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Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

种群与进化 · 定量生物学 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

As early indicated by Charles Darwin, languages behave and change very much like living species. They display high diversity, differentiate in space and time, emerge and disappear. A large body of literature has explored the role of…

种群与进化 · 定量生物学 2010-04-27 Ricard V. Solé , Bernat Corominas-Murtra , Jordi Fortuny

Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables. These universals include the log-normal distribution of the…

种群与进化 · 定量生物学 2015-05-30 Eugene V. Koonin

Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code…

基因组学 · 定量生物学 2007-05-23 Dirson Jian Li

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

机器学习 · 计算机科学 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

The holographic bound in physics constrains the complexity of life. The finite storage capability of information in the observable universe requires the protein linguistics in the evolution of life. We find that the evolution of genetic…

基因组学 · 定量生物学 2007-05-23 Dirson Jian Li , Shengli Zhang

Traditional linguistic theories have largely regard language as a formal system composed of rigid rules. However, their failures in processing real language, the recent successes in statistical natural language processing, and the findings…

计算与语言 · 计算机科学 2020-12-02 Shuiyuan Yu , Chunshan Xu , Haitao Liu

We propose a model for the evolutionary ecology of words as one attempt to extend evolutionary game theory and agent-based models by utilizing the rich linguistic expressions of Large Language Models (LLMs). Our model enables the emergence…

种群与进化 · 定量生物学 2025-05-12 Reiji Suzuki , Takaya Arita

The inheritance of characteristics induced by the environment has often been opposed to the theory of evolution by natural selection. Yet, while evolution by natural selection requires new heritable traits to be produced and transmitted, it…

种群与进化 · 定量生物学 2015-06-18 Olivier Rivoire , Stanislas Leibler

Current-day genomes bear the mark of the evolutionary processes. One of the strongest indications is the sequence homology among families of proteins that perform similar biological functions in different species. The number of proteins in…

生物物理 · 物理学 2007-05-23 Joel S. Bader

Programming languages are engineered languages that allow to instruct a machine and share algorithmic information; they have a great influence on the society since they underlie almost every information technology artefact, and they are at…

编程语言 · 计算机科学 2015-10-16 Silvia Crafa

Protein evolution underpins life, and understanding its behavior as a system is of great importance. However, our current models of protein evolution are arguably too simplistic to allow quantitative interpretation and prediction of…

The theory of evolution by natural selection cannot be used to evaluate the truth value of the following proposition: Through evolution, there exists at least one species that can adapt to any one given environment. To address this issue,…

生物物理 · 物理学 2022-08-17 Kai Xu

Over the past decade, machine learning has revolutionized computers' ability to analyze text through flexible computational models. Due to their structural similarity to written language, transformer-based architectures have also shown…

Biological evolution is realised through the same mechanisms of birth and death that underlie change in population density. The deep interdependence between ecology and evolution is well-established, and recent models focus on integrating…

种群与进化 · 定量生物学 2025-10-14 A. Bradley Duthie , Victor J. Luque

We apply the theory of learning to physically renormalizable systems in an attempt to develop a theory of biological evolution, including the origin of life, as multilevel learning. We formulate seven fundamental principles of evolution…

种群与进化 · 定量生物学 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

Constraints on changes in expression levels across all cell components imposed by the steady growth of cells have recently been discussed both experimentally and theoretically. By assuming a small environmental perturbation and considering…

种群与进化 · 定量生物学 2018-04-18 Chikara Furusawa , Kunihiko Kaneko

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

神经与进化计算 · 计算机科学 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

Linguistic laws, the common statistical patterns of human language, have been investigated by quantitative linguists for nearly a century. Recently, biologists from a range of disciplines have started to explore the prevalence of these laws…

计算与语言 · 计算机科学 2023-10-12 Stuart Semple , Ramon Ferrer-i-Cancho , Morgan L. Gustison

Human language has a distinct systematic structure, where utterances break into individually meaningful words which are combined to form phrases. We show that natural-language-like systematicity arises in codes that are constrained by a…

计算与语言 · 计算机科学 2025-11-19 Richard Futrell , Michael Hahn
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