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相关论文: Towards Incorporating Entity-specific Knowledge Gr…

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In recent years, we have witnessed the proliferation of knowledge graphs (KG) in various domains, aiming to support applications like question answering, recommendations, etc. A frequent task when integrating knowledge from different KGs is…

数据库 · 计算机科学 2023-06-08 Nikolaos Fanourakis , Vasilis Efthymiou , Dimitris Kotzinos , Vassilis Christophides

Knowledge Graphs, such as Wikidata, comprise structural and textual knowledge in order to represent knowledge. For each of the two modalities dedicated approaches for graph embedding and language models learn patterns that allow for…

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Knowledge graphs (KGs) are powerful tools that codify relational behaviour between entities in knowledge bases. KGs can simultaneously model many different types of subject-predicate-object and higher-order relations. As such, they offer a…

社会与信息网络 · 计算机科学 2020-10-27 Charilaos I. Kanatsoulis , Nicholas D. Sidiropoulos

Drug repositioning-a promising strategy for discovering new therapeutic uses for existing drugs-has been increasingly explored in the computational science literature using biomedical databases. However, the technological potential of drug…

人工智能 · 计算机科学 2024-07-25 Yongseung Jegal , Jaewoong Choi , Jiho Lee , Ki-Su Park , Seyoung Lee , Janghyeok Yoon

We propose an end-to-end model to predict drug-drug interactions (DDIs) by employing graph-augmented convolutional networks. And this is implemented by combining graph CNN with an attentive pooling network to extract structural relations…

机器学习 · 计算机科学 2025-07-01 Yi Zhong , Xueyu Chen , Yu Zhao , Xiaoming Chen , Tingfang Gao , Zuquan Weng

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

人工智能 · 计算机科学 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…

人工智能 · 计算机科学 2019-03-08 Junyuan Shang , Cao Xiao , Tengfei Ma , Hongyan Li , Jimeng Sun

Learning low-dimensional embeddings of knowledge graphs is a powerful approach used to predict unobserved or missing edges between entities. However, an open challenge in this area is developing techniques that can go beyond simple edge…

社会与信息网络 · 计算机科学 2019-10-30 William L. Hamilton , Payal Bajaj , Marinka Zitnik , Dan Jurafsky , Jure Leskovec

The rapid growth in literature accumulates diverse and yet comprehensive biomedical knowledge hidden to be mined such as drug interactions. However, it is difficult to extract the heterogeneous knowledge to retrieve or even discover the…

计算与语言 · 计算机科学 2021-01-26 Lei Huang , Jiecong Lin , Xiangtao Li , Linqi Song , Ka-Chun Wong

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

机器学习 · 计算机科学 2024-04-24 Rita T. Sousa , Heiko Paulheim

Coreference resolution across multiple documents poses a significant challenge in natural language processing, particularly within the domain of knowledge graphs. This study introduces an innovative method aimed at identifying and resolving…

计算与语言 · 计算机科学 2025-04-09 Zhang Dong , Mingbang Wang , Songhang deng , Le Dai , Jiyuan Li , Xingzu Liu , Ruilin Nong

Drug-target interaction (DTI) prediction plays a crucial role in drug discovery, and deep learning approaches have achieved state-of-the-art performance in this field. We introduce an ensemble of deep learning models (EnsembleDLM) for DTI…

生物大分子 · 定量生物学 2022-01-19 Po-Yu Kao , Shu-Min Kao , Nan-Lan Huang , Yen-Chu Lin

Drug repositioning (DR) refers to identification of novel indications for the approved drugs. The requirement of huge investment of time as well as money and risk of failure in clinical trials have led to surge in interest in drug…

计算与语言 · 计算机科学 2017-05-23 Sahil Manchanda , Ashish Anand

Injecting textual information into knowledge graph (KG) entity representations has been a worthwhile expedition in terms of improving performance in KG oriented tasks within the NLP community. External knowledge often adopted to enhance KG…

计算与语言 · 计算机科学 2023-10-26 Micheal Abaho , Yousef H. Alfaifi

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

计算与语言 · 计算机科学 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Structured and unstructured data and facts about drugs, genes, protein, viruses, and their mechanism are spread across a huge number of scientific articles. These articles are a large-scale knowledge source and can have a huge impact on…

人工智能 · 计算机科学 2023-02-24 Md. Rezaul Karim , Lina Molinas Comet , Oya Beyan , Dietrich Rebholz-Schuhmann , Stefan Decker

In Track-1 of the BioCreative VII Challenge participants are asked to identify interactions between drugs/chemicals and proteins. In-context named entity annotations for each drug/chemical and protein are provided and one of fourteen…

计算与语言 · 计算机科学 2021-12-01 Virginia Adams , Hoo-Chang Shin , Carol Anderson , Bo Liu , Anas Abidin

Joint entity-relation extraction is a critical task in transforming unstructured or semi-structured text into triplets, facilitating the construction of large-scale knowledge graphs, and supporting various downstream applications. Despite…

计算与语言 · 计算机科学 2025-02-14 Danni Feng , Runzhi Li , Jing Wang , Siyu Yan , Lihong Ma , Yunli Xing

Contextual word embedding models, such as BioBERT and Bio_ClinicalBERT, have achieved state-of-the-art results in biomedical natural language processing tasks by focusing their pre-training process on domain-specific corpora. However, such…

计算与语言 · 计算机科学 2021-06-04 George Michalopoulos , Yuanxin Wang , Hussam Kaka , Helen Chen , Alexander Wong