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Precision medicine is a paradigm shift in healthcare relying heavily on genomics data. However, the complexity of biological interactions, the large number of genes as well as the lack of comparisons on the analysis of data, remain a…

Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…

Nanoscale phase-control is one of the most powerful approaches to specifically tailor electrical fields in modern nanophotonics. Especially the precise sub-wavelength assembly of many individual nano-building-blocks has given rise to…

光学 · 物理学 2021-05-26 Lisa Saemisch , Niek F. van Hulst , Matz Liebel

Two-dimensional (2d) nano-electronics, plasmonics, and emergent phases require clean and local charge control, calling for layered, crystalline acceptors or donors. Our Raman, photovoltage, and electrical conductance measurements combined…

While we once thought of cancer as single monolithic diseases affecting a specific organ site, we now understand that there are many subtypes of cancer defined by unique patterns of gene mutations. These gene mutational data, which can be…

定量方法 · 定量生物学 2017-03-07 Jipeng Qiang , Wei Ding , John Quackenbush , Ping Chen

The hotspots, which are typically found in nanogaps between metal structures, are critical for the enhancement of the electromagnetic field. Surface-enhanced Raman scattering (SERS), a technique known for its exceptional sensitivity and…

光学 · 物理学 2025-01-22 Mahsa Haddadi Moghaddam , Sobhagyam Sharma , Daehwan Park , Dai Sik Kim

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some…

光学 · 物理学 2017-11-28 S. Hamed Shams Mousavi , Ali A. Eftekhar , Amir H. Atabaki , Ali Adibi

Deploying motile nanosized particles, also known as ``nanobots'', in the human body promises to improve selectivity in drug delivery and reduce side effects. We consider a swarm of nanobots locating a single cancerous region and treating it…

多智能体系统 · 计算机科学 2025-07-17 Noble Harasha , Cristina Gava , Nancy Lynch , Claudia Contini , Frederik Mallmann-Trenn

Lateral two-dimensional (2D) transitional metal dichalcogenide (TMD) heterostructures have recently attracted a wide attention as promising materials for optoelectronic nanodevices. Due to the nanoscale width of lateral heterojunctions, the…

光学 · 物理学 2018-07-18 Chenwei Tang , Zhe He , Weibing Chen , Shuai Jia , Jun Lou , Dmitri V. Voronine

Plasmonic metamaterials can be used to enhance mid-infrared sensors and detectors for immunosensing applications. The major challenge is to integrate these technologies in low-cost, compact, and promising platforms. In this study, as an…

A novel bio-photonics approach based on the nonlinear optical process of second harmonic generation by non-centrosymmetric nanoparticles is presented and demonstrated on malignant human cell lines. The proposed method allows to directly…

The increasing utilization of charged particle beams for therapeutic purposes requires designing novel detector systems which shall be capable of assessing radiation quality for a diversity of ion species. It is shown that the pattern of…

仪器与探测器 · 物理学 2009-09-30 M. Hajek

Plasmonic detectors have the potential to provide a method of rapid spectroscopy without the need of moving mirrors or gratings. Previous measurements have demonstrated frequency tunable detection based on plasmonic excitations, however…

材料科学 · 物理学 2015-02-09 Che Jin Bae , Deepu George , Rohit Singh , Gottfried Strasser , Andrea Markelz

Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability…

Extreme light confinement down to the atomic scale has been theoretically predicted for ultrathin, Ta-based transition metal dichalcogenides (TMDs). In this work, we experimentally demonstrate in 2H-TaS$_2$ monolayers and bilayers a lateral…

Photothermal therapy (PTT) has shown significant potential in cancer treatment. However, developing nanomaterial-based photothermal agents with good biocompatibility and high photothermal conversion efficiency (PTCE) remains a key…

Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

An exact, analytic solution for a simple electrostatic model applicable to biomolecular recognition is presented. In the model, a layer of high dielectric constant material (representative of the solvent, water) whose thickness may vary…

经典物理 · 物理学 2013-05-29 T. P. Doerr , Yi-Kuo Yu

Two-dimensional (2D) materials beyond graphene such as transition metal dichalcogenides (TMDs) have unique mechanical, optical and electronic properties with promising applications in flexible devices, catalysis and sensing. Optical imaging…

We developed planar multilayered photonic-plasmonic structures, which support topologically protected optical states on the interface between metal and dielectric materials, known as optical Tamm states. Coupling of incident light to the…