parameters that may be toggled on or off, with a single parameter often dictating the status of multiple features. The implied covariance between…

计算与语言 · 计算机科学 2019-05-16 Johannes Bjerva , Yova Kementchedjhieva , Ryan Cotterell , Isabelle Augenstein

Since the time of Darwin, scientists have struggled to reconcile the evolution of biological forms in a universe determined by fixed laws. These laws underpin the origin of life, evolution, human culture and technology, as set by the…

The classification of life should be based upon the fundamental mechanism in the evolution of life. We found that the global relationships among species should be circular phylogeny, which is quite different from the common sense based upon…

基因组学 · 定量生物学 2009-12-16 Dirson Jian Li , Shengli Zhang

Just as physicists strive to develop a TOE (theory of everything), which explains and unifies the physical laws of the universe, the life-scientist wishes to uncover the TOE as it relates to cellular systems. This can only be achieved with…

When we speak, write or listen, we continuously make predictions based on our knowledge of a language's grammar. Remarkably, children acquire this grammatical knowledge within just a few years, enabling them to understand and generalise to…

计算与语言 · 计算机科学 2024-11-26 Jaap Jumelet

All living organisms use the same genetic languages in their molecular biology machinery. They can be understood as the optimal solutions to the replication tasks involving DNA and proteins. These solutions perfectly fit the pattern…

其他定量生物学 · 定量生物学 2025-05-21 Apoorva D. Patel

The present view of biological phenomena is based on a biochemical paradigm that development of living organisms is defined by information stored in a molecular form as some genetic code. However, new discoveries indicate that biological…

其他定量生物学 · 定量生物学 2023-11-14 Yuri K. Shestopaloff

There is an intrinsic relationship between the molecular evolution in primordial period and the properties of genomes and proteomes of contemporary species. The genomic data may help us understand the driving force of evolution of life at…

基因组学 · 定量生物学 2009-11-25 Dirson Jian Li , Shengli Zhang

Languages and genes are both transmitted from generation to generation, with opportunity for differential reproduction and survivorship of forms. Here we apply a rigorous inference framework, drawn from population genetics, to distinguish…

种群与进化 · 定量生物学 2017-11-07 Christopher A. Ahern , Mitchell G. Newberry , Robin Clark , Joshua B. Plotkin

Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics…

其他定量生物学 · 定量生物学 2018-02-26 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have…

统计力学 · 物理学 2007-05-23 Ricard V. Sole , Romualdo Pastor-Satorras , Eric Smith , Thomas B. Kepler

Many of life's most fascinating phenomena emerge from interactions among many elements--many amino acids determine the structure of a single protein, many genes determine the fate of a cell, many neurons are involved in shaping our thoughts…

定量方法 · 定量生物学 2011-11-28 Thierry Mora , William Bialek

The evolution in coding DNA sequences brings new flexibility and freedom to the codon words, even as the underlying nucleotides get significantly ordered. These curious contra-rules of gene organisation are observed from the distribution of…

生物物理 · 物理学 2007-05-23 Sujay Chattopadhyay , William A. Kanner , Jayprokas Chakrabarti

A new account of parameter setting during grammatical acquisition is presented in terms of Generalized Categorial Grammar embedded in a default inheritance hierarchy, providing a natural partial ordering on the setting of parameters.…

cmp-lg · 计算机科学 2008-02-03 Ted Briscoe

This paper attempts to connects the evolution of computer languages with the evolution of life, where the later has been dictated by \emph{theory of evolution of species}, and tries to give supportive evidence that the new languages are…

编程语言 · 计算机科学 2020-07-07 K. R. Chowdhary

Languages vary considerably in syntactic structure. About 40% of the world's languages have subject-verb-object order, and about 40% have subject-object-verb order. Extensive work has sought to explain this word order variation across…

计算与语言 · 计算机科学 2022-06-10 Michael Hahn , Yang Xu

Understanding how cognitive and social mechanisms shape the evolution of complex artifacts such as songs is central to cultural evolution research. Social network topology (what artifacts are available?), selection (which are chosen?), and…

社会与信息网络 · 计算机科学 2025-02-19 Raja Marjieh , Manuel Anglada-Tort , Thomas L. Griffiths , Nori Jacoby