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Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy, which, in turn, is the leading cause of end-stage chronic kidney disease. The early identification of individuals at heightened risk of such…

定量方法 · 定量生物学 2024-09-24 Davide Dei Cas , Barbara Di Camillo , Gian Paolo Fadini , Giovanni Sparacino , Enrico Longato

In recurrent survival analysis where the event of interest can occur multiple times for each subject, frailty models play a crucial role by capturing unobserved heterogeneity at the subject level within a population. Frailty models…

统计方法学 · 统计学 2024-10-30 Borna Bateni , Peyman Bateni , Bishwadeep Bhattacharyya , Devin Reeh

Understanding disease progression at the molecular pathway level usually requires capturing both structural dependencies between pathways and the temporal dynamics of disease evolution. In this work, we solve the former challenge by…

机器学习 · 计算机科学 2025-02-11 Dai Shi , Kuan Yan , Lequan Lin , Yue Zeng , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

Preventable or undiagnosed visual impairment and blindness affect billion of people worldwide. Automated multi-disease detection models offer great potential to address this problem via clinical decision support in diagnosis. In this work,…

图像与视频处理 · 电气工程与系统科学 2021-03-30 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

Diabetic Retinopathy (DR) has emerged as a major cause of preventable blindness in recent times. With timely screening and intervention, the condition can be prevented from causing irreversible damage. The work introduces a state-of-the-art…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Saksham Kumar , D Sridhar Aditya , T Likhil Kumar , Thulasi Bikku , Srinivasarao Thota , Chandan Kumar

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

机器学习 · 计算机科学 2024-06-12 Ashwin Ram

Skin cancer, a deadly form of cancer, exhibits a 23\% survival rate in the USA with late diagnosis. Early detection can significantly increase the survival rate, and facilitate timely treatment. Accurate biomedical image classification is…

计算机视觉与模式识别 · 计算机科学 2023-07-04 Abel Reyes-Angulo , Sidike Paheding

Pathology context and expert experience play significant roles in clinical ocular disease diagnosis. Although deep neural networks (DNNs) have good ocular disease recognition results, they often ignore exploring the clinical pathology…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Zunjie Xiao , Xiaoqing Zhang , Risa Higashita , Jiang Liu

Diabetic Retinopathy (DR) is a significant cause of blindness globally, highlighting the urgent need for early detection and effective treatment. Recent advancements in Machine Learning (ML) techniques have shown promise in DR detection,…

计算机视觉与模式识别 · 计算机科学 2023-09-06 D. Dhinakaran , L. Srinivasan , D. Selvaraj , S. M. Udhaya Sankar

Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

图像与视频处理 · 电气工程与系统科学 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

Trajectory prediction is critical for autonomous driving, enabling safe and efficient planning in dense, dynamic traffic. Most existing methods optimize prediction accuracy under fixed-length observations. However, real-world driving often…

机器人学 · 计算机科学 2026-03-12 Hao Zhou , Lu Qi , Jason Li , Jie Zhang , Yi Liu , Xu Yang , Mingyu Fan , Fei Luo

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…

图像与视频处理 · 电气工程与系统科学 2025-09-03 Idowu Paul Okuwobi , Jingyuan Liu , Jifeng Wan , Jiaojiao Jiang

Disease modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal observations and provide no uncertainty quantification, rendering them impractical at the critical first…

机器学习 · 计算机科学 2026-04-13 Alireza Moayedikia , Sara Fin , Uffe Kock Wiil

This paper introduces a new unsupervised method for dimensionality reduction via regression (DRR). The algorithm belongs to the family of invertible transforms that generalize Principal Component Analysis (PCA) by using curvilinear instead…

机器学习 · 统计学 2016-02-02 Valero Laparra , Jesus Malo , Gustau Camps-Valls

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

Diabetic retinopathy (DR) is one of the leading causes of blindness. However, no specific symptoms of early DR lead to a delayed diagnosis, which results in disease progression in patients. To determine the disease severity levels,…

计算机视觉与模式识别 · 计算机科学 2020-11-05 Li Tian , Liyan Ma , Zhijie Wen , Shaorong Xie , Yupeng Xu

Diabetic retinopathy (DR) is a significant cause of vision impairment, emphasizing the critical need for early detection and timely intervention to avert visual deterioration. Diagnosing DR is inherently complex, as it necessitates the…

图像与视频处理 · 电气工程与系统科学 2024-01-26 Mohamed R. Shoaib , Heba M. Emara , Jun Zhao , Walid El-Shafai , Naglaa F. Soliman , Ahmed S. Mubarak , Osama A. Omer , Fathi E. Abd El-Samie , Hamada Esmaiel

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

计算机视觉与模式识别 · 计算机科学 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

Parkinson's disease (PD) is one of the major public health problems in the world. It is a well-known fact that around one million people suffer from Parkinson's disease in the United States whereas the number of people suffering from…

机器学习 · 计算机科学 2016-10-27 Kamal Nayan Reddy Challa , Venkata Sasank Pagolu , Ganapati Panda , Babita Majhi

Clinical outcome or severity prediction from medical images has largely focused on learning representations from single-timepoint or snapshot scans. It has been shown that disease progression can be better characterized by temporal imaging.…

图像与视频处理 · 电气工程与系统科学 2022-04-01 Aishik Konwer , Xuan Xu , Joseph Bae , Chao Chen , Prateek Prasanna