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Outer hair cell (OHC) nonlinear capacitance (NLC) represents voltage sensor charge movements of prestin (SLC26a5), the protein responsible for OHC electromotility. Previous measures of NLC frequency response have employed methods which did…

生物物理 · 物理学 2020-04-15 Joseph Santos-Sacchi , Winston Tan

The outer hair cell (OHC) of the organ of Corti underlies a mechanically based process that enhances hearing, termed cochlear amplification. The cell possesses a unique motor protein, prestin, which senses voltage and consequently changes…

生物物理 · 物理学 2020-01-29 Joseph Santos-Sacchi , Kuni Iwasa , Winston Tan

Prestin (SLC26A5), a protein essential for the sensitivity of the mammalian ear, was so named from \emph{presto}. The assumption was that this membrane protein supports fast movement of outer hair cells (OHCs) that matches the mammalian…

生物物理 · 物理学 2024-03-27 Kuni H. Iwasa

Outer hair cells in the inner ear is important for the sensitivity, frequency selectivity, and dynamic range of the mammalian ear. Such a physiological role of outer hair cells is thought to be based an amplifying effect of those cells,…

生物物理 · 物理学 2020-02-04 Kuni H Iwasa

The ability of the mammalian ear in processing high frequency sounds, up to $\sim$100 kHz, is based on the capability of outer hair cells (OHCs) responding to stimulation at high frequencies. These cells show a unique motility in their cell…

生物物理 · 物理学 2017-09-22 Kuni H Iwasa

Cochlear outer hair cells (OHCs) have two mechanosensitive elements: the hair bundle with mechanotrasducer channels and the piezoelectric lateral wall of the cell body. The present report examines how these elements interact with each other…

生物物理 · 物理学 2025-09-09 Kuni H Iwasa

Electromotility of outer hair cells (OHCs) has been extensively studied with in vitro experiments because of its physiological significance in the cochlear amplifier, which provides the exquisite sensitivity and frequency selectivity of the…

生物物理 · 物理学 2016-12-08 Kuni H Iwasa

The effectiveness of outer hair cells (OHCs) in amplifying the motion of the organ of Corti, and thereby contributing to the sensitivity of mammalian hearing, depends on the mechanical power output of these cells. Electromechanical coupling…

生物物理 · 物理学 2021-01-06 Kuni H. Iwasa

High energy proton-proton and antiproton-proton elastic scattering are studied first in a model where the nucleon has an outer cloud and an inner core. Elastic scattering is viewed as due to two processes: a) diffraction scattering…

高能物理 - 唯象学 · 物理学 2011-01-27 M. M. Islam , R. J. Luddy , A. V. Prokudin

The behavior of a non-conductive quasi-planar lipid membrane in an electrolyte and in a static (DC) electric field is investigated theoretically in the nonlinear (Poisson-Boltzmann) regime. Electrostatic effects due to charges in the…

软凝聚态物质 · 物理学 2015-05-18 Falko Ziebert , David Lacoste

Stiff, elongated biomolecules such as filamentous viruses, DNA or cellulose nanocrystals are known to form liquid crystals often exhibiting a helical supramolecular organization. Little is known about the microscopic origin, size and…

软凝聚态物质 · 物理学 2016-08-06 Štěpán Růžička , Henricus H. Wensink

We predict pp elastic differential cross section at LHC at the c.m. energy 14 TeV and momentum transfer range |t| = 0-10 GeV*2, which is planned to be measured by the TOTEM group. The field theory model underlying our phenomenological…

高能物理 - 唯象学 · 物理学 2007-05-23 M. M. Islam , R. J. Luddy , A. V. Prokudin

Intracellular recordings of cortical neurons in vivo display intense subthreshold membrane potential (Vm) activity. The power spectral density (PSD) of the Vm displays a power-law structure at high frequencies (>50 Hz) with a slope of about…

神经元与认知 · 定量生物学 2009-11-13 Claude Bedard , Alain Destexhe

We predict pp elastic differential cross sections at LHC at c.m. energy 14 TeV and momentum transfer range |t| = 0 - 10 GeV*2 in a nucleon-structure model. In this model, the nucleon has an outer cloud of quark-antiquark condensed ground…

高能物理 - 唯象学 · 物理学 2007-08-10 M. M. Islam , J. Kaspar , R. J. Luddy

X-ray diffraction pattern and Raman spectrum authenticate the monoclinic P21/n structure of polycrystalline Pr$_2$ZnMnO$_6$ (PZM) synthesized by the solid-state reaction technique. The X-ray photoemission spectrum suggests the existence of…

材料科学 · 物理学 2023-07-04 Moumin Rudra , H. S. Tripathi , Alo Dutta , T. P. Sinha

We study the static and dynamic structure of thermally fluctuating elastic thin sheets by investigating the overdamped dynamic F\"oppl-von K\'arm\'an equation, in which the F\"oppl-von K\'arm\'an equation from elasticity theory is driven by…

软凝聚态物质 · 物理学 2023-05-10 Chanania Steinbock , Eytan Katzav

A description of phonon dynamics and charge response of the $n$-doped high-temperature superconductor (HTSC) NdCuO is presented based upon a microscopic modeling of the electronic density response. This is accomplished starting from the…

超导电性 · 物理学 2009-11-13 Thomas Bauer , Claus Falter

Avian prestin is sensitive to membrane thickness as much as mammalian prestin, which undergoes conformational transitions in membrane area and thereby drives length changes of the cylindrical cell body of outer hair cells. The membrane…

生物物理 · 物理学 2023-07-06 Kuni H Iwasa

Biomembranes are thin capacitors with the unique feature of displaying phase transitions in a physiologically relevant regime. We investigate the voltage and lateral pressure dependence of their capacitance close to their chain melting…

生物物理 · 物理学 2012-09-18 Thomas Heimburg

Transients of a grid-synchronized voltage source converter (VSC) are closely related to over- currents and voltages occurred under large disturbances (e.g. a grid fault). Previous analysis in evaluating these transients usually neglect the…

系统与控制 · 计算机科学 2018-07-02 Chen Zhang , Marta Molinas , Xu Cai , Atle Rygg
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