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It is well known that the integration among different data-sources is reliable because of its potential of unveiling new functionalities of the genomic expressions which might be dormant in a single source analysis. Moreover, different…

统计方法学 · 统计学 2021-12-08 Arnab Kumar Maity , Sang Chan Lee , Bani K. Mallick , Tapasree Roy Sarkar

Many complex diseases are known to be affected by the interactions between genetic variants and environmental exposures beyond the main genetic and environmental effects. Study of gene-environment (G$\times$E) interactions is important for…

统计方法学 · 统计学 2019-10-01 Jie Ren , Fei Zhou , Xiaoxi Li , Qi Chen , Hongmei Zhang , Shuangge Ma , Yu Jiang , Cen Wu

A representation of the cause-effect mechanism is needed to enable artificial intelligence to represent how the world works. Bayesian Networks (BNs) have proven to be an effective and versatile tool for this task. BNs require constructing a…

人工智能 · 计算机科学 2026-03-18 Joverlyn Gaudillo , Nicole Astrologo , Fabio Stella , Enzo Acerbi , Francesco Canonaco

The explosion in high-resolution data capture technologies in health has increased interest in making inferences about individual-level parameters. While technology may provide substantial data on a single individual, how best to use…

统计方法学 · 统计学 2021-12-16 Ziyu Ji , Julian Wolfson

Without loss of generality, existing machine learning techniques may learn spurious correlation dependent on the domain, which exacerbates the generalization of models in out-of-distribution (OOD) scenarios. To address this issue, recent…

机器学习 · 计算机科学 2024-06-18 Bin Qin , Jiangmeng Li , Yi Li , Xuesong Wu , Yupeng Wang , Wenwen Qiang , Jianwen Cao

Linear mixed effects models are widely used in statistical modelling. We consider a mixed effects model with Bayesian variable selection in the random effects using spike-and-slab priors and developed a variational Bayes inference scheme…

统计方法学 · 统计学 2024-08-15 M-Z. Spyropoulou , J. Hopker , J. E. Griffin

Robust decision making involves making decisions in the presence of uncertainty and is often used in critical domains such as healthcare, supply chains, and finance. Causality plays a crucial role in decision-making as it predicts the…

统计方法学 · 统计学 2025-07-23 Saideep Nannapaneni , Joseph Sakaya , Kyle Caron , Pedro HM Albuquerque , Zaid Tashman

Machine learning is a rapidly evolving field with a wide range of applications, including biological signal analysis, where novel algorithms often improve the state-of-the-art. However, robustness to algorithmic variability - measured by…

信号处理 · 电气工程与系统科学 2024-02-16 Tobias Ettling , Sari Saba-Sadiya , Gemma Roig

We propose the spatial-temporal aggregated predictor (STAP) modeling framework to address measurement and estimation issues that arise when assessing the relationship between built environment features (BEF) and health outcomes. Many BEFs…

统计方法学 · 统计学 2021-05-25 Adam Peterson , Jana Hirsch , Brisa Sanchez

Understanding model's sensitivity to its training data is crucial but can also be challenging and costly, especially during training. To simplify such issues, we present the Memory-Perturbation Equation (MPE) which relates model's…

机器学习 · 计算机科学 2024-01-17 Peter Nickl , Lu Xu , Dharmesh Tailor , Thomas Möllenhoff , Mohammad Emtiyaz Khan

Multivariate data that combine binary, categorical, count and continuous outcomes are common in the social and health sciences. We propose a semiparametric Bayesian latent variable model for multivariate data of arbitrary type that does not…

应用统计 · 统计学 2014-01-14 Jonathan Gruhl , Elena A. Erosheva , Paul K. Crane

The cyclical and heterogeneous nature of many substance use disorders highlights the need to adapt the type or the dose of treatment to accommodate the specific and changing needs of individuals. The Adaptive Treatment for Alcohol and…

统计方法学 · 统计学 2020-05-22 William J. Artman , Ashkan Ertefaie , Kevin G. Lynch , James R. McKay , Brent A. Johnson

Quantile regression is a powerful tool for inferring how covariates affect specific percentiles of the response distribution. Existing methods either estimate conditional quantiles separately for each quantile of interest or estimate the…

统计方法学 · 统计学 2024-11-19 Joseph Feldman , Daniel Kowal

Computer Vision practitioners must thoroughly understand their model's performance, but conditional evaluation is complex and error-prone. In biometric verification, model performance over continuous covariates---real-number attributes of…

机器学习 · 计算机科学 2020-09-22 Mel McCurrie , Hamish Nicholson , Walter J. Scheirer , Samuel Anthony

Estimating health indicators for restricted sub-populations is a recurring challenge in epidemiology and public health. When survey data are used, Small Area Estimation (SAE) methods can improve precision by borrowing strength across…

统计方法学 · 统计学 2026-01-28 Aldo Gardini , Lorenzo Mori

We propose an interdisciplinary framework that combines Bayesian predictive inference, a well-established tool in Machine Learning, with Formal Methods rooted in the computer science community. Bayesian predictive inference allows for…

统计计算 · 统计学 2025-08-21 Laura Vana , Ennio Visconti , Laura Nenzi , Annalisa Cadonna , Gregor Kastner

Analyzing multivariate count data generated by high-throughput sequencing technology in microbiome research studies is challenging due to the high-dimensional and compositional structure of the data and overdispersion. In practice,…

应用统计 · 统计学 2023-11-03 Jingyan Fu , Matthew D. Koslovsky , Andreas M. Neophytou , Marina Vannucci

Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint models are still rare and the traditional proportional hazards formulation of the time-to-event part of the model is…

统计方法学 · 统计学 2024-06-25 Anja Rappl , Thomas Kneib , Stefan Lang , Elisabeth Bergherr

Mean plausible values can be computed when Bayesian structural equation modeling (BSEM) is performed. As mean plausible values do not preserve the inter-factor correlations, they yield path coefficients that are different from the estimated…

应用统计 · 统计学 2022-08-25 André Beauducel , Norbert Hilger

Standard causal inference characterizes treatment effect through averages, but the counterfactual distributions could be different in not only the central tendency but also spread and shape. To provide a comprehensive evaluation of…

统计方法学 · 统计学 2022-11-04 Steven G. Xu , Shu Yang , Brian J. Reich